Acetaminophen metabolism revisited using non-targeted analyses: Implications for human biomonitoring

The mercapturic acid pathway

(2020) Patrick E. Hanna et al.   CRITICAL REVIEWS IN TOXICOLOGY

BioTransformer: a comprehensive computational tool for small molecule metabolism prediction and metabolite identification

(2019) Yannick Djoumbou-Feunang et al.   Journal of Cheminformatics

Urinary metabolites of the UV filter octocrylene in humans as biomarkers of exposure

(2019) Daniel Bury et al.   ARCHIVES OF TOXICOLOGY

CFM-ID 3.0: Significantly Improved ESI-MS/MS Prediction and Compound Identification

(2019) Yannick Djoumbou-Feunang et al.   Metabolites

Refined reference doses and new procedures for phthalate mixture risk assessment focused on male developmental toxicity

(2019) Andreas Kortenkamp et al.   INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH

Which chemicals should be grouped together for mixture risk assessments of male reproductive disorders?

(2019) Andreas Kortenkamp   MOLECULAR AND CELLULAR ENDOCRINOLOGY

METLIN: A Technology Platform for Identifying Knowns and Unknowns

(2018) Carlos Guijas et al.   ANALYTICAL CHEMISTRY

De-novo identification of specific exposure biomarkers of the alternative plasticizer di(2-ethylhexyl) terephthalate (DEHTP) after low oral dosage to male volunteers by HPLC-Q-Orbitrap-MS

(2018) Frederik Lessmann et al.   BIOMARKERS

Reproductive Headache? Investigating Acetaminophen as a Potential Endocrine Disruptor

(2018) Lindsey Konkel   ENVIRONMENTAL HEALTH PERSPECTIVES

Prenatal exposure to acetaminophen and children's language development at 30 months

(2018) C.-G. Bornehag et al.   EUROPEAN PSYCHIATRY

Ibuprofen alters human testicular physiology to produce a state of compensated hypogonadism

(2018) David Møbjerg Kristensen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PubChem 2019 update: improved access to chemical data

(2018) Sunghwan Kim et al.   NUCLEIC ACIDS RESEARCH

DrugBank 5.0: a major update to the DrugBank database for 2018

(2017) David S Wishart et al.   NUCLEIC ACIDS RESEARCH

HMDB 4.0: the human metabolome database for 2018

(2017) David S Wishart et al.   NUCLEIC ACIDS RESEARCH

mixOmics: An R package for ‘omics feature selection and multiple data integration

(2017) Florian Rohart et al.   PLoS Computational Biology

Disruption of the Prostaglandin Metabolome and Characterization of the Pharmaceutical Exposome in Fish Exposed to Wastewater Treatment Works Effluent As Revealed by Nanoflow-Nanospray Mass Spectrometry-Based Metabolomics

(2016) Arthur David et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Analgesic use — prevalence, biomonitoring and endocrine and reproductive effects

(2016) David M. Kristensen et al.   Nature Reviews Endocrinology

MetFrag relaunched: incorporating strategies beyond in silico fragmentation

(2016) Christoph Ruttkies et al.   Journal of Cheminformatics

Solid-Phase Extraction and Nanoflow Liquid Chromatography-Nanoelectrospray Ionization Mass Spectrometry for Improved Global Urine Metabolomics

(2015) Andrew J. Chetwynd et al.   ANALYTICAL CHEMISTRY

Human metabolism and excretion kinetics of aniline after a single oral dose

(2015) Hendrik Modick et al.   ARCHIVES OF TOXICOLOGY

N-acetyl-4-aminophenol (paracetamol) in urine samples of 6–11-year-old Danish school children and their mothers

(2015) Jeanette K.S. Nielsen et al.   INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH

PharmGKB summary

(2015) Liudmila L. Mazaleuskaya et al.   Pharmacogenetics and Genomics

Identifying Small Molecules via High Resolution Mass Spectrometry: Communicating Confidence

(2014) Emma L. Schymanski et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

A new approach for plasma (xeno)metabolomics based on solid-phase extraction and nanoflow liquid chromatography-nanoelectrospray ionisation mass spectrometry

(2014) Arthur David et al.   JOURNAL OF CHROMATOGRAPHY A

T3DB: the toxic exposome database

(2014) David Wishart et al.   NUCLEIC ACIDS RESEARCH

Ubiquitous presence of paracetamol in human urine: sources and implications

(2014) Hendrik Modick et al.   REPRODUCTION

Disruption of Thioredoxin Reductase 1 Protects Mice from Acute Acetaminophen-Induced Hepatotoxicity through Enhanced NRF2 Activity

(2013) Andrew D. Patterson et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Paracetamol, aspirin and indomethacin display endocrine disrupting properties in the adult human testis in vitro

(2013) O. Albert et al.   HUMAN REPRODUCTION

Rapid determination of N-acetyl-4-aminophenol (paracetamol) in urine by tandem mass spectrometry coupled with on-line clean-up by two dimensional turbulent flow/reversed phase liquid chromatography

(2013) Hendrik Modick et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Patient knowledge and use of acetaminophen in over-the-counter medications

(2013) Jason Hurwitz et al.   JOURNAL OF THE AMERICAN PHARMACISTS ASSOCIATION

Paracetamol (acetaminophen), aspirin (acetylsalicylic acid) and indomethacin are anti-androgenic in the rat foetal testis

(2012) D. M. Kristensen et al.   INTERNATIONAL JOURNAL OF ANDROLOGY

Cysteine S-conjugate β-lyases: important roles in the metabolism of naturally occurring sulfur and selenium-containing compounds, xenobiotics and anticancer agents

(2010) Arthur J. L. Cooper et al.   AMINO ACIDS

ChemSpider: An Online Chemical Information Resource

(2010) Harry E. Pence et al.   JOURNAL OF CHEMICAL EDUCATION

MassBank: a public repository for sharing mass spectral data for life sciences

(2010) Hisayuki Horai et al.   JOURNAL OF MASS SPECTROMETRY

Global metabolic profiling procedures for urine using UPLC–MS

(2010) Elizabeth J Want et al.   Nature Protocols