Protective effects of some statins on epileptogenesis and depressive-like behavior in WAG/Rij rats, a genetic animal model of absence epilepsy

Protective effect of HMG CoA reductase inhibitors against running wheel activity induced fatigue, anxiety like behavior, oxidative stress and mitochondrial dysfunction in mice

(2014) Anil Kumar et al.   Pharmacological Reports

Effects of new antiepileptic drugs on circulatory markers for vascular risk in patients with newly diagnosed epilepsy

(2013) Dong Wook Kim et al.   EPILEPSIA

Lamotrigine positively affects the development of psychiatric comorbidity in epileptic animals, while psychiatric comorbidity aggravates seizures

(2013) Emilio Russo et al.   EPILEPSY & BEHAVIOR

The relationship between statins and depression: a review of the literature

(2013) Hong You et al.   EXPERT OPINION ON PHARMACOTHERAPY

Bi-lateral changes to hippocampal cholesterol levels during epileptogenesis and in chronic epilepsy following focal-onset status epilepticus in mice

(2012) Maura Heverin et al.   BRAIN RESEARCH

Chronic administration of atorvastatin induced anti-convulsant effects in mice: The role of nitric oxide

(2012) Leila Moezi et al.   EPILEPSY & BEHAVIOR

Acute atorvastatin treatment exerts antidepressant-like effect in mice via the l-arginine–nitric oxide–cyclic guanosine monophosphate pathway and increases BDNF levels

(2012) Fabiana K. Ludka et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Mechanisms and Clinical Evidence of the Pleiotropic Effects of the Hydroxy-Methyl-Glutaryl-CoA Reductase Inhibitors in Central Nervous System Disorders: A Comprehensive Review

(2012) Danielle Yanuck et al.   INTERNATIONAL JOURNAL OF NEUROSCIENCE

The involvement of nitric oxide in the anti-seizure effect of acute atorvastatin treatment in mice

(2012) Hamed Shafaroodi et al.   NEUROLOGICAL RESEARCH

mTOR inhibition modulates epileptogenesis, seizures and depressive behavior in a genetic rat model of absence epilepsy

(2012) Emilio Russo et al.   NEUROPHARMACOLOGY

Antiepileptic action of N-palmitoylethanolamine through CB1 and PPAR-α receptor activation in a genetic model of absence epilepsy

(2012) Rita Citraro et al.   NEUROPHARMACOLOGY

Ameliorating effects of aripiprazole on cognitive functions and depressive-like behavior in a genetic rat model of absence epilepsy and mild-depression comorbidity

(2012) Emilio Russo et al.   NEUROPHARMACOLOGY

The role of inflammation in epileptogenesis

(2012) Annamaria Vezzani et al.   NEUROPHARMACOLOGY

Cytokines and Absence Seizures in a Genetic Rat Model

(2012) G. van Luijtelaar et al.   NEUROPHYSIOLOGY

Protective activity of α-lactoalbumin (ALAC), a whey protein rich in tryptophan, in rodent models of epileptogenesis

(2012) E. Russo et al.   NEUROSCIENCE

Pharmacodynamic potentiation of antiepileptic drugs’ effects by some HMG-CoA reductase inhibitors against audiogenic seizures in DBA/2 mice

(2012) Emilio Russo et al.   PHARMACOLOGICAL RESEARCH

Vigabatrin has antiepileptogenic and antidepressant effects in an animal model of epilepsy and depression comorbidity

(2011) Emilio Russo et al.   BEHAVIOURAL BRAIN RESEARCH

Differential effects of atorvastatin treatment and withdrawal on pentylenetetrazol-induced seizures

(2011) Vinícius Rafael Funck et al.   EPILEPSIA

Atorvastatin treatment during epileptogenesis in a rat model for temporal lobe epilepsy

(2011) Erwin A. van Vliet et al.   EPILEPSIA

Effects of early long-term treatment with antiepileptic drugs on development of seizures and depressive-like behavior in a rat genetic absence epilepsy model

(2011) Emilio Russo et al.   EPILEPSIA

Molecular cascades that mediate the influence of inflammation on epilepsy

(2011) Alon Friedman et al.   EPILEPSIA

Mechanisms of epileptogenesis and potential treatment targets

(2011) Asla Pitkänen et al.   LANCET NEUROLOGY

IL-1β is induced in reactive astrocytes in the somatosensory cortex of rats with genetic absence epilepsy at the onset of spike-and-wave discharges, and contributes to their occurrence

(2011) Demet Akin et al.   NEUROBIOLOGY OF DISEASE

Administration of Simvastatin after Kainic Acid-Induced Status Epilepticus Restrains Chronic Temporal Lobe Epilepsy

(2011) Chuncheng Xie et al.   PLoS One

Statins in Neurological Disorders: Mechanisms and Therapeutic Value

(2011) Allison B. Reiss et al.   TheScientificWorldJOURNAL

Lovastatin decreases the synthesis of inflammatory mediators in the hippocampus and blocks the hyperthermia of rats submitted to long-lasting status epilepticus

(2010) Telma Luciana Furtado Gouveia et al.   EPILEPSY & BEHAVIOR

The Use of Statins After a Cardiac Intervention Is Associated With Reduced Risk of Subsequent Depression

(2010) Lesley Stafford et al.   JOURNAL OF CLINICAL PSYCHIATRY

Changes in Brain Cholesterol Metabolome After Excitotoxicity

(2010) Wei-Yi Ong et al.   MOLECULAR NEUROBIOLOGY

Animal models of neuropsychiatric disorders

(2010) Eric J Nestler et al.   NATURE NEUROSCIENCE

Statin use and risk of epilepsy: A nested case-control study

(2010) M. Etminan et al.   NEUROLOGY

The WAG/Rij strain: A genetic animal model of absence epilepsy with comorbidity of depressiony

(2010) Karine Sarkisova et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Comparison of the antiepileptogenic effects of an early long-term treatment with ethosuximide or levetiracetam in a genetic animal model of absence epilepsy

(2009) Emilio Russo et al.   EPILEPSIA

Statin inhibits kainic acid-induced seizure and associated inflammation and hippocampal cell death

(2008) Jin-Koo Lee et al.   NEUROSCIENCE LETTERS