T cell markers recount the course of immunosenescence in healthy individuals and chronic kidney disease

A very low thymus function identifies patients with substantial increased risk for long-term mortality after kidney transplantation

(2020) Michiel G. H. Betjes et al.   Immunity & Ageing

Biological Aging and Immune Senescence in Children with Perinatally Acquired HIV

(2020) Annalisa Dalzini et al.   Journal of Immunology Research

Influence of end stage renal disease on CD28 expression and T‐cell immunity

(2020) Erasmia Sampani et al.   NEPHROLOGY

Kidney Failure Associates With T Cell Exhaustion and Imbalanced Follicular Helper T Cells

(2020) Susan Hartzell et al.   Frontiers in Immunology

Effect of Type of Dialysis on CMV-Specific CD8+ T Cells in Kidney Transplant Candidates

(2019) Jose Ramón Vidal-Castiñeira et al.   Frontiers in Immunology

Inducible T‐cell co‐stimulator: Signaling mechanisms in T follicular helper cells and beyond

(2019) Vincent Panneton et al.   IMMUNOLOGICAL REVIEWS

The difference of T cell phenotypes in end stage renal disease patients under different dialysis modality

(2019) Jiao Xiaoyan et al.   BMC Nephrology

End-Stage Renal Disease-Associated Gut Bacterial Translocation: Evolution and Impact on Chronic Inflammation and Acute Rejection After Renal Transplantation

(2019) Clémence Carron et al.   Frontiers in Immunology

CD28 and CD57 define four populations with distinct phenotypic properties within human CD8 + T cells

(2019) Luca Pangrazzi et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

End-stage renal disease, dialysis, kidney transplantation and their impact on CD4+ T-cell differentiation

(2018) Matthias Schaier et al.   IMMUNOLOGY

CD45 in human physiology and clinical medicine

(2018) Andreas Rheinländer et al.   IMMUNOLOGY LETTERS

ESRD-associated immune phenotype depends on dialysis modality and iron status: clinical implications

(2018) Didier Ducloux et al.   Immunity & Ageing

Frontline Science: PECAM-1 (CD31) expression in naïve and memory, but not acutely activated, CD8+ T cells

(2018) Debra K. Newman et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Human CD8+ CD57- TEMRA cells: Too young to be called "old"

(2017) Kriti Verma et al.   PLoS One

Phenotypic characteristics of aged CD4+ CD28null T lymphocytes are determined by changes in the whole-genome DNA methylation pattern

(2016) Beatriz Suarez-Álvarez et al.   AGING CELL

Aging of the immune system: Focus on inflammation and vaccination

(2016) Marcello Pinti et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Premature T Cell Senescence in Pediatric CKD

(2016) Roshan P. George et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Intestinal Dysbiosis, Barrier Dysfunction, and Bacterial Translocation Account for CKD–Related Systemic Inflammation

(2016) Kirstin Andersen et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Blockade of PD-1 or p38 MAP kinase signaling enhances senescent human CD8+T-cell proliferation by distinct pathways

(2015) Sian M. Henson et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

T cell metabolism drives immunity

(2015) Michael D. Buck et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Gut Microbial Translocation in the Pathogenesis of Systemic Inflammation in Patients with End-Stage Renal Disease

(2014) Nosratola D. Vaziri   DIGESTIVE DISEASES AND SCIENCES

p38 signaling inhibits mTORC1-independent autophagy in senescent human CD8+ T cells

(2014) Sian M. Henson et al.   JOURNAL OF CLINICAL INVESTIGATION

Homeostasis of the Naive CD4+ T Cell Compartment during Aging

(2014) R. D. Kilpatrick et al.   JOURNAL OF IMMUNOLOGY

The Hallmarks of Aging

(2013) Carlos López-Otín et al.   CELL

Cellular senescence and the senescent secretory phenotype: therapeutic opportunities

(2013) Tamara Tchkonia et al.   JOURNAL OF CLINICAL INVESTIGATION

IFN-  Inhibits Telomerase in Human CD8+ T Cells by Both hTERT Downregulation and Induction of p38 MAPK Signaling

