4.7 Article

Multicomponent reactions for the synthesis of multifunctional agents with activity against cancer cells

Journal

CHEMICAL COMMUNICATIONS
Volume -, Issue 31, Pages 4702-4704

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/b823149d

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Funding

  1. University of Saarland, Ministry of Economics and Science of Saarland
  2. Deutsche Forschungsgemeinschaft [JA1741/2-1]
  3. European Union [215009]
  4. National Cancer Institute
  5. government of Egypt

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Multicomponent Passerini and Ugi reactions enable the fast and efficient synthesis of redox-active multifunctional selenium and tellurium compounds, of which some show considerable cytotoxicity against specific cancer cells.

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