ZEB1 Promotes Invasion in Human Fetal Neural Stem Cells and Hypoxic Glioma Neurospheres

LIN28A facilitates the transformation of human neural stem cells and promotes glioblastoma tumorigenesis through a pro-invasive genetic program

(2015) Xing-gang Mao et al.   Oncotarget

CXCR7 is induced by hypoxia and mediates glioma cell migration towards SDF-1α

(2013) Mine Esencay et al.   BMC CANCER

Poised Chromatin at the ZEB1 Promoter Enables Breast Cancer Cell Plasticity and Enhances Tumorigenicity

(2013) Christine L. Chaffer et al.   CELL

The EMT activator ZEB1 promotes tumor growth and determines differential response to chemotherapy in mantle cell lymphoma

(2013) E Sánchez-Tilló et al.   CELL DEATH AND DIFFERENTIATION

The ZEB1 pathway links glioblastoma initiation, invasion and chemoresistance

(2013) Florian A. Siebzehnrubl et al.   EMBO Molecular Medicine

Geranylgeranyltransferase I regulates HIF-1α promoting glioblastoma cell migration and invasion

(2013) Xiuping Zhou et al.   JOURNAL OF NEURO-ONCOLOGY

Sustained elevation of Snail promotes glial-mesenchymal transition after irradiation in malignant glioma

(2013) Roshan Mahabir et al.   NEURO-ONCOLOGY

Snail depletes the tumorigenic potential of glioblastoma

(2013) K Savary et al.   ONCOGENE

The “go or grow” potential of gliomas is linked to the neuropeptide processing enzyme carboxypeptidase E and mediated by metabolic stress

(2012) Elisabeth Höring et al.   ACTA NEUROPATHOLOGICA

Transcriptional Factors for Epithelial-Mesenchymal Transition Are Associated with Mesenchymal Differentiation in Gliosarcoma

(2012) Masaya Nagaishi et al.   BRAIN PATHOLOGY

Activation of canonical WNT/β-catenin signaling enhances in vitro motility of glioblastoma cells by activation of ZEB1 and other activators of epithelial-to-mesenchymal transition

(2012) Ulf D. Kahlert et al.   CANCER LETTERS

Epithelial-to-mesenchymal(-like) transition as a relevant molecular event in malignant gliomas

(2012) U.D. Kahlert et al.   CANCER LETTERS

ZEB/miR-200 feedback loop: At the crossroads of signal transduction in cancer

(2012) Louise Hill et al.   INTERNATIONAL JOURNAL OF CANCER

Induction of ZEB Proteins by Inactivation of RB Protein Is Key Determinant of Mesenchymal Phenotype of Breast Cancer

(2012) Yoshimi Arima et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Resistance to Hypoxia-Induced, BNIP3-Mediated Cell Death Contributes to an Increase in a CD133-Positive Cell Population in Human Glioblastomas In Vitro

(2012) Ulf Dietrich Kahlert et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Function of carbonic anhydrase IX in glioblastoma multiforme

(2012) M. A. Proescholdt et al.   NEURO-ONCOLOGY

VHL regulates the effects of miR-23b on glioma survival and invasion via suppression of HIF-1α/VEGF and β-catenin/Tcf-4 signaling

(2012) Lingchao Chen et al.   NEURO-ONCOLOGY

Effect of silencing HIF-1α on proliferation, invasion and migration of glioblastoma U87 cells

(2012) S. H. Shen et al.   NEUROLOGICAL SCIENCES

SNAI1 is Involved in the Proliferation and Migration of Glioblastoma Cells

(2011) Sung-Pil Han et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

An autocrine TGF-β/ZEB/miR-200 signaling network regulates establishment and maintenance of epithelial-mesenchymal transition

(2011) Philip A. Gregory et al.   MOLECULAR BIOLOGY OF THE CELL

Mouse Snail Is a Target Gene for HIF

(2011) D. Luo et al.   MOLECULAR CANCER RESEARCH

p53 regulates epithelial–mesenchymal transition and stem cell properties through modulating miRNAs

(2011) Chun-Ju Chang et al.   NATURE CELL BIOLOGY

 -catenin/TCF4 complex induces the epithelial-to-mesenchymal transition (EMT)-activator ZEB1 to regulate tumor invasiveness

(2011) E. Sanchez-Tillo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular diagnostics of gliomas: the clinical perspective

(2010) Ghazaleh Tabatabai et al.   ACTA NEUROPATHOLOGICA

Hypoxia Increases the Expression of Stem-Cell Markers and Promotes Clonogenicity in Glioblastoma Neurospheres

(2010) Eli E. Bar et al.   AMERICAN JOURNAL OF PATHOLOGY

Glioblastoma, Cancer Stem Cells and Hypoxia

(2010) Eli E. Bar   BRAIN PATHOLOGY

Oxygen in Stem Cell Biology: A Critical Component of the Stem Cell Niche

(2010) Ahmed Mohyeldin et al.   Cell Stem Cell

'Go or Grow': the key to the emergence of invasion in tumour progression?

(2010) H. Hatzikirou et al.   MATHEMATICAL MEDICINE AND BIOLOGY-A JOURNAL OF THE IMA

Knock down of HIF-1α in glioma cells reduces migration in vitro and invasion in vivo and impairs their ability to form tumor spheres

(2010) Olga Méndez et al.   Molecular Cancer

TWIST1 promotes invasion through mesenchymal change in human glioblastoma

(2010) Svetlana A Mikheeva et al.   Molecular Cancer

Hypoxia-Inducible Factors Regulate Tumorigenic Capacity of Glioma Stem Cells

(2009) Zhizhong Li et al.   CANCER CELL

Antiangiogenic Therapy Elicits Malignant Progression of Tumors to Increased Local Invasion and Distant Metastasis

(2009) Marta Pàez-Ribes et al.   CANCER CELL

Downregulation of miRNA-200c Links Breast Cancer Stem Cells with Normal Stem Cells

(2009) Yohei Shimono et al.   CELL

Epithelial-Mesenchymal Transitions in Development and Disease

(2009) Jean Paul Thiery et al.   CELL

The basics of epithelial-mesenchymal transition

(2009) Raghu Kalluri et al.   JOURNAL OF CLINICAL INVESTIGATION

Transcription factor Sp1 induces ADAM17 and contributes to tumor cell invasiveness under hypoxia

(2009) Alexandra Szalad et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Brain tumor hypoxia: tumorigenesis, angiogenesis, imaging, pseudoprogression, and as a therapeutic target

(2009) Randy L. Jensen   JOURNAL OF NEURO-ONCOLOGY

The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs

(2009) Ulrich Wellner et al.   NATURE CELL BIOLOGY

Inhibition of tissue factor/protease-activated receptor-2 signaling limits proliferation, migration and invasion of malignant glioma cells

(2009) F. Gessler et al.   NEUROSCIENCE

The Transcriptional Repressor ZEB1 Promotes Metastasis and Loss of Cell Polarity in Cancer

(2008) S. Spaderna et al.   CANCER RESEARCH

The miR-200 Family Inhibits Epithelial-Mesenchymal Transition and Cancer Cell Migration by Direct Targeting of E-cadherin Transcriptional RepressorsZEB1andZEB2

(2008) Manav Korpal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Direct regulation of TWIST by HIF-1α promotes metastasis

(2008) Muh-Hwa Yang et al.   NATURE CELL BIOLOGY

Digoxin and other cardiac glycosides inhibit HIF-1  synthesis and block tumor growth

(2008) H. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA