Dynamic Changes of Microglia/Macrophage M1 and M2 Polarization in Theiler's Murine Encephalomyelitis

Effector molecules released by Th1 but not Th17 cells drive an M1 response in microglia

(2014) Chittappen K. Prajeeth et al.   BRAIN BEHAVIOR AND IMMUNITY

Theiler’s virus infection provokes the overexpression of genes coding for the chemokine Ip10 (CXCL10) in SJL/J murine astrocytes, which can be inhibited by modulators of estrogen receptors

(2014) Nazario Rubio et al.   JOURNAL OF NEUROVIROLOGY

Ventral tegmental area/substantia nigra and prefrontal cortex rodent organotypic brain slices as an integrated model to study the cellular changes induced by oxygen/glucose deprivation and reperfusion: Effect of neuroprotective agents

(2014) Laura Colombo et al.   NEUROCHEMISTRY INTERNATIONAL

Transcriptomic Meta-Analysis of Multiple Sclerosis and Its Experimental Models

(2014) Barbara B. R. Raddatz et al.   PLoS One

Diverse activation of microglia by chemokine (C-C motif) ligand 2 overexpression in brain

(2013) Maj-Linda B Selenica et al.   Journal of Neuroinflammation

Macrophages in inflammatory multiple sclerosis lesions have an intermediate activation status

(2013) Daphne YS Vogel et al.   Journal of Neuroinflammation

Human Cytomegalovirus Interleukin-10 Polarizes Monocytes toward a Deactivated M2c Phenotype To Repress Host Immune Responses

(2013) S. Avdic et al.   JOURNAL OF VIROLOGY

The Role of Interleukin-6 in the Expression of PD-1 and PDL-1 on Central Nervous System Cells following Infection with Theiler's Murine Encephalomyelitis Virus

(2013) Y.-H. Jin et al.   JOURNAL OF VIROLOGY

OASL1 inhibits translation of the type I interferon–regulating transcription factor IRF7

(2013) Myeong Sup Lee et al.   NATURE IMMUNOLOGY

M2 microglia and macrophages drive oligodendrocyte differentiation during CNS remyelination

(2013) Veronique E Miron et al.   NATURE NEUROSCIENCE

Targeting the Shift from M1 to M2 Macrophages in Experimental Autoimmune Encephalomyelitis Mice Treated with Fasudil

(2013) Chunyun Liu et al.   PLoS One

Autocrine Regulation of Macrophage Activation via Exocytosis of ATP and Activation of P2Y11 Receptor

(2013) Hayato Sakaki et al.   PLoS One

Dynamic changes of Foxp3+ regulatory T cells in spleen and brain of canine distemper virus-infected dogs

(2013) V. Qeska et al.   VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY

Minocycline selectively inhibits M1 polarization of microglia

(2013) K Kobayashi et al.   Cell Death & Disease

Negative Regulation of Type I IFN Expression by OASL1 Permits Chronic Viral Infection and CD8+ T-Cell Exhaustion

(2013) Myeong Sup Lee et al.   PLoS Pathogens

Comparison of polarization properties of human adult microglia and blood-derived macrophages

(2012) Bryce A. Durafourt et al.   GLIA

Periventricular Demyelination and Axonal Pathology Is Associated with Subependymal Virus Spread in a Murine Model for Multiple Sclerosis

(2012) Maren Kummerfeld et al.   INTERVIROLOGY

Theiler's murine encephalomyelitis virus induced phenotype switch of microglia in vitro

(2012) I. Gerhauser et al.   JOURNAL OF NEUROIMMUNOLOGY

Interleukin-10 expression during the acute phase is a putative prerequisite for delayed viral elimination in a murine model for multiple sclerosis

(2012) Vanessa Herder et al.   JOURNAL OF NEUROIMMUNOLOGY

Inflammatory Mediators Alter the Astrocyte Transcriptome and Calcium Signaling Elicited by Multiple G-Protein-Coupled Receptors

(2012) M. E. Hamby et al.   JOURNAL OF NEUROSCIENCE

Signal transducer and activator of transcription-3/suppressor of cytokine signaling-3 (STAT3/SOCS3) axis in myeloid cells regulates neuroinflammation

(2012) H. Qin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Viral models of multiple sclerosis: Neurodegeneration and demyelination in mice infected with Theiler's virus

(2012) Miriam Mecha et al.   PROGRESS IN NEUROBIOLOGY

Axonopathy Is Associated with Complex Axonal Transport Defects in a Model of Multiple Sclerosis

(2011) Mihaela Kreutzer et al.   BRAIN PATHOLOGY

Distinct Spatio-Temporal Extracellular Matrix Accumulation within Demyelinated Spinal Cord Lesions in Theiler's Murine Encephalomyelitis

(2011) Verena Haist et al.   BRAIN PATHOLOGY

Prominent Microglial Activation in the Early Proinflammatory Immune Response in Naturally Occurring Canine Spinal Cord Injury

(2011) Ingo Spitzbarth et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Repertoire of microglial and macrophage responses after spinal cord injury

(2011) Samuel David et al.   NATURE REVIEWS NEUROSCIENCE

Characterisation of microglia during de- and remyelination: Can they create a repair promoting environment?

