Phenotypic characteristics of aged CD4+ CD28null T lymphocytes are determined by changes in the whole-genome DNA methylation pattern

Age-dependent expression ofDNMT1andDNMT3Bin PBMCs from a large European population enrolled in the MARK-AGE study

(2016) Fabio Ciccarone et al.   AGING CELL

Cytomegalovirus-Associated CD4+CD28nullCells in NKG2D-Dependent Glomerular Endothelial Injury and Kidney Allograft Dysfunction

(2016) S. Shabir et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Epigenetic profiling in CD4+ and CD8+ T cells from Graves' disease patients reveals changes in genes associated with T cell receptor signaling

(2016) Maia Limbach et al.   JOURNAL OF AUTOIMMUNITY

Age-associated epigenetic modifications in human DNA increase its immunogenicity

(2016) Anshu Agrawal et al.   Aging-US

DNA Methylation Regulates the Differential Expression of CX3CR1 on Human IL-7Rαlowand IL-7RαhighEffector Memory CD8+T Cells with Distinct Migratory Capacities to the Fractalkine

(2015) Min Sun Shin et al.   JOURNAL OF IMMUNOLOGY

Defining CD4 T Cell Memory by the Epigenetic Landscape of CpG DNA Methylation

(2015) H. Kiyomi Komori et al.   JOURNAL OF IMMUNOLOGY

Aging and epigenetic drift: a vicious cycle

(2014) Jean-Pierre Issa   JOURNAL OF CLINICAL INVESTIGATION

Regulation of the transcriptional program by DNA methylation during human αβ T-cell development

(2014) Ramon M. Rodriguez et al.   NUCLEIC ACIDS RESEARCH

Differential affinity of FLIP and procaspase 8 for FADD’s DED binding surfaces regulates DISC assembly

(2014) J. Majkut et al.   Nature Communications

Characterization of CD4+CD28null T cells in patients with coronary artery disease and individuals with risk factors for atherosclerosis

(2013) Fábio Haach Téo et al.   CELLULAR IMMUNOLOGY

Epigenetic modulation of the immune function

(2013) Beatriz Suárez-Álvarez et al.   Epigenetics

Cross-sectional and longitudinal changes in DNA methylation with age: an epigenome-wide analysis revealing over 60 novel age-associated CpG sites

(2013) I. Florath et al.   HUMAN MOLECULAR GENETICS

DAP12 impacts trafficking and surface stability of killer immunoglobulin-like receptors on natural killer cells

(2013) Tiernan J. Mulrooney et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Cell death by pyroptosis drives CD4 T-cell depletion in HIV-1 infection

(2013) Gilad Doitsh et al.   NATURE

Apoptotic Effects of Antilymphocyte Globulins on Human Pro-inflammatory CD4+CD28− T-cells

(2012) Christina Duftner et al.   PLoS One

Distinct DNA methylomes of newborns and centenarians

(2012) H. Heyn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

DNA methylation: a promising landscape for immune system-related diseases

(2012) Beatriz Suarez-Alvarez et al.   TRENDS IN GENETICS

Pathogenic features of CD4+CD28– T cells in immune disorders

(2012) Bieke Broux et al.   TRENDS IN MOLECULAR MEDICINE

Baseline Numbers of Circulating CD28-negative T Cells May Predict Clinical Response to Abatacept in Patients with Rheumatoid Arthritis

(2011) MIRKO SCARSI et al.   JOURNAL OF RHEUMATOLOGY

A promoter DNA demethylation landscape of human hematopoietic differentiation

(2011) Vincenzo Calvanese et al.   NUCLEIC ACIDS RESEARCH

Rosuvastatin induces apoptosis in CD4+CD28null T cells in patients with acute coronary syndromes

(2010) Andreas Link et al.   Clinical Research in Cardiology

Epigenetic regulation of killer immunoglobulin-like receptor expression in T cells

(2009) G. Li et al.   BLOOD

KLRG1 signaling induces defective Akt (ser473) phosphorylation and proliferative dysfunction of highly differentiated CD8+ T cells

(2009) S. M. Henson et al.   BLOOD

Decreased DNA methyltransferase levels contribute to abnormal gene expression in “senescent” CD4+CD28− T cells

(2009) Ying Liu et al.   CLINICAL IMMUNOLOGY

The T-cell-receptor signaling network

(2009) M. Huse   JOURNAL OF CELL SCIENCE

Runx3 and T-box proteins cooperate to establish the transcriptional program of effector CTLs

(2009) Fernando Cruz-Guilloty et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Functional Killer Ig-Like Receptors on Human Memory CD4+ T Cells Specific for Cytomegalovirus

(2009) J. van Bergen et al.   JOURNAL OF IMMUNOLOGY

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

CD28− T cells: their role in the age-associated decline of immune function

(2009) Nan-ping Weng et al.   TRENDS IN IMMUNOLOGY

lumi: a pipeline for processing Illumina microarray

(2008) P. Du et al.   BIOINFORMATICS