A constriction channel analysis of astrocytoma stiffness and disease progression

Cell adhesion in cancer: Beyond the migration of single cells

(2020) Michalina Janiszewska et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Insulin Enhances Migration and Invasion in Prostate Cancer Cells by Up-Regulation of FOXC2

(2019) Phoebe L. Sarkar et al.   Frontiers in Endocrinology

Differential Contributions of Actin and Myosin to the Physical Phenotypes and Invasion of Pancreatic Cancer Cells

(2019) Angelyn V. Nguyen et al.   Cellular and Molecular Bioengineering

Mechanisms of 3D cell migration

(2019) Kenneth M. Yamada et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Cell Adhesiveness Serves as a Biophysical Marker for Metastatic Potential

(2019) Pranjali Beri et al.   CANCER RESEARCH

Aggressive prostate cancer cell nuclei have reduced stiffness

(2018) Zeina S. Khan et al.   Biomicrofluidics

Characterization of the mechanical properties of cancer cells in 3D matrices in response to collagen concentration and cytoskeletal inhibitors

(2018) Jessica E. Kim et al.   Integrative Biology

Predicting cancer cell invasion by single-cell physical phenotyping

(2018) Kendra D. Nyberg et al.   Integrative Biology

Multiparameter cell-tracking intrinsic cytometry for single-cell characterization

(2018) N. Apichitsopa et al.   LAB ON A CHIP

Kernel-Based Microfluidic Constriction Assay for Tumor Sample Identification

(2018) Xiang Ren et al.   ACS Sensors

Mechanical and Systems Biology of Cancer

(2018) Fabian Spill et al.   Computational and Structural Biotechnology Journal

A numerical model suggests the interplay between nuclear plasticity and stiffness during a perfusion assay

(2017) Solenne Deveraux et al.   JOURNAL OF THEORETICAL BIOLOGY

A combined experimental and theoretical approach towards mechanophenotyping of biological cells using a constricted microchannel

(2017) A. Raj et al.   LAB ON A CHIP

Biophysical isolation and identification of circulating tumor cells

(2017) James Che et al.   LAB ON A CHIP

Mechanical characterization of cancer cells during TGF-β1-induced epithelial-mesenchymal transition using an electrodeformation-based microchip

(2017) Yao Teng et al.   SENSORS AND ACTUATORS B-CHEMICAL

Single-Cell Mechanical Characteristics Analyzed by Multiconstriction Microfluidic Channels

(2017) Xiang Ren et al.   ACS Sensors

High-throughput physical phenotyping of cell differentiation

(2017) Jonathan Lin et al.   Microsystems & Nanoengineering

The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary

(2016) David N. Louis et al.   ACTA NEUROPATHOLOGICA

A Chemomechanical Model for Nuclear Morphology and Stresses during Cell Transendothelial Migration

(2016) Xuan Cao et al.   BIOPHYSICAL JOURNAL

Stiffness of pancreatic cancer cells is associated with increased invasive potential

(2016) Angelyn V. Nguyen et al.   Integrative Biology

Cancer cells become less deformable and more invasive with activation of β-adrenergic signaling

(2016) Tae-Hyung Kim et al.   JOURNAL OF CELL SCIENCE

Cell elasticity with altered cytoskeletal architectures across multiple cell types

(2016) Martha E. Grady et al.   Journal of the Mechanical Behavior of Biomedical Materials

The physical origins of transit time measurements for rapid, single cell mechanotyping

(2016) Kendra D. Nyberg et al.   LAB ON A CHIP

Astrocytes in Migration

(2016) Jiang Shan Zhan et al.   NEUROCHEMICAL RESEARCH

Mapping intracellular mechanics on micropatterned substrates

(2016) Kalpana Mandal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Modelling of an uniaxial single-sided magnetically actuated cell-stretching device

(2016) Harshad Kamble et al.   SENSORS AND ACTUATORS A-PHYSICAL

Interplay of active processes modulates tension and drives phase transition in self-renewing, motor-driven cytoskeletal networks

(2016) Michael Mak et al.   Nature Communications

Extracting Cell Stiffness from Real-Time Deformability Cytometry: Theory and Experiment

(2015) Alexander Mietke et al.   BIOPHYSICAL JOURNAL

Microconstriction Arrays for High-Throughput Quantitative Measurements of Cell Mechanical Properties

(2015) Janina R. Lange et al.   BIOPHYSICAL JOURNAL

Mechanisms regulating glioma invasion

(2015) Ivy Paw et al.   CANCER LETTERS

High-throughput linear optical stretcher for mechanical characterization of blood cells

(2015) Kevin B. Roth et al.   CYTOMETRY PART A

Lamins at the crossroads of mechanosignaling

(2015) Selma Osmanagic-Myers et al.   GENES & DEVELOPMENT

An optofluidic constriction chip for monitoring metastatic potential and drug response of cancer cells

(2015) R. Martinez Vazquez et al.   Integrative Biology

Multiscale mechanobiology: computational models for integrating molecules to multicellular systems

(2015) Michael Mak et al.   Integrative Biology

β-PIX controls intracellular viscoelasticity to regulate lung cancer cell migration

(2015) Helen Wenshin Yu et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Real-time deformability cytometry: on-the-fly cell mechanical phenotyping

(2015) Oliver Otto et al.   NATURE METHODS

Survival and low-grade glioma: the emergence of genetic information

(2015) Elizabeth B. Claus et al.   Neurosurgical Focus

Local mechanical properties of bladder cancer cells measured by AFM as a signature of metastatic potential

(2015) Y. Abidine et al.   European Physical Journal Plus

FACS-style detection for real-time cell viscoelastic cytometry

(2015) A. Kasukurti et al.   RSC Advances

Constriction Channel Based Single-Cell Mechanical Property Characterization

(2015) Chengcheng Xue et al.   Micromachines

Insulin Promotes Proliferation and Migration of Breast Cancer Cells through the Extracellular Regulated Kinase Pathway

(2014) Feng Pan et al.   Asian Pacific Journal of Cancer Prevention

Insulin regulates monocyte trans-endothelial migration through surface expression of macrophage-1 antigen

(2014) Seo Yeon Jin et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Probing the Stochastic, Motor-Driven Properties of the Cytoplasm Using Force Spectrum Microscopy

(2014) Ming Guo et al.   CELL

Nuclear Deformability Constitutes a Rate-Limiting Step During Cell Migration in 3-D Environments

(2014) Patricia M. Davidson et al.   Cellular and Molecular Bioengineering

Atomic force microscope-based single cell force spectroscopy of breast cancer cell lines: An approach for evaluating cellular invasion

(2014) Ramin Omidvar et al.   JOURNAL OF BIOMECHANICS

Nuclear lamin stiffness is a barrier to 3D migration, but softness can limit survival

(2014) Takamasa Harada et al.   JOURNAL OF CELL BIOLOGY

A neurocentric perspective on glioma invasion

(2014) Vishnu Anand Cuddapah et al.   NATURE REVIEWS NEUROSCIENCE

Compression stiffening of brain and its effect on mechanosensing by glioma cells

(2014) Katarzyna Pogoda et al.   NEW JOURNAL OF PHYSICS

Oncogenes induce a vimentin filament collapse mediated by HDAC6 that is linked to cell stiffness

(2014) L.-S. Z. Rathje et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A constriction channel based microfluidic system enabling continuous characterization of cellular instantaneous Young's modulus

(2014) Y.N. Luo et al.   SENSORS AND ACTUATORS B-CHEMICAL

A Microfluidic Technique to Probe Cell Deformability

(2014) David J. Hoelzle et al.   Jove-Journal of Visualized Experiments

Probing the mechanical properties of brain cancer cells using a microfluidic cell squeezer device

(2013) Z. S. Khan et al.   Biomicrofluidics

Viscoelasticity as a Biomarker for High-Throughput Flow Cytometry

(2013) Tobias Sawetzki et al.   BIOPHYSICAL JOURNAL

A serial micropipette microfluidic device with applications to cancer cell repeated deformation studies

(2013) Michael Mak et al.   Integrative Biology

Glioblastoma and Other Malignant Gliomas

(2013) Antonio Omuro   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Nuclear Envelope Composition Determines the Ability of Neutrophil-type Cells to Passage through Micron-scale Constrictions

(2013) Amy C. Rowat et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanical properties of cancer cytoskeleton depend on actin filaments to microtubules content: Investigating different grades of colon cancer cell lines

(2013) M. Pachenari et al.   JOURNAL OF BIOMECHANICS

Physical limits of cell migration: Control by ECM space and nuclear deformation and tuning by proteolysis and traction force

(2013) Katarina Wolf et al.   JOURNAL OF CELL BIOLOGY

Pinched-flow hydrodynamic stretching of single-cells

(2013) Jaideep S. Dudani et al.   LAB ON A CHIP

Characterizing deformability and surface friction of cancer cells

(2013) S. Byun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Microfluidic cytometer based on dual photodiode detection for cell size and deformability analysis

(2013) Qin-Qin Ji et al.   TALANTA

A physical sciences network characterization of non-tumorigenic and metastatic cells

(2013)   Scientific Reports

Microfluidics-Based Assessment of Cell Deformability

(2012) Andrea Adamo et al.   ANALYTICAL CHEMISTRY

AFM nano-mechanics and calcium dynamics of prostate cancer cells with distinct metastatic potential

(2012) Lyndon Bastatas et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Intracellular Mechanics and Activity of Breast Cancer Cells Correlate with Metastatic Potential

(2012) Naama Gal et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

A Finite Element Study of Micropipette Aspiration of Single Cells: Effect of Compressibility

(2012) Amirhossein Jafari Bidhendi et al.   Computational and Mathematical Methods in Medicine

Optical trapping microrheology in cultured human cells

(2012) E. Bertseva et al.   EUROPEAN PHYSICAL JOURNAL E

Elucidating mechanical transition effects of invading cancer cells with a subnucleus-scaled microfluidic serial dimensional modulation device

(2012) Michael Mak et al.   LAB ON A CHIP

Microfluidic system for cell mechanics analysis through dielectrophoresis

(2012) Isabella Guido et al.   MICROELECTRONIC ENGINEERING

Comparison of mechanical properties of normal and malignant thyroid cells

(2012) Meenakshi Prabhune et al.   MICRON

Cell Stiffness Is a Biomarker of the Metastatic Potential of Ovarian Cancer Cells

(2012) Wenwei Xu et al.   PLoS One

Hydrodynamic stretching of single cells for large population mechanical phenotyping

(2012) D. R. Gossett et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The ANN application in FEM modeling of mechanical properties of Al–Si alloy

(2011) Mohsen Ostad Shabani et al.   APPLIED MATHEMATICAL MODELLING

Cell Shape and Substrate Rigidity Both Regulate Cell Stiffness

(2011) Shang-You Tee et al.   BIOPHYSICAL JOURNAL

Mechanical Stiffness Grades Metastatic Potential in Patient Tumor Cells and in Cancer Cell Lines

(2011) V. Swaminathan et al.   CANCER RESEARCH

Hydrodynamic Cellular Volume Changes Enable Glioma Cell Invasion

(2011) S. Watkins et al.   JOURNAL OF NEUROSCIENCE

Classification of cell types using a microfluidic device for mechanical and electrical measurement on single cells

(2011) Jian Chen et al.   LAB ON A CHIP

The effects of cancer progression on the viscoelasticity of ovarian cell cytoskeleton structures

(2011) Alperen N. Ketene et al.   Nanomedicine-Nanotechnology Biology and Medicine

Extra-Neural Metastases of Malignant Gliomas: Myth or Reality?

(2011) Patrick Beauchesne   Cancers

Modeling cell entry into a micro-channel

(2010) Fong Yew Leong et al.   Biomechanics and Modeling in Mechanobiology

Nuclear mechanics during cell migration

(2010) Peter Friedl et al.   CURRENT OPINION IN CELL BIOLOGY

Cell deformation cytometry using diode-bar optical stretchers

(2010) Ihab Sraj et al.   JOURNAL OF BIOMEDICAL OPTICS

Mechanical properties of mammalian cells in suspension measured by electro-deformation

(2010) Luke A MacQueen et al.   JOURNAL OF MICROMECHANICS AND MICROENGINEERING

Astrocytes: biology and pathology

(2009) Michael V. Sofroniew et al.   ACTA NEUROPATHOLOGICA

Influence of Lamin A on the Mechanical Properties of Amphibian Oocyte Nuclei Measured by Atomic Force Microscopy

(2009) Jens Schäpe et al.   BIOPHYSICAL JOURNAL

Mechanics, malignancy, and metastasis: The force journey of a tumor cell

(2009) Sanjay Kumar et al.   CANCER AND METASTASIS REVIEWS

Oral Cancer Diagnosis by Mechanical Phenotyping

(2009) T. W. Remmerbach et al.   CANCER RESEARCH

Intracellular particle tracking as a tool for tumor cell characterization

(2009) Yixuan Li et al.   JOURNAL OF BIOMEDICAL OPTICS

Measurement of elastic properties of prostate cancer cells using AFM

(2008) Elsa Correia Faria et al.   ANALYST

Towards an integrated understanding of the structure and mechanics of the cell nucleus

(2008) Amy C. Rowat et al.   BIOESSAYS

Deformability study of breast cancer cells using microfluidics

(2008) H. W. Hou et al.   BIOMEDICAL MICRODEVICES

Analyzing cell mechanics in hematologic diseases with microfluidic biophysical flow cytometry

(2008) Michael J. Rosenbluth et al.   LAB ON A CHIP

Artificial neural network approach to predict the mechanical properties of Cu–Sn–Pb–Zn–Ni cast alloys

(2008) Mehmet Sirac Ozerdem et al.   MATERIALS & DESIGN

The Role of Myosin II in Glioma Invasion of the Brain

(2008) Christopher Beadle et al.   MOLECULAR BIOLOGY OF THE CELL

Management of Intracranial Hypertension

(2008) Leonardo Rangel-Castillo et al.   NEUROLOGIC CLINICS

Malignant Gliomas in Adults

(2008) Patrick Y. Wen et al.   NEW ENGLAND JOURNAL OF MEDICINE

A Neural Network Model for Cell Classification Based on Single-Cell Biomechanical Properties

(2008) Eric M. Darling et al.   TISSUE ENGINEERING PART A