Enhancing the chemosensitivity of HepG2 cells towards cisplatin by organoselenium pseudopeptides

Anticancer activity of new cationic arylthiophenes against hepatocellular carcinoma

(2021) Sara A. Al-Shun et al.   LIFE SCIENCES

Synthetic peroxides promote apoptosis of cancer cells inhibiting of P‐glycoprotein ABCB5

(2020) Ivan A. Yaremenko et al.   ChemMedChem

Knockdown of THOC1 reduces the proliferation of hepatocellular carcinoma and increases the sensitivity to cisplatin

(2020) Shijiao Cai et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Molecular Bases of Drug Resistance in Hepatocellular Carcinoma

(2020) Jose J.G. Marin et al.   Cancers

Dihydroartemisinin‐bile acid hybridization as an effective approach to enhance dihydroartemisinin anticancer activity

(2019) maria luisa navacchia et al.   ChemMedChem

Cisplatin: The first metal based anticancer drug

(2019) Sumit Ghosh   BIOORGANIC CHEMISTRY

Obesity and liver cancer

(2019) Carlo Saitta et al.   Annals of Hepatology

New Insights into Mechanisms of Cisplatin Resistance: From Tumor Cell to Microenvironment

(2019) Shang-Hung Chen et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Oridonin elevates sensitivity of ovarian carcinoma cells to cisplatin via suppressing cisplatin-mediated autophagy

(2019) Yaxian Zhao et al.   LIFE SCIENCES

Synthesis and biochemical studies of novel organic selenides with increased selectivity for hepatocellular carcinoma and breast adenocarcinoma

(2019) Saad Shaaban et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Cytoprotective and antioxidant properties of organic selenides for the myelin-forming cells, oligodendrocytes

(2018) Saad Shaaban et al.   BIOORGANIC CHEMISTRY

Novel Peroxides as Promising Anticancer Agents with Unexpected Depressed Antimalarial Activity

(2018) Paolo Coghi et al.   ChemMedChem

Selenides and Diselenides: A Review of Their Anticancer and Chemopreventive Activity

(2018) Mónica Álvarez-Pérez et al.   MOLECULES

The trends in incidence of primary liver cancer caused by specific etiologies: Results from the Global Burden of Disease Study 2016 and implications for liver cancer prevention

(2018) Zhenqiu Liu et al.   JOURNAL OF HEPATOLOGY

A comprehensive complex systems approach to the study and analysis of mammalian cell cycle control system in the presence of DNA damage stress

(2017) Ali Abroudi et al.   JOURNAL OF THEORETICAL BIOLOGY

Expeditious Entry to Functionalized Pseudo-peptidic Organoselenide Redox Modulators via Sequential Ugi/SN Methodology

(2016) Saad Shaaban et al.   Anti-Cancer Agents in Medicinal Chemistry

Combinatorial synthesis, in silico , molecular and biochemical studies of tetrazole-derived organic selenides with increased selectivity against hepatocellular carcinoma

(2016) Saad Shaaban et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Cisplatin resistance and opportunities for precision medicine

(2016) Lauren Amable   PHARMACOLOGICAL RESEARCH

Molecular Mechanism Behind the Synergistic Activity of Diphenylmethyl Selenocyanate and Cisplatin Against Murine Tumor Model

(2015) Pramita Chakraborty et al.   Anti-Cancer Agents in Medicinal Chemistry

Organoselenocyanates and symmetrical diselenides redox modulators: Design, synthesis and biological evaluation

(2015) Saad Shaaban et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Groebke–Blackburn–Bienaymé multicomponent reaction: emerging chemistry for drug discovery

(2015) Saad Shaaban et al.   MOLECULAR DIVERSITY

Approach for chemosensitization of cisplatin-resistant ovarian cancer by cucurbitacin B

(2015) Fardous F. El-Senduny et al.   TUMOR BIOLOGY

Mechanism of Cisplatin-Induced Cytotoxicity Is Correlated to Impaired Metabolism Due to Mitochondrial ROS Generation

(2015) Yong-Min Choi et al.   PLoS One

Diversity-oriented synthesis of dihydrobenzoxazepinones by coupling the Ugi multicomponent reaction with a Mitsunobu cyclization

(2014) Lisa Moni et al.   Beilstein Journal of Organic Chemistry

2-[5-Selenocyanato-pentyl]-6-amino-benzo[de]isoquinoline-1,3-dione inhibits angiogenesis, induces p53 dependent mitochondrial apoptosis and enhances therapeutic efficacy of cyclophosphamide

(2014) Somnath Singha Roy et al.   BIOCHIMIE

Sulfur, selenium and tellurium pseudopeptides: Synthesis and biological evaluation

(2014) Saad Shaaban et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Fused heterocyclic compounds bearing bridgehead nitrogen as potent HIV-1 NNRTIs. Part 1: Design, synthesis and biological evaluation of novel 5,7-disubstituted pyrazolo[1,5-a]pyrimidine derivatives

(2014) Ye Tian et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Small Heterocycles in Multicomponent Reactions

(2014) Benjamin H. Rotstein et al.   CHEMICAL REVIEWS

Thiazolothiadiazoles and Thiazolooxadiazoles: Synthesis and Biological Applications

(2014) Bakr Abdel-Wahab et al.   SYNTHESIS-STUTTGART

The early research and development of ebselen

(2013) Michael J. Parnham et al.   BIOCHEMICAL PHARMACOLOGY

Diversity-Oriented Synthesis Yields a New Drug Lead for Treatment of Chagas Disease

(2013) Sivaraman Dandapani et al.   ACS Medicinal Chemistry Letters

Novel peptidomimetic compounds containing redox active chalcogens and quinones as potential anticancer agents

(2012) Saad Shaaban et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Hits, leads and drugs against malaria through diversity-oriented synthesis

(2012) Sivaraman Dandapani et al.   Future Medicinal Chemistry

Groebke multicomponent reaction and subsequent nucleophilic aromatic substitution for a convenient synthesis of 3,8-diaminoimidazo[1,2-a]pyrazines as potential kinase inhibitors

(2011) Margherita Guasconi et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Drug Combination Studies and Their Synergy Quantification Using the Chou-Talalay Method

(2010) T.-C. Chou   CANCER RESEARCH

Synthesis and Selective Anticancer Activity of Organochalcogen Based Redox Catalysts

(2010) Mandy Doering et al.   JOURNAL OF MEDICINAL CHEMISTRY

Towards molecular diversity: dealkylation of tert-butyl amine in Ugi-type multicomponent reaction product establishes tert-butyl isocyanide as a useful convertible isonitrile

(2010) Sankar K. Guchhait et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Curcumin induces chemo/radio-sensitization in ovarian cancer cells and curcumin nanoparticles inhibit ovarian cancer cell growth

(2010) Murali M Yallapu et al.   Journal of Ovarian Research

Multicomponent reactions for the synthesis of multifunctional agents with activity against cancer cells

(2009) Saad Shabaan et al.   CHEMICAL COMMUNICATIONS

Efficient Synthesis Of Arrays Of Amino Acid Derived Ugi Products With Subsequent Amidation

(2009) Wei Wang et al.   JOURNAL OF COMBINATORIAL CHEMISTRY

Organoselenium Compounds in Cancer Chemoprevention

(2008) Rajesh Naithani   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Beyond the Ugi reaction: less conventional interactions between isocyanides and iminium species

(2008) Laurent El Kaim et al.   TETRAHEDRON