The pathological significance of LOXL2 in pre-metastatic niche formation of HCC and its related molecular mechanism

LOXL2 Expression Status Is Correlated With Molecular Characterizations of Cervical Carcinoma and Associated With Poor Cancer Survival via Epithelial-Mesenchymal Transition (EMT) Phenotype

(2020) Canhui Cao et al.   Frontiers in Oncology

Matrix Stiffness-Upregulated MicroRNA-17-5p Attenuates the Intervention Effects of Metformin on HCC Invasion and Metastasis by Targeting the PTEN/PI3K/Akt Pathway

(2020) Xiangyu Gao et al.   Frontiers in Oncology

Immobilized Transforming Growth Factor-Beta 1 in a Stiffness-Tunable Artificial Extracellular Matrix Enhances Mechanotransduction in the Epithelial Mesenchymal Transition of Hepatocellular Carcinoma

(2019) Rui-Zhi Tang et al.   ACS Applied Materials & Interfaces

Metformin and Docosahexaenoic Acid Hybrid Micelles for Premetastatic Niche Modulation and Tumor Metastasis Suppression

(2019) Tianze Jiang et al.   NANO LETTERS

Interactions in the (Pre)metastatic Niche Support Metastasis Formation

(2019) Ginevra Doglioni et al.   Frontiers in Oncology

Higher matrix stiffness as an independent initiator triggers epithelial-mesenchymal transition and facilitates HCC metastasis

(2019) Yinying Dong et al.   Journal of Hematology & Oncology

Matrix stiffness-upregulated LOXL2 promotes fibronectin production, MMP9 and CXCL12 expression and BMDCs recruitment to assist pre-metastatic niche formation

(2018) Sifan Wu et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Colorectal cancer-derived small extracellular vesicles establish an inflammatory premetastatic niche in liver metastasis

(2018) Yingkuan Shao et al.   CARCINOGENESIS

Role of LOXL2 in the epithelial-mesenchymal transition and colorectal cancer metastasis

(2017) Pil-Gu Park et al.   Oncotarget

Characteristics and Significance of the Pre-metastatic Niche

(2016) Yang Liu et al.   CANCER CELL

Cancer Tills the Premetastatic Field: Mechanistic Basis and Clinical Implications

(2016) A. R. Chin et al.   CLINICAL CANCER RESEARCH

Matrix stiffness-mediated effects on stemness characteristics occurring in HCC cells

(2016) Yang You et al.   Oncotarget

Increased risk of hepatocellular carcinoma in chronic hepatitis B patients with transient elastography-defined subclinical cirrhosis

(2015) Mi Na Kim et al.   HEPATOLOGY

Higher Matrix Stiffness Upregulates Osteopontin Expression in Hepatocellular Carcinoma Cells Mediated by Integrin β1/GSK3β/β-Catenin Signaling Pathway

(2015) Yang You et al.   PLoS One

Increasing matrix stiffness upregulates vascular endothelial growth factor expression in hepatocellular carcinoma cells mediated by integrin β1

(2014) Yinying Dong et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Role of three-dimensional matrix stiffness in regulating the chemoresistance of hepatocellular carcinoma cells

(2014) Chang Liu et al.   BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY

Lysyl oxidase-like 2 is critical to tumor microenvironment and metastatic niche formation in hepatocellular carcinoma

(2014) Carmen Chak-Lui Wong et al.   HEPATOLOGY

The tumour-induced systemic environment as a critical regulator of cancer progression and metastasis

(2014) Sandra S. McAllister et al.   NATURE CELL BIOLOGY

Impact of liver fibrosis on prognosis following liver resection for hepatitis B-associated hepatocellular carcinoma

(2013) Q Wang et al.   BRITISH JOURNAL OF CANCER

The pre-metastatic niche: finding common ground

(2013) Jaclyn Sceneay et al.   CANCER AND METASTASIS REVIEWS

Prediction of Recurrence after Curative Resection of Hepatocellular Carcinoma using Liver Stiffness Measurement (FibroScan®)

(2012) Kyu Sik Jung et al.   ANNALS OF SURGICAL ONCOLOGY

The secreted factors responsible for pre-metastatic niche formation: Old sayings and new thoughts

(2011) Héctor Peinado et al.   SEMINARS IN CANCER BIOLOGY

The human lysyl oxidase-like 2 protein functions as an amine oxidase toward collagen and elastin

(2010) Young-Mi Kim et al.   MOLECULAR BIOLOGY REPORTS

Hypoxia-Induced Lysyl Oxidase Is a Critical Mediator of Bone Marrow Cell Recruitment to Form the Premetastatic Niche

(2009) Janine T. Erler et al.   CANCER CELL

Secreted LOXL2 is a novel therapeutic target that promotes gastric cancer metastasis via the Src/FAK pathway

(2009) Liang Peng et al.   CARCINOGENESIS