(2011) Elke Verena Voß et al.   NEUROBIOLOGY OF DISEASE

Spatial and Temporal Profiles of Growth Factor Expression during CNS Demyelination Reveal the Dynamics of Repair Priming

(2011) Viktoria Gudi et al.   PLoS One

Viral triggers of multiple sclerosis

(2010) Kristina Kakalacheva et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

CNS-Resident Glial Progenitor/Stem Cells Produce Schwann Cells as well as Oligodendrocytes during Repair of CNS Demyelination

(2010) Malgorzata Zawadzka et al.   Cell Stem Cell

Regional topographical differences of canine microglial immunophenotype and function in the healthy spinal cord

(2010) Eva-Maria Ensinger et al.   JOURNAL OF NEUROIMMUNOLOGY

Altered M1/M2 activation patterns of monocytes in severe relapsing experimental rat model of multiple sclerosis. Amelioration of clinical status by M2 activated monocyte administration

(2010) Joanna Mikita et al.   Multiple Sclerosis Journal

Beneficial Effects of Minocycline on Cuprizone Induced Cortical Demyelination

(2010) Thomas Skripuletz et al.   NEUROCHEMICAL RESEARCH

Macrophages and Inflammatory Mediators in Chemical Toxicity: A Battle of Forces

(2009) Debra L. Laskin   CHEMICAL RESEARCH IN TOXICOLOGY

Machine learning approach identifies new pathways associated with demyelination in a viral model of multiple sclerosis

(2009) Reiner Ulrich et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Th17 cells enhance viral persistence and inhibit T cell cytotoxicity in a model of chronic virus infection

(2009) Wanqiu Hou et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Ym1/2 Promotes Th2 Cytokine Expression by Inhibiting 12/15(S)-Lipoxygenase: Identification of a Novel Pathway for Regulating Allergic Inflammation

(2009) Y. Cai et al.   JOURNAL OF IMMUNOLOGY

Role of the innate immune system in the pathogenesis of multiple sclerosis

(2009) Roopali Gandhi et al.   JOURNAL OF NEUROIMMUNOLOGY

Identification of Two Distinct Macrophage Subsets with Divergent Effects Causing either Neurotoxicity or Regeneration in the Injured Mouse Spinal Cord

(2009) K. A. Kigerl et al.   JOURNAL OF NEUROSCIENCE

Generation and characterization of a polyclonal antibody for the detection of Theiler's murine encephalomyelitis virus by light and electron microscopy

(2009) Maren Kummerfeld et al.   JOURNAL OF VIROLOGICAL METHODS

Axonal degeneration as a self-destructive defense mechanism against neurotropic virus infection

(2008) Ikuo Tsunoda   Future Virology

Myelin-induced microglial neurotoxicity can be controlled by microglial metabotropic glutamate receptors

(2008) Fleur Pinteaux-Jones et al.   JOURNAL OF NEUROCHEMISTRY

Differential transcription of matrix-metalloproteinase genes in primary mouse astrocytes and microglia infected with Theiler's murine encephalomyelitis virus

(2008) Jirawat Kumnok et al.   JOURNAL OF NEUROVIROLOGY

Multiple sclerosis

(2008) Alastair Compston et al.   LANCET

Axon regeneration inhibitors

(2008) Lynda J.-S. Yang et al.   NEUROLOGICAL RESEARCH

Limited remyelination in Theiler's murine encephalomyelitis due to insufficient oligodendroglial differentiation of nerve/glial antigen 2 (NG2)-positive putative oligodendroglial progenitor cells

(2008) R. Ulrich et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Immunophenotypical characterization of monocytes in canine distemper virus infection

(2008) Veronika M. Stein et al.   VETERINARY MICROBIOLOGY

Increase of Pro-Inflammatory Cytokine Expression in Non-Demyelinating Early Cerebral Lesions in Nervous Canine Distemper

(2008) Andreas Beineke et al.   VIRAL IMMUNOLOGY