WONOEP appraisal: Imaging biomarkers in epilepsy

Glutamate-Mediated Blood-Brain Barrier Opening: Implications for Neuroprotection and Drug Delivery

(2016) U. Vazana et al.   JOURNAL OF NEUROSCIENCE

Serial Quantitative TSPO-Targeted PET Reveals Peak Microglial Activation up to 2 Weeks After an Epileptogenic Brain Insult

(2016) M. Brackhan et al.   JOURNAL OF NUCLEAR MEDICINE

Metabolic Correlates of the Ictal-Interictal Continuum: FDG-PET During Continuous EEG

(2016) Aaron F. Struck et al.   Neurocritical Care

Clinical Applications of Simultaneous PET/MR Imaging Using (R)-[11C]-Verapamil with Cyclosporin A: Preliminary Results on a Surrogate Marker of Drug-Resistant Epilepsy

(2015) J.-W. Shin et al.   AMERICAN JOURNAL OF NEURORADIOLOGY

White matter abnormalities differentiate severe from benign temporal lobe epilepsy

(2015) Angelo Labate et al.   EPILEPSIA

Blood-brain barrier leakage after status epilepticus in rapamycin-treated rats I: Magnetic resonance imaging

(2015) Erwin A. van Vliet et al.   EPILEPSIA

Blood-brain barrier leakage after status epilepticus in rapamycin-treated rats II: Potential mechanisms

(2015) Erwin A. van Vliet et al.   EPILEPSIA

Bringing memory fMRI to the clinic: Comparison of seven memory fMRI protocols in temporal lobe epilepsy

(2015) Karren Towgood et al.   HUMAN BRAIN MAPPING

In Vivo PET Imaging Demonstrates Diminished Microglial Activation After Fingolimod Treatment in an Animal Model of Multiple Sclerosis

(2015) L. Airas et al.   JOURNAL OF NUCLEAR MEDICINE

Factors Governing P-Glycoprotein-Mediated Drug–Drug Interactions at the Blood–Brain Barrier Measured with Positron Emission Tomography

(2015) Thomas Wanek et al.   MOLECULAR PHARMACEUTICS

Brain inflammation in a chronic epilepsy model: Evolving pattern of the translocator protein during epileptogenesis

(2015) Halima Amhaoul et al.   NEUROBIOLOGY OF DISEASE

Memory fMRI predicts verbal memory decline after anterior temporal lobe resection

(2015) M. K. Sidhu et al.   NEUROLOGY

Analyzing the blood–brain barrier: The benefits of medical imaging in research and clinical practice

(2015) Yoash Chassidim et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Blood–brain barrier dysfunction, seizures and epilepsy

(2015) E.A. van Vliet et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Neuroinflammation in Temporal Lobe Epilepsy Measured Using Positron Emission Tomographic Imaging of Translocator Protein

(2015) Leah D. Gershen et al.   JAMA Neurology

Co-localization between the BOLD response and epileptiform discharges recorded by simultaneous intracranial EEG-fMRI at 3 T

(2015) Yahya Aghakhani et al.   NeuroImage-Clinical

Distributions of Irritative Zones Are Related to Individual Alterations of Resting-State Networks in Focal Epilepsy

(2015) Yinchen Song et al.   PLoS One

Synthesis and Evaluation of Translocator 18 kDa Protein (TSPO) Positron Emission Tomography (PET) Radioligands with Low Binding Sensitivity to Human Single Nucleotide Polymorphism rs6971

(2014) Paolo Zanotti-Fregonara et al.   ACS Chemical Neuroscience

Blood–Brain Barrier Imaging in Human Neuropathologies

(2014) Ronel Veksler et al.   ARCHIVES OF MEDICAL RESEARCH

Working memory network plasticity after anterior temporal lobe resection: a longitudinal functional magnetic resonance imaging study

(2014) Jason Stretton et al.   BRAIN

Neuroimaging of drug resistance in epilepsy

(2014) Matthias J. Koepp   CURRENT OPINION IN NEUROLOGY

From the Editors:Epilepsia'ssurvey on the necessity of the Wada test and intracranial electrodes for cortical mapping

(2014) Gary W. Mathern et al.   EPILEPSIA

A Novel, Noninvasive, Predictive Epilepsy Biomarker with Clinical Potential

(2014) M. Choy et al.   JOURNAL OF NEUROSCIENCE

Increased Permeability-Glycoprotein Inhibition at the Human Blood-Brain Barrier Can Be Safely Achieved by Performing PET During Peak Plasma Concentrations of Tariquidar

(2014) W. C. Kreisl et al.   JOURNAL OF NUCLEAR MEDICINE

(R)-[11C]PK11195 brain uptake as a biomarker of inflammation and antiepileptic drug resistance: Evaluation in a rat epilepsy model

(2014) Renée Marie Bogdanović et al.   NEUROPHARMACOLOGY

Imaging brain inflammation in epilepsy

(2014) H. Amhaoul et al.   NEUROSCIENCE

Past and Present Definitions of Epileptogenesis and Its Biomarkers

(2014) Asla Pitkänen et al.   Neurotherapeutics

Clinical Proton MR Spectroscopy in Central Nervous System Disorders

(2014) Gülin Öz et al.   RADIOLOGY

Characterization of atypical language activation patterns in focal epilepsy

(2013) Madison M. Berl et al.   ANNALS OF NEUROLOGY

Diffusion tensor imaging of hippocampal network plasticity

(2013) Alejandra Sierra et al.   Brain Structure & Function

Electroencephalography/functional magnetic resonance imaging responses help predict surgical outcome in focal epilepsy

(2013) Dongmei An et al.   EPILEPSIA

Epilepsy biomarkers

(2013) Jerome Engel et al.   EPILEPSIA