(2013) A. Lanna et al.   JOURNAL OF IMMUNOLOGY

Regulation of Immune Responses by mTOR

(2012) Jonathan D. Powell et al.   Annual Review of Immunology

Inflamm-ageing

(2012) Elisa Cevenini et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Uremia causes premature ageing of the T cell compartment in end-stage renal disease patients

(2012) Ruud WJ Meijers et al.   Immunity & Ageing

Increased interleukin-17 producing effector memory T cells in the end-stage renal disease patients

(2011) Byung Ha Chung et al.   IMMUNOLOGY LETTERS

Reversible Senescence in Human CD4+CD45RA+CD27- Memory T Cells

(2011) D. Di Mitri et al.   JOURNAL OF IMMUNOLOGY

Premature aging of circulating T cells in patients with end-stage renal disease

(2011) Michiel G.H. Betjes et al.   KIDNEY INTERNATIONAL

Intestinal CD103+ dendritic cells: master regulators of tolerance?

(2011) Charlotte L. Scott et al.   TRENDS IN IMMUNOLOGY

The Aging Kidney: Physiological Changes

(2010) Jessica R. Weinstein et al.   ADVANCES IN CHRONIC KIDNEY DISEASE

Subsets of CD8 +, CD57+ cells in normal, healthy individuals: correlations with human cytomegalovirus (HCMV) carrier status, phenotypic and functional analyses

(2010) E. C. Y. WANG et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Circulating Endotoxemia: A Novel Factor in Systemic Inflammation and Cardiovascular Disease in Chronic Kidney Disease

(2010) C. W. McIntyre et al.   Clinical Journal of the American Society of Nephrology

The essence of senescence

(2010) T. Kuilman et al.   GENES & DEVELOPMENT

Overview of the immune response

(2010) David D. Chaplin   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Prolonged CD4 T Cell Lymphopenia Increases Morbidity and Mortality after Renal Transplantation

(2010) D. Ducloux et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Role of CMV in immune senescence

(2010) Graham Pawelec et al.   VIRUS RESEARCH

DNA damage response and cellular senescence in tissues of aging mice

(2009) Chunfang Wang et al.   AGING CELL

Rate of Kidney Function Decline in Older Adults: A Comparison Using Creatinine and Cystatin C

(2009) Michael G. Shlipak et al.   AMERICAN JOURNAL OF NEPHROLOGY

KLRG1 signaling induces defective Akt (ser473) phosphorylation and proliferative dysfunction of highly differentiated CD8+ T cells

(2009) S. M. Henson et al.   BLOOD

Characteristics of Expanded CD4+CD28nullT Cells in Patients with Chronic Hepatitis B

(2009) Yiqin Wang et al.   IMMUNOLOGICAL INVESTIGATIONS

Molecular Basis for E-cadherin Recognition by Killer Cell Lectin-like Receptor G1 (KLRG1)

(2009) Seiko Nakamura et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Evidence of premature immune aging in patients thymectomized during early childhood

(2009) Delphine Sauce et al.   JOURNAL OF CLINICAL INVESTIGATION

Human CD4+T cell recent thymic emigrants are identified by protein tyrosine kinase 7 and have reduced immune function

(2009) Christopher J. Haines et al.   JOURNAL OF EXPERIMENTAL MEDICINE

CD57+ T lymphocytes and functional immune deficiency

(2009) Daniele Focosi et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Effect of ageing on CMV-specific CD8 T cells from CMV seropositive healthy donors

(2009) María Pita-Lopez et al.   Immunity & Ageing

Life after the thymus: CD31+ and CD31- human naive CD4+ T-cell subsets

(2008) S. Kohler et al.   BLOOD

Thymectomy in early childhood: Significant alterations of the CD4+CD45RA+CD62L+ T cell compartment in later life

(2008) Martina Prelog et al.   CLINICAL IMMUNOLOGY

Homeostasis of Naive and Memory T Cells

(2008) Charles D. Surh et al.   IMMUNITY

Neopterin, CD4+CD28− lymphocytes and the extent and severity of coronary artery disease

(2008) Hannes F. Alber et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Inflammation, T-Cell Phenotype, and Inflammatory Cytokines in Chronic Kidney Disease Patients Under Hemodialysis and its Relationship to Resistance to Recombinant Human Erythropoietin Therapy

(2008) Elísio Costa et al.   JOURNAL OF CLINICAL IMMUNOLOGY