C‐type lectin receptors MR and DC‐SIGN are involved in recognition of hemocyanins, shaping their immunostimulatory effects on human dendritic cells

Intensive therapy with gastropodan hemocyanins increases their antitumor properties in murine model of colon carcinoma

(2020) Emiliya Stoyanova et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

A heat-shocked melanoma cell lysate vaccine enhances tumor infiltration by prototypic effector T cells inhibiting tumor growth

(2020) María Alejandra Gleisner et al.   Journal for ImmunoTherapy of Cancer

Hemocyanins from Helix and Rapana Snails Exhibit in Vitro Antitumor Effects in Human Colorectal Adenocarcinoma

(2020) Ani Georgieva et al.   Biomedicines

Human Dendritic Cells: Their Heterogeneity and Clinical Application Potential in Cancer Immunotherapy

(2019) Thiago A. Patente et al.   Frontiers in Immunology

Selection of adjuvants for vaccines targeting specific pathogens

(2019) Indranil Sarkar et al.   Expert Review of Vaccines

TLR4, but Neither Dectin-1 nor Dectin-2, Participates in the Mollusk Hemocyanin-Induced Proinflammatory Effects in Antigen-Presenting Cells From Mammals

(2019) José M. Jiménez et al.   Frontiers in Immunology

Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition)

(2019) Andrea Cossarizza et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

N-Glycosylation of mollusk hemocyanins contributes to their structural stability and immunomodulatory properties in mammals

(2019) Michelle L. Salazar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of the Cell Biology of Antigen Cross-Presentation

(2018) J. Magarian Blander   Annual Review of Immunology

From Ocean to Bedside: the Therapeutic Potential of Molluscan Hemocyanins

(2018) Negar Talaei Zanjani et al.   CURRENT MEDICINAL CHEMISTRY

Antitumor activity and carrier properties of novel hemocyanins coupled to a mimotope of GD2 ganglioside

(2018) Miriam Palacios et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Flexible Signaling of Myeloid C-Type Lectin Receptors in Immunity and Inflammation

(2018) Carlos del Fresno et al.   Frontiers in Immunology

Mouse DC-SIGN/CD209a as Target for Antigen Delivery and Adaptive Immunity

(2018) Sjoerd T. T. Schetters et al.   Frontiers in Immunology

Toll-Like Receptor 4 Triggering Promotes Cytosolic Routing of DC-SIGN-Targeted Antigens for Presentation on MHC Class I

(2018) Sophie K. Horrevorts et al.   Frontiers in Immunology

Multiplex bead-based measurement of humoral immune responses against tumor-associated antigens in stage II melanoma patients of the EORTC18961 trial

(2018) Judith Michels et al.   OncoImmunology

Early events during human coronavirus OC43 entry to the cell

(2018) Katarzyna Owczarek et al.   Scientific Reports

M. tuberculosis -Initiated Human Mannose Receptor Signaling Regulates Macrophage Recognition and Vesicle Trafficking by FcRγ-Chain, Grb2, and SHP-1

(2017) Murugesan V.S. Rajaram et al.   Cell Reports

Molluskan Hemocyanins Activate the Classical Pathway of the Human Complement System through Natural Antibodies

(2017) Javier Pizarro-Bauerle et al.   Frontiers in Immunology

Heterogeneity, functional specialization and differentiation of monocyte-derived dendritic cells

(2016) Kevin V Chow et al.   IMMUNOLOGY AND CELL BIOLOGY

Hemocyanins Stimulate Innate Immunity by Inducing Different Temporal Patterns of Proinflammatory Cytokine Expression in Macrophages

(2016) Ta-Ying Zhong et al.   JOURNAL OF IMMUNOLOGY

Vaccines for feline contraception

(2015) Valerie A W Benka et al.   JOURNAL OF FELINE MEDICINE AND SURGERY

Crystal Structure of the 3.8-MDa Respiratory Supermolecule Hemocyanin at 3.0 Å Resolution

(2015) Zuoqi Gai et al.   STRUCTURE

Keyhole limpet haemocyanin - a model antigen for human immunotoxicological studies

(2014) Ashwin Swaminathan et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Diverse immune functions of hemocyanins

(2014) Christopher J. Coates et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Role of DC-SIGN in Helicobacter pylori infection of gastrointestinal cells

(2014) Jing Wu   Frontiers in Bioscience-Landmark

A Novel Immunomodulatory Hemocyanin from the Limpet Fissurella latimarginata Promotes Potent Anti-Tumor Activity in Melanoma

(2014) Sergio Arancibia et al.   PLoS One

Enhanced receptor-clathrin interactions induced by N-glycan-mediated membrane micropatterning

(2014) J. A. Torreno-Pina et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeting C-type lectin receptors with multivalent carbohydrate ligands

(2013) Bernd Lepenies et al.   ADVANCED DRUG DELIVERY REVIEWS

The Dendritic Cell Lineage: Ontogeny and Function of Dendritic Cells and Their Subsets in the Steady State and the Inflamed Setting

(2013) Miriam Merad et al.   Annual Review of Immunology

Tumour cell lysate-loaded dendritic cell vaccine induces biochemical and memory immune response in castration-resistant prostate cancer patients

(2013) D Reyes et al.   BRITISH JOURNAL OF CANCER

Signalling C-Type lectin receptors, microbial recognition and immunity

(2013) J. Claire Hoving et al.   CELLULAR MICROBIOLOGY

The physiological role of DC-SIGN: A tale of mice and men

(2013) Juan J. Garcia-Vallejo et al.   TRENDS IN IMMUNOLOGY

The mannose receptor

(2012) Luisa Martinez-Pomares   JOURNAL OF LEUKOCYTE BIOLOGY

Heat-Shock Induction of Tumor-Derived Danger Signals Mediates Rapid Monocyte Differentiation into Clinically Effective Dendritic Cells

(2011) R. Aguilera et al.   CLINICAL CANCER RESEARCH

Enhanced structural stability of Concholepas hemocyanin increases its immunogenicity and maintains its non-specific immunostimulatory effects

(2011) Sergio Arancibia et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Molecular mechanism and physiological functions of clathrin-mediated endocytosis

(2011) Harvey T. McMahon et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

High-Affinity Glycopolymer Binding to Human DC-SIGN and Disruption of DC-SIGN Interactions with HIV Envelope Glycoprotein

(2010) C. Remzi Becer et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Schistosoma mansoni worm glycolipids induce an inflammatory phenotype in human dendritic cells by cooperation of TLR4 and DC-SIGN

(2010) Caroline M.W. van Stijn et al.   MOLECULAR IMMUNOLOGY

The C-type lectin DC-SIGN internalizes soluble antigens and HIV-1 virionsviaa clathrin-dependent mechanism

(2009) Alessandra Cambi et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

C-type lectins and phagocytosis

(2009) Ann M. Kerrigan et al.   IMMUNOBIOLOGY

Influence of the mannose receptor in host immune responses

(2009) Umut Gazi et al.   IMMUNOBIOLOGY

Variable antigen uptake due to different expression of the macrophage mannose receptor by dendritic cells in various inbred mouse strains

(2009) Stella Eugenie Autenrieth et al.   IMMUNOLOGY

Prolonged Survival of Dendritic Cell–Vaccinated Melanoma Patients Correlates With Tumor-Specific Delayed Type IV Hypersensitivity Response and Reduction of Tumor Growth Factor β-Expressing T Cells

(2009) Mercedes N. López et al.   JOURNAL OF CLINICAL ONCOLOGY

Binding-site geometry and flexibility in DC-SIGN demonstrated with surface force measurements

(2009) Sindhu Menon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Endocytosis mechanisms and the cell biology of antigen presentation

(2008) Sven Burgdorf et al.   CURRENT OPINION IN IMMUNOLOGY

Dendritic cells and C-type lectin receptors: coupling innate to adaptive immune responses

(2008) Sandra J van Vliet et al.   IMMUNOLOGY AND CELL BIOLOGY

Dendritic Cell Interaction withCandida albicansCritically Depends onN-Linked Mannan

(2008) Alessandra Cambi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Keyhole Limpet Hemocyanin: 9-Å CryoEM Structure and Molecular Model of the KLH1 Didecamer Reveal the Interfaces and Intricate Topology of the 160 Functional Units

(2008) Christos Gatsogiannis et al.   JOURNAL OF MOLECULAR BIOLOGY

Keyhole limpet hemocyanin induces the activation and maturation of human dendritic cells through the involvement of mannose receptor

(2007) Pietro Presicce et al.   MOLECULAR IMMUNOLOGY