N-Glycosylation of mollusk hemocyanins contributes to their structural stability and immunomodulatory properties in mammals

Immunotherapeutic Potential of Mollusk Hemocyanins in Combination with Human Vaccine Adjuvants in Murine Models of Oral Cancer

(2019) Juan José Mora et al.   Journal of Immunology Research

Identification and characterization of glycosylation sites on Litopenaeus vannamei hemocyanin

(2019) Zehui Zhang et al.   FEBS LETTERS

Protein Glycosylation and Tumor Microenvironment Alterations Driving Cancer Hallmarks

(2019) Andreia Peixoto et al.   Frontiers in Oncology

TLR4, but Neither Dectin-1 nor Dectin-2, Participates in the Mollusk Hemocyanin-Induced Proinflammatory Effects in Antigen-Presenting Cells From Mammals

(2019) José M. Jiménez et al.   Frontiers in Immunology

Antitumor activity and carrier properties of novel hemocyanins coupled to a mimotope of GD2 ganglioside

(2018) Miriam Palacios et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Comprehensive analysis of N-glycans in IgG purified from ferrets with or without influenza A virus infection

(2018) Guozhang Zou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A standardized method for lectin microarray-based tissue glycome mapping

(2017) Xia Zou et al.   Scientific Reports

Short O-GalNAc glycans: regulation and role in tumor development and clinical perspectives

(2016) Joanne Chia et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Challenges of glycosylation analysis and control: an integrated approach to producing optimal and consistent therapeutic drugs

(2016) Peiqing Zhang et al.   DRUG DISCOVERY TODAY

Hemocyanins Stimulate Innate Immunity by Inducing Different Temporal Patterns of Proinflammatory Cytokine Expression in Macrophages

(2016) Ta-Ying Zhong et al.   JOURNAL OF IMMUNOLOGY

Hemocyanin from Shrimp Litopenaeus vannamei Has Antiproliferative Effect against HeLa Cell In Vitro

(2016) Liyuan Zheng et al.   PLoS One

Conceptual Spaces of the Immune System

(2016) Walter Fierz   Frontiers in Immunology

Crystal Structure of the 3.8-MDa Respiratory Supermolecule Hemocyanin at 3.0 Å Resolution

(2015) Zuoqi Gai et al.   STRUCTURE

Anti-cancer properties of gastropodan hemocyanins in murine model of colon carcinoma

(2014) Vera Gesheva et al.   BMC IMMUNOLOGY

Interleukin 12: still a promising candidate for tumor immunotherapy?

(2014) Witold Lasek et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

The effect of glycosylation of antigens on the antibody responses against Echinostoma caproni (Trematoda: Echinostomatidae)

(2014) JAVIER SOTILLO et al.   PARASITOLOGY

A Novel Immunomodulatory Hemocyanin from the Limpet Fissurella latimarginata Promotes Potent Anti-Tumor Activity in Melanoma

(2014) Sergio Arancibia et al.   PLoS One

In vitro Antiproliferative Effect of Helix aspersa Hemocyanin on Multiple Malignant Cell Lines

(2014) Olga Antonova et al.   ZEITSCHRIFT FUR NATURFORSCHUNG SECTION C-A JOURNAL OF BIOSCIENCES

IL-6 in Inflammation, Immunity, and Disease

(2014) T. Tanaka et al.   Cold Spring Harbor Perspectives in Biology

Fucose-specific DC-SIGN signalling directs T helper cell type-2 responses via IKKε- and CYLD-dependent Bcl3 activation

(2014) Sonja I. Gringhuis et al.   Nature Communications

Lectin-Array Blotting: Profiling Protein Glycosylation in Complex Mixtures

(2012) Juan Etxebarria et al.   ACS Chemical Biology

The sweet tooth of biopharmaceuticals: Importance of recombinant protein glycosylation analysis

(2012) Nico Lingg et al.   Biotechnology Journal

Evaluation of primary and secondary responses to a T-cell-dependent antigen, keyhole limpet hemocyanin, in rats

(2012) Ryota Kawai et al.   Journal of Immunotoxicology

Enhanced structural stability of Concholepas hemocyanin increases its immunogenicity and maintains its non-specific immunostimulatory effects

(2011) Sergio Arancibia et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Glycan structures of the structural subunit (HtH1) of Haliotis tuberculata hemocyanin

(2011) Lyudmila Velkova et al.   GLYCOCONJUGATE JOURNAL

Glycosylation of Therapeutic Proteins

(2010) Ricardo J. Solá et al.   BIODRUGS

Glycan structures and antiviral effect of the structural subunit RvH2 of Rapana hemocyanin

(2010) Pavlina Dolashka et al.   CARBOHYDRATE RESEARCH

Structure of hemocyanin from garden snail Helix lucorum

(2010) Ludmila Velkova et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY

Distribution and Function of Macrophage Galactose-type C-type Lectin 2 (MGL2/CD301b)

(2010) Kaori Denda-Nagai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Mannose Receptor Mediates the Uptake of Diverse Native Allergens by Dendritic Cells and Determines Allergen-Induced T Cell Polarization through Modulation of IDO Activity

(2010) P.-J. Royer et al.   JOURNAL OF IMMUNOLOGY

Evaluation of human antibody responses to keyhole limpet hemocyanin on a carbohydrate microarray

(2010) Oyindasola Oyelaran et al.   Proteomics Clinical Applications

C-type lectins and phagocytosis

(2009) Ann M. Kerrigan et al.   IMMUNOBIOLOGY

Immunodominant role of CCHA subunit of Concholepas hemocyanin is associated with unique biochemical properties

(2009) María Inés Becker et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Macrophages Create an Acidic Extracellular Hydrolytic Compartment to Digest Aggregated Lipoproteins

(2009) Abigail S. Haka et al.   MOLECULAR BIOLOGY OF THE CELL

Spectroscopic Properties and Conformational Stability of Concholepas concholepas Hemocyanin

(2008) Krassimira Idakieva et al.   JOURNAL OF FLUORESCENCE

Keyhole Limpet Hemocyanin: 9-Å CryoEM Structure and Molecular Model of the KLH1 Didecamer Reveal the Interfaces and Intricate Topology of the 160 Functional Units

(2008) Christos Gatsogiannis et al.   JOURNAL OF MOLECULAR BIOLOGY

Keyhole limpet hemocyanin induces the activation and maturation of human dendritic cells through the involvement of mannose receptor

(2007) Pietro Presicce et al.   MOLECULAR IMMUNOLOGY