Perampanel effects in the WAG/Rij rat model of epileptogenesis, absence epilepsy, and comorbid depressive-like behavior

Cognitive effects of adjunctive perampanel for partial-onset seizures: A randomized trial

(2016) Kimford J. Meador et al.   EPILEPSIA

Challenges in the clinical development of new antiepileptic drugs

(2016) Valentina Franco et al.   PHARMACOLOGICAL RESEARCH

Development and Validation of an HPLC-UV Assay for the Therapeutic Monitoring of the New Antiepileptic Drug Perampanel in Human Plasma

(2016) Valentina Franco et al.   THERAPEUTIC DRUG MONITORING

Differential role of AMPA receptors in mouse tests of antidepressant and anxiolytic action

(2015) Jesper T Andreasen et al.   BRAIN RESEARCH

Antiepileptogenic effects of the selective COX-2 inhibitor etoricoxib, on the development of spontaneous absence seizures in WAG/Rij rats

(2015) Rita Citraro et al.   BRAIN RESEARCH BULLETIN

Antidepressants but not antipsychotics have antiepileptogenic effects with limited effects on comorbid depressive-like behaviour in the WAG/Rij rat model of absence epilepsy

(2015) Rita Citraro et al.   BRITISH JOURNAL OF PHARMACOLOGY

Psychiatric and behavioral adverse events in randomized clinical studies of the noncompetitive AMPA receptor antagonist perampanel

(2015) Alan B. Ettinger et al.   EPILEPSIA

Analysis of pooled phase III trials of adjunctive perampanel for epilepsy: Impact of mechanism of action and pharmacokinetics on clinical outcomes

(2015) Patrick Kwan et al.   EPILEPSY RESEARCH

Oral exposure to low-dose of nonylphenol impairs memory performance in Sprague-Dawley rats

(2015) Shinichiro Kawaguchi et al.   JOURNAL OF TOXICOLOGICAL SCIENCES

Cognitive impairments and neuronal injury in different brain regions of a genetic rat model of absence epilepsy

(2015) M. Jafarian et al.   NEUROSCIENCE

Protective effects of some statins on epileptogenesis and depressive-like behavior in WAG/Rij rats, a genetic animal model of absence epilepsy

(2014) Rita Citraro et al.   EPILEPSIA

Targeting α-amino-3-hydroxyl-5-methyl-4-isoxazole-propionate receptors in epilepsy

(2014) Rita Citraro et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Past and Present Definitions of Epileptogenesis and Its Biomarkers

(2014) Asla Pitkänen et al.   Neurotherapeutics

Preclinical pharmacology of perampanel, a selective non-competitive AMPA receptor antagonist

(2013) M. A. Rogawski et al.   ACTA NEUROLOGICA SCANDINAVICA

AMPA Receptor antagonist NBQX attenuates later-life epileptic seizures and autistic-like social deficits following neonatal seizures

(2013) Jocelyn J. Lippman-Bell et al.   EPILEPSIA

Phosphorylation of AMPA-Type Glutamate Receptors: The Trigger of Epileptogenesis?

(2013) J. Bakker et al.   JOURNAL OF NEUROSCIENCE

Age-dependent decline in learning and memory performances of WAG/Rij rat model of absence epilepsy

(2012) Ayşe Karson et al.   Behavioral and Brain Functions

Rhythm and blues: Animal models of epilepsy and depression comorbidity

(2012) S. Alisha Epps et al.   BIOCHEMICAL PHARMACOLOGY

New AMPA antagonists in epilepsy

(2012) Emilio Russo et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Ameliorating effects of aripiprazole on cognitive functions and depressive-like behavior in a genetic rat model of absence epilepsy and mild-depression comorbidity

(2012) Emilio Russo et al.   NEUROPHARMACOLOGY

Perampanel: A novel, orally active, noncompetitive AMPA-receptor antagonist that reduces seizure activity in rodent models of epilepsy

(2011) Takahisa Hanada et al.   EPILEPSIA

Spike–wave discharges are necessary for the expression of behavioral depression-like symptoms

(2009) Karine Yu Sarkisova et al.   EPILEPSIA

Early treatment suppresses the development of spike-wave epilepsy in a rat model

(2008) Hal Blumenfeld et al.   EPILEPSIA

Enhancement of anti-absence effects of ethosuximide by low doses of a noncompetitive α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor antagonist in a genetic animal model of absence epilepsy

(2008) Emilio Russo et al.   EPILEPSY & BEHAVIOR

Early Alterations of AMPA Receptors Mediate Synaptic Potentiation Induced by Neonatal Seizures

(2008) S. N. Rakhade et al.   JOURNAL OF NEUROSCIENCE