Shape matters: Morphologically biomimetic particles for improved drug delivery

Engine-Trailer-Structured Nanotrucks for Efficient Nano-Bio Interactions and Bioimaging-Guided Drug Delivery

(2020) Wenxing Wang et al.   Chem

Biomimetic Rebuilding of Multifunctional Red Blood Cells: Modular Design Using Functional Components

(2020) Jimin Guo et al.   ACS Nano

Reverse design of an influenza neutralizing spiky nano‐inhibitor with a dual mode of action

(2020) Chuanxiong Nie et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Engineering the drug carrier biointerface to overcome biological barriers to drug delivery

(2020) Joel A. Finbloom et al.   ADVANCED DRUG DELIVERY REVIEWS

Spiky Nanostructures with Geometry-matching Topography for Virus Inhibition

(2020) Chuanxiong Nie et al.   NANO LETTERS

Rational design of a multi-valent human papillomavirus vaccine by capsomere-hybrid co-assembly of virus-like particles

(2020) Daning Wang et al.   Nature Communications

Tailoring Viruslike Mesoporous FeSe2 Hedgehogs for Controlled Drug Delivery and Synergistic Tumor Suppression

(2020) Jie Wang et al.   ACS Applied Materials & Interfaces

Recent advances in duplex-specific nuclease-based signal amplification strategies for microRNA detection

(2020) Yudong Wu et al.   BIOSENSORS & BIOELECTRONICS

Cancer Immunotherapy via Targeting Cancer Stem Cells Using Vaccine Nanodiscs

(2020) Alireza Hassani Najafabadi et al.   NANO LETTERS

Delivery technologies for cancer immunotherapy

(2019) Rachel S. Riley et al.   NATURE REVIEWS DRUG DISCOVERY

Injectable Slippery Lubricant-Coated Spiky Microparticles with Persistent and Exceptional Biofouling-Resistance

(2019) Chengduan Yang et al.   ACS Central Science

Light-driven synthesis of uniform dandelion-like mesoporous silica nanoflowers with tunable surface area for carbon dioxide uptake

(2019) Sankar Das et al.   CHEMICAL ENGINEERING JOURNAL

Role of Nanoparticle Mechanical Properties in Cancer Drug Delivery

(2019) Yue Hui et al.   ACS Nano

Application of Förster Resonance Energy Transfer (FRET) technique to elucidate intracellular and In Vivo biofate of nanomedicines

(2019) Tongkai Chen et al.   ADVANCED DRUG DELIVERY REVIEWS

An update on synthetic high-density lipoprotein-like nanoparticles for cancer therapy

(2019) Stephen E. Henrich et al.   Expert Review of Anticancer Therapy

Supramolecular Assembly of High-Density Lipoprotein Mimetic Nanoparticles Using Lipid-Conjugated Core Scaffolds

(2019) Stephen E. Henrich et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Functionalized Spiky Particles for Intracellular Biomolecular Delivery

(2019) Hui-Jiuan Chen et al.   ACS Central Science

Artificial High Density Lipoprotein Nanoparticles in Cardiovascular Research

(2019) Kornmueller et al.   MOLECULES

Nanoparticle Size Influences Antigen Retention and Presentation in Lymph Node Follicles for Humoral Immunity

(2019) Yi-Nan Zhang et al.   NANO LETTERS

Inorganic Nanozyme with Combined Self-Oxygenation/Degradable Capabilities for Sensitized Cancer Immunochemotherapy

(2019) Jie Wang et al.   Nano-Micro Letters

Morphology-Tailored Gold Nanoraspberries Based on Seed-Mediated Space-Confined Self-Assembly

(2019) Yan Yu et al.   Nanomaterials

Dandelion‐Like Tailorable Nanoparticles for Tumor Microenvironment Modulation

(2019) Qin Guo et al.   Advanced Science

Targeting the Cell Membrane by Charge-Reversal Amphiphilic Pillar[5]arene for the Selective Killing of Cancer Cells

(2019) Yincheng Chang et al.   ACS Applied Materials & Interfaces

Tumor Microenvironment Responsive Shape-Reversal Self-Targeting Virus-Inspired Nanodrug for Imaging-Guided Near-Infrared-II Photothermal Chemotherapy

(2019) Yang Li et al.   ACS Nano

Synthetic high-density lipoprotein nanoparticles for the treatment of Niemann–Pick diseases

(2019) Mark L. Schultz et al.   BMC Medicine

Highly efficient dandelion-like near-infrared light photoinitiator for free radical and thiol-ene photopolymerizations

(2019) Zhiquan Li et al.   Nature Communications

Design of a Novel Oxygen Therapeutic Using Polymeric Hydrogel Microcapsules Mimicking Red Blood Cells

(2019) Amanda Cherwin et al.   Pharmaceutics

Self-Assembly of Chiral Nanoparticles into Semiconductor Helices with Tunable near-Infrared Optical Activity

(2019) Jiao Yan et al.   CHEMISTRY OF MATERIALS

Targeted Nanoparticle-Mediated Gene Therapy Mimics Oncolytic Virus for Effective Melanoma Treatment

(2018) Li Luo et al.   ADVANCED FUNCTIONAL MATERIALS

Red Blood Cells as Smart Delivery Systems

(2018) Xiao Han et al.   BIOCONJUGATE CHEMISTRY

Red blood cell-like particles with the ability to avoid lung and spleen accumulation for the treatment of liver fibrosis

(2018) Koichiro Hayashi et al.   BIOMATERIALS

Cellulose-based molecularly imprinted red-blood-cell-like microparticles for the selective capture of cortisol

(2018) Koichiro Hayashi et al.   CARBOHYDRATE POLYMERS

Size shrinkable drug delivery nanosystems and priming the tumor microenvironment for deep intratumoral penetration of nanoparticles

(2018) Yimin Niu et al.   JOURNAL OF CONTROLLED RELEASE

Omnidispersible Hedgehog Particles with Multilayer Coatings for Multiplexed Biosensing

(2018) Douglas G. Montjoy et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cauliflower-like hierarchical silicalite-1 supported AuNPs toward improved catalytic reduction of p-nitrophenol

(2018) Rituparna Das et al.   NEW JOURNAL OF CHEMISTRY

High density lipoprotein cholesterol and cancer: Marker or causative?

(2018) Matteo Pirro et al.   PROGRESS IN LIPID RESEARCH

Study on the formation and properties of red blood cell-like Fe3O4/TbLa3(Bim)12/PLGA composite particles

(2018) Ping Li et al.   RSC Advances

Red Blood Cell-Shaped Microparticles with a Red Blood Cell Membrane Demonstrate Prolonged Circulation Time in Blood

(2018) Koichiro Hayashi et al.   ACS Biomaterials-Science & Engineering

Red Blood Cell-Shaped Microparticles with a Red Blood Cell Membrane Demonstrate Prolonged Circulation Time in Blood

(2018) Koichiro Hayashi et al.   ACS Biomaterials Science & Engineering

Cell membrane-based nanoparticles: a new biomimetic platform for tumor diagnosis and treatment

(2018) Ruixiang Li et al.   Acta Pharmaceutica Sinica B

Use of plant viruses and virus-like particles for the creation of novel vaccines

(2018) Ina Balke et al.   ADVANCED DRUG DELIVERY REVIEWS

Unexpected stability of aqueous dispersions of raspberry-like colloids

(2018) Yang Lan et al.   Nature Communications

Nanospikes-mediated Anomalous Dispersities of Hydropobic Micro-objects and their Application for Oil Emulsion Cleaning

(2018) Hui-Jiuan Chen et al.   Scientific Reports

Reconstituted Discoidal High-Density Lipoproteins: Bioinspired Nanodiscs with Many Unexpected Applications

(2018) Maki Tsujita et al.   Current Atherosclerosis Reports

A separated vortex ring underlies the flight of the dandelion

(2018) Cathal Cummins et al.   NATURE

Physical activation of innate immunity by spiky particles

(2018) Ji Wang et al.   Nature Nanotechnology

Worm-Like Biomimetic Nanoerythrocyte Carrying siRNA for Melanoma Gene Therapy

(2018) Yanming Wang et al.   Small

Biomimetic surface modification of discoidal polymeric particles

(2018) Tuyen Duong Thanh Nguyen et al.   Nanomedicine-Nanotechnology Biology and Medicine

Template-Free Hierarchical Self-Assembly of Iron Diselenide Nanoparticles into Mesoscale Hedgehogs

(2017) Dawei Deng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nanoengineering of Core–Shell Magnetic Mesoporous Microspheres with Tunable Surface Roughness

(2017) Qin Yue et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Biocompatible β-SrHPO 4 clusters with dandelion-like structure as an alternative drug carrier

(2017) Haishan Shi et al.   Materials Science & Engineering C-Materials for Biological Applications

Effect of size and pegylation of liposomes and peptide-based synthetic lipoproteins on tumor targeting

(2017) Jie Tang et al.   Nanomedicine-Nanotechnology Biology and Medicine

The evolving landscape of drug products containing nanomaterials in the United States

(2017) Sheetal R. D'Mello et al.   Nature Nanotechnology

Influence of nanoparticle shapes on cellular uptake of paclitaxel loaded nanoparticles in 2D and 3D cancer models

(2017) Jiacheng Zhao et al.   Polymer Chemistry

Synthesis of hierarchical flower-like particles and its application as super-hydrophobic coating

(2017) Xinzhi Wang et al.   POWDER TECHNOLOGY

Lipoprotein-biomimetic nanostructure enables efficient targeting delivery of siRNA to Ras-activated glioblastoma cells via macropinocytosis

(2017) Jia-Lin Huang et al.   Nature Communications

Facile Synthesis of Uniform Virus-like Mesoporous Silica Nanoparticles for Enhanced Cellular Internalization

(2017) Wenxing Wang et al.   ACS Central Science

Cell membrane-coated nanoparticles for tumor-targeted drug delivery

(2017) Zhilan Chai et al.   Science China-Materials

Assembly of mesoscale helices with near-unity enantiomeric excess and light-matter interactions for chiral semiconductors

(2017) Wenchun Feng et al.   Science Advances

Biointerfacing and Applications of Cell Membrane-Coated Nanoparticles

(2016) Ashley V. Kroll et al.   BIOCONJUGATE CHEMISTRY

Novel synthesis of AB-type carbonated hydroxyapatite hierarchical microstructures with sustained drug delivery properties

(2016) Ruixue Sun et al.   CRYSTENGCOMM

Sustainable Nanotechnology: Opportunities and Challenges for Theoretical/Computational Studies

(2016) Qiang Cui et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Silica Nanopollens Enhance Adhesion for Long-Term Bacterial Inhibition

(2016) Hao Song et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ligand Controlled Morphology Evolution of Active Intermediates for the Syntheses of Gold Nanostars

(2016) Xianghua Meng et al.   LANGMUIR

Self-assembly of nanoparticles into biomimetic capsid-like nanoshells

(2016) Ming Yang et al.   Nature Chemistry

Designer vaccine nanodiscs for personalized cancer immunotherapy

(2016) Rui Kuai et al.   NATURE MATERIALS

Large-Scale Synthesis of Monodisperse Red Blood Cell (RBC)-Like Polymer Particles

(2016) Delong Xie et al.   ACS Macro Letters

The Role of Surface Nanotopography and Chemistry on Primary Neutrophil and Macrophage Cellular Responses

(2016) Susan N. Christo et al.   Advanced Healthcare Materials

Cancer Cell Internalization of Gold Nanostars Impacts Their Photothermal Efficiency In Vitro and In Vivo: Toward a Plasmonic Thermal Fingerprint in Tumoral Environment

(2016) Ana Espinosa et al.   Advanced Healthcare Materials

Elasticity of Nanoparticles Influences Their Blood Circulation, Phagocytosis, Endocytosis, and Targeting

(2015) Aaron C. Anselmo et al.   ACS Nano

Size-dependent nanoparticulate drug delivery in inflammatory bowel diseases

(2015) John Youshia et al.   Expert Opinion on Drug Delivery

Cell membrane-camouflaged nanoparticles for drug delivery

(2015) Brian T. Luk et al.   JOURNAL OF CONTROLLED RELEASE

Shape effect in cellular uptake of PEGylated nanoparticles: comparison between sphere, rod, cube and disk

(2015) Ying Li et al.   Nanoscale

Anomalous dispersions of ‘hedgehog’ particles

(2015) Joong Hwan Bahng et al.   NATURE

Developing an aqueous approach for synthesizing Au and M@Au (M = Pd, CuPt) hybrid nanostars with plasmonic properties

(2015) Jingshan Du et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

On the Origin and Underappreciated Effects of Ion Doping in Silica

(2015) Xiaohui Song et al.   Small

Novel red blood cell shaped α-Fe2O3 microstructures and FeO(OH) nanorods as high capacity supercapacitors

(2015) Rongmei Liu et al.   RSC Advances

Cell or Cell Membrane-Based Drug Delivery Systems

(2015) Songwei Tan et al.   Theranostics

Engineering Cellular Response Using Nanopatterned Bulk Metallic Glass

(2014) Jagannath Padmanabhan et al.   ACS Nano

Tunable Rigidity of (Polymeric Core)-(Lipid Shell) Nanoparticles for Regulated Cellular Uptake

(2014) Jiashu Sun et al.   ADVANCED MATERIALS

Colloidal RBC-Shaped, Hydrophilic, and Hollow Mesoporous Carbon Nanocapsules for Highly Efficient Biomedical Engineering

(2014) Yu Chen et al.   ADVANCED MATERIALS

Mechanically Encoded Cellular Shapes for Synthesis of Anisotropic Mesoporous Particles

(2014) Kristin C. Meyer et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Shape-Controlled Paclitaxel Nanoparticles with Multiple Morphologies: Rod-Shaped, Worm-Like, Spherical, and Fingerprint-Like

(2014) Yongjun Wang et al.   MOLECULAR PHARMACEUTICS

A Universal Law for Cell Uptake of One-Dimensional Nanomaterials

(2014) Xin Yi et al.   NANO LETTERS

Rationally synthesized five-fold twinned core–shell Pt3Ni@Rh nanopentagons, nanostars and nanopaddlewheels for selective reduction of a phenyl ring of phthalimide

(2014) Nguyen Tien Khi et al.   Nanoscale

A Novel Red-Blood-Cell-Shaped Pectin-Oligochitosan Hydrogel System

(2014) Jenna Nicole Harvestine et al.   PARTICLE & PARTICLE SYSTEMS CHARACTERIZATION

Synthetic fossilization of soft biological tissues and their shape-preserving transformation into silica or electron-conductive replicas

(2014) Jason L. Townson et al.   Nature Communications

Facile synthesis of self-assembled spherical and mesoporous dandelion capsules of ZnO: efficient carrier for DNA and anti-cancer drugs

(2014) Vijay Bhooshan Kumar et al.   Journal of Materials Chemistry B

Fabrication of Red-Blood-Cell-Like Polyelectrolyte Microcapsules and Their Deformation and Recovery Behavior Through a Microcapillary

(2013) Shupeng She et al.   ADVANCED MATERIALS

Scalable Manufacture of Built-to-Order Nanomedicine: Spray-Assisted Layer-by-Layer Functionalization of PRINT Nanoparticles

(2013) Stephen W. Morton et al.   ADVANCED MATERIALS

Nanoparticles Mimicking Viral Surface Topography for Enhanced Cellular Delivery

(2013) Yuting Niu et al.   ADVANCED MATERIALS

Synthetic Approaches to RBC Mimicry and Oxygen Carrier Systems

(2013) Christa L. Modery-Pawlowski et al.   BIOMACROMOLECULES

Factors controlling the pharmacokinetics, biodistribution and intratumoral penetration of nanoparticles

(2013) Mark J. Ernsting et al.   JOURNAL OF CONTROLLED RELEASE

Silver Nanostars with High SERS Performance

(2013) Adianez Garcia-Leis et al.   Journal of Physical Chemistry C

Colloidal Stability of Self-Assembled Monolayer-Coated Gold Nanoparticles: The Effects of Surface Compositional and Structural Heterogeneity

(2013) Rixiang Huang et al.   LANGMUIR

Role of Nanoparticle Geometry in Endocytosis: Laying Down to Stand Up

(2013) Changjin Huang et al.   NANO LETTERS

Shaping cancer nanomedicine: the effect of particle shape on the in vivo journey of nanoparticles

(2013) Randall Toy et al.   Nanomedicine

Polymerization-Induced Self-Assembly (PISA) – control over the morphology of nanoparticles for drug delivery applications

(2013) Bunyamin Karagoz et al.   Polymer Chemistry

Mammalian cells preferentially internalize hydrogel nanodiscs over nanorods and use shape-specific uptake mechanisms

(2013) R. Agarwal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biodegradable synthetic high-density lipoprotein nanoparticles for atherosclerosis

(2013) Sean Marrache et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tailored Design of Architecturally Controlled Pt Nanoparticles with Huge Surface Areas toward Superior Unsupported Pt Electrocatalysts

(2012) Liang Wang et al.   ACS Applied Materials & Interfaces

The Effect of Nanoparticle Size, Shape, and Surface Chemistry on Biological Systems

(2012) Alexandre Albanese et al.   Annual Review of Biomedical Engineering

Low Modulus Biomimetic Microgel Particles with High Loading of Hemoglobin

(2012) Kai Chen et al.   BIOMACROMOLECULES

Molecular modeling of the relationship between nanoparticle shape anisotropy and endocytosis kinetics

(2012) Ye Li et al.   BIOMATERIALS

Controlled hydrothermal synthesis and magnetic properties of three-dimensional FeSe2 rod clusters and microspheres

(2012) Weidong Shi et al.   CHEMICAL ENGINEERING JOURNAL

High-Quality CuInS2/ZnS Quantum Dots for In vitro and In vivo Bioimaging

(2012) Dawei Deng et al.   CHEMISTRY OF MATERIALS

The effect of particle size on the biodistribution of low-modulus hydrogel PRINT particles

(2012) Timothy J. Merkel et al.   JOURNAL OF CONTROLLED RELEASE

Sea urchin-like Ag–α-Fe2O3 nanocomposite microspheres: synthesis and gas sensing applications

(2012) Xijun Liu et al.   JOURNAL OF MATERIALS CHEMISTRY

Flame synthesis of 1-D complex metal oxide nanomaterials

(2012) Lili Cai et al.   PROCEEDINGS OF THE COMBUSTION INSTITUTE

Cellular complexity captured in durable silica biocomposites

(2012) B. Kaehr et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Aspect Ratio Determines the Quantity of Mesoporous Silica Nanoparticle Uptake by a Small GTPase-Dependent Macropinocytosis Mechanism

(2011) Huan Meng et al.   ACS Nano

Nanostars shine bright for you

(2011) Andrés Guerrero-Martínez et al.   CURRENT OPINION IN COLLOID & INTERFACE SCIENCE

Dandelion-like Fe3O4@CuTNPc hierarchical nanostructures as a magnetically separable visible-light photocatalyst

(2011) Zengcai Guo et al.   JOURNAL OF MATERIALS CHEMISTRY

Using mechanobiological mimicry of red blood cells to extend circulation times of hydrogel microparticles

(2011) T. J. Merkel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Erythrocyte membrane-camouflaged polymeric nanoparticles as a biomimetic delivery platform

(2011) C.-M. J. Hu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multistage nanoparticle delivery system for deep penetration into tumor tissue

(2011) C. Wong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Assembly of dandelion-like Au/PANI nanocomposites and their application as SERS nanosensors

(2010) Xiufang Wang et al.   BIOSENSORS & BIOELECTRONICS

Endosomal escape pathways for delivery of biologicals

(2010) Amir K. Varkouhi et al.   JOURNAL OF CONTROLLED RELEASE

Light Concentration at the Nanometer Scale

(2010) Ramón Alvarez-Puebla et al.   Journal of Physical Chemistry Letters

Generation of a Library of Particles Having Controlled Sizes and Shapes via the Mechanical Elongation of Master Templates

(2010) Yapei Wang et al.   LANGMUIR

Computer simulation of the translocation of nanoparticles with different shapes across a lipid bilayer

(2010) Kai Yang et al.   Nature Nanotechnology

Red blood cell-mimicking synthetic biomaterial particles

(2009) N. Doshi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nanoparticle therapeutics: an emerging treatment modality for cancer

(2008) Mark E. Davis et al.   NATURE REVIEWS DRUG DISCOVERY