The anti-inflammatory and analgesic effects of intraperitoneal melatonin after spinal nerve ligation are mediated by inhibition of the NF-κB/NLRP3 inflammasome signaling pathway

Melatonin Effects on Glucose Metabolism: Time To Unlock the Controversy

(2020) Marta Garaulet et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Neuraxial Cytokines in Pain States

(2020) Gilson Gonçalves dos Santos et al.   Frontiers in Immunology

Bruton tyrosine kinase deficiency augments NLRP3 inflammasome activation and causes IL-1β–mediated colitis

(2020) Liming Mao et al.   JOURNAL OF CLINICAL INVESTIGATION

MicroRNA-1224 splicing circularRNA-Filip1l in an Ago2- dependent manner regulates chronic inflammatory pain via targeting Ubr5

(2019) Zhiqiang Pan et al.   JOURNAL OF NEUROSCIENCE

Inflammatory regulatory network mediated by the joint action of NF-kB, STAT3, and AP-1 factors is involved in many human cancers

(2019) Zhe Ji et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chondroprotective effects of platelet lysate towards monoiodoacetate-induced arthritis by suppression of TNF-α-induced activation of NF-ĸB pathway in chondrocytes

(2019) Li Yan et al.   Aging-US

A Novel Sex-Dependent Target for the Treatment of Postoperative Pain: The NLRP3 Inflammasome

(2019) Ashley M. Cowie et al.   Frontiers in Neurology

Neurosteroids and neuropathic pain management: Basic evidence and therapeutic perspectives

(2019) Laurence Meyer et al.   FRONTIERS IN NEUROENDOCRINOLOGY

Melatonin mediates mucosal immune cells, microbial metabolism, and rhythm crosstalk: A therapeutic target to reduce intestinal inflammation

(2019) Ning Ma et al.   MEDICINAL RESEARCH REVIEWS

Pharmacological inhibition of the NLRP3 inflammasome as a potential target for cancer-induced bone pain

(2019) Shu-Ping Chen et al.   PHARMACOLOGICAL RESEARCH

TNFR2 promotes Treg-mediated recovery from neuropathic pain across sexes

(2019) Roman Fischer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ginsenoside Rg1 attenuates cardiomyocyte apoptosis and inflammation via the TLR4/NF‐kB/NLRP3 pathway

(2019) Man Luo et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Melatonin Plus Folic Acid Treatment Ameliorates Reserpine-Induced Fibromyalgia: An Evaluation of Pain, Oxidative Stress, and Inflammation

(2019) Roberta Fusco et al.   Antioxidants

Inflammasome biology, molecular pathology and therapeutic implications

(2018) Fawaz Awad et al.   PHARMACOLOGY & THERAPEUTICS

8-O-Acetyl Shanzhiside Methylester From Lamiophlomis Rotata Reduces Neuropathic Pain by Inhibiting the ERK/TNF-α Pathway in Spinal Astrocytes

(2018) Wei Zhang et al.   Frontiers in Cellular Neuroscience

Crocin, a natural product attenuates lipopolysaccharide-induced anxiety and depressive-like behaviors through suppressing NF-kB and NLRP3 signaling pathway

(2018) Lang Zhang et al.   BRAIN RESEARCH BULLETIN

Inhibitors of NF-κB and P2X7/NLRP3/Caspase 1 pathway in microglia: Novel therapeutic opportunities in neuroinflammation induced early-stage Alzheimer’s disease

(2018) Baban S. Thawkar et al.   JOURNAL OF NEUROIMMUNOLOGY

The IASP classification of chronic pain for ICD-11

(2018) Joachim Scholz et al.   PAIN

Melatonin limits paclitaxel-induced mitochondrial dysfunction in vitro and protects against paclitaxel-induced neuropathic pain in the rat

(2017) Helen F. Galley et al.   JOURNAL OF PINEAL RESEARCH

Activation of NLRP3 inflammasome in peripheral nerve contributes to paclitaxel-induced neuropathic pain

(2017) Min Jia et al.   Molecular Pain

Upregulation of CX3CL1 mediated by NF-κB activation in dorsal root ganglion contributes to peripheral sensitization and chronic pain induced by oxaliplatin administration

(2017) Jing Wang et al.   Molecular Pain

Melatonin Suppresses Neuropathic Pain via MT2-Dependent and -Independent Pathways in Dorsal Root Ganglia Neurons of Mice

(2017) Jia-Ji Lin et al.   Theranostics

Bay11-7082 attenuates neuropathic pain via inhibition of nuclear factor-kappa B and nucleotide-binding domain-like receptor protein 3 inflammasome activation in dorsal root ganglions in a rat model of lumbar disc herniation

(2017) Ailiang Zhang et al.   Journal of Pain Research

Targeting Melatonin MT2 Receptors: A Novel Pharmacological Avenue for Inflammatory and Neuropathic Pain

(2017) Luca Posa et al.   CURRENT MEDICINAL CHEMISTRY

Assembly and regulation of ASC specks

(2016) Florian Hoss et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Atrial natriuretic peptide down-regulates LPS/ATP-mediated IL-1β release by inhibiting NF-kB, NLRP3 inflammasome and caspase-1 activation in THP-1 cells

(2015) Letizia Mezzasoma et al.   IMMUNOLOGIC RESEARCH

Analgesic, Anxiolytic and Anaesthetic Effects of Melatonin: New Potential Uses in Pediatrics

(2015) Lucia Marseglia et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Mutation in cytochrome b gene of mitochondrial DNA in a family with fibromyalgia is associated with NLRP3-inflammasome activation

(2015) Mario D Cordero et al.   JOURNAL OF MEDICAL GENETICS

In vivo and systems biology studies implicate IL-18 as a central mediator in chronic pain

(2015) Kiran Vasudeva et al.   JOURNAL OF NEUROIMMUNOLOGY

Melatonin decreases muscular oxidative stress and inflammation induced by strenuous exercise and stimulates growth factor synthesis

(2015) Leandro da Silva Borges et al.   JOURNAL OF PINEAL RESEARCH

Identification of IncRNA Expression Profile in the Spinal Cord of Mice following Spinal Nerve Ligation-Induced Neuropathic Pain

(2015) Bao-Chun Jiang et al.   Molecular Pain

Analgesic and antihyperalgesic effects of melatonin in a human inflammatory pain model

(2015) Lars P. H. Andersen et al.   PAIN

Selective melatonin MT2 receptor ligands relieve neuropathic pain through modulation of brainstem descending antinociceptive pathways

(2015) Martha Lopez-Canul et al.   PAIN

Melatonin and brain inflammaging

(2015) Rüdiger Hardeland et al.   PROGRESS IN NEUROBIOLOGY

RNA viruses promote activation of the NLRP3 inflammasome through a RIP1-RIP3-DRP1 signaling pathway

(2014) Xiaqiong Wang et al.   NATURE IMMUNOLOGY

Transmitting Pain and Itch Messages: A Contemporary View of the Spinal Cord Circuits that Generate Gate Control

(2014) João Braz et al.   NEURON

Modulating the delicate glial–neuronal interactions in neuropathic pain: Promises and potential caveats

(2014) Vinod Tiwari et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Melatonin in Antinociception: Its Therapeutic Applications

(2012) Venkatramanujam Srinivasan et al.   Current Neuropharmacology

Glia as a Link between Neuroinflammation and Neuropathic Pain

(2012) Mithilesh Kumar Jha et al.   Immune Network

Human NLRP3 inflammasome activation is Nox1-4 independent

(2010) R. van Bruggen et al.   BLOOD

The neuro-immune balance in neuropathic pain: Involvement of inflammatory immune cells, immune-like glial cells and cytokines

(2010) Paul J. Austin et al.   JOURNAL OF NEUROIMMUNOLOGY

Neuronal circuitry for pain processing in the dorsal horn

(2010) Andrew J. Todd   NATURE REVIEWS NEUROSCIENCE

Antinociceptive effects of melatonin in a rat model of post-inflammatory visceral hyperalgesia: A centrally mediated process

(2010) Aaron Mickle et al.   PAIN