NSDHL promotes triple-negative breast cancer metastasis through the TGFβ signaling pathway and cholesterol biosynthesis

Crystal structures of human NSDHL and development of its novel inhibitor with the potential to suppress EGFR activity

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NAD(P)-dependent steroid dehydrogenase-like is involved in breast cancer cell growth and metastasis

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CHILD syndrome: A modified pathogenesis-targeted therapeutic approach

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PHF5A Epigenetically Inhibits Apoptosis to Promote Breast Cancer Progression.

(2018) Yi-Zi Zheng et al.   CANCER RESEARCH

Characterization of PIK3CA and PIK3R1 somatic mutations in Chinese breast cancer patients

(2018) Li Chen et al.   Nature Communications

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(2018) Daniel T. Dibaba et al.   BREAST CANCER RESEARCH AND TREATMENT

Statin use and risk of contralateral breast cancer: a nationwide cohort study

(2018) Rikke Langballe et al.   BRITISH JOURNAL OF CANCER

Loss of TMEM126A promotes extracellular matrix remodeling, epithelial-to-mesenchymal transition, and breast cancer metastasis by regulating mitochondrial retrograde signaling

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Fatty acid synthase (FASN) as a therapeutic target in breast cancer

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Role of Runx2 in breast cancer-mediated bone metastasis

(2017) M. Vishal et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Cholesterol, Cholesterol-Lowering Medication Use, and Breast Cancer Outcome in the BIG 1-98 Study

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Identification of essential genes for cancer immunotherapy

(2017) Shashank J. Patel et al.   NATURE

The SigmaR1 chaperone drives breast and colorectal cancer cell migration by tuning SK3-dependent Ca2+ homeostasis

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The cholesterol metabolite 27 hydroxycholesterol facilitates breast cancer metastasis through its actions on immune cells

(2017) Amy E. Baek et al.   Nature Communications

Comparison of patterns and prognosis among distant metastatic breast cancer patients by age groups: a SEER population-based analysis

(2017) Meng-Ting Chen et al.   Scientific Reports

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EGFR and RB1 as Dual Biomarkers in HPV-Negative Head and Neck Cancer

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Targeting metastasis-initiating cells through the fatty acid receptor CD36

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Genome-wide CRISPR Screen in a Mouse Model of Tumor Growth and Metastasis

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Vasculotide reduces endothelial permeability and tumor cell extravasation in the absence of binding to or agonistic activation of Tie2

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Endogenous Sterol Metabolites Regulate Growth of EGFR/KRAS-Dependent Tumors via LXR

(2015) Linara Gabitova et al.   Cell Reports

Obesity and cancer—mechanisms underlying tumour progression and recurrence

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Proteomic Analysis of Two Metabolic Proteins with Potential to Translocate to Plasma Membrane Associated with Tumor Metastasis Development and Drug Targets

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27-Hydroxycholesterol Links Hypercholesterolemia and Breast Cancer Pathophysiology

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Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells

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Targeting C4-Demethylating Genes in the Cholesterol Pathway Sensitizes Cancer Cells to EGF Receptor Inhibitors via Increased EGF Receptor Degradation

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The Stimulation of HSD17B7 Expression by Estradiol Provides a Powerful Feed-Forward Mechanism for Estradiol Biosynthesis in Breast Cancer Cells

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Intratumoral Estrogen Disposition in Breast Cancer

(2010) B. P. Haynes et al.   CLINICAL CANCER RESEARCH

Localized and reversible TGFβ signalling switches breast cancer cells from cohesive to single cell motility

(2009) Silvia Giampieri et al.   NATURE CELL BIOLOGY

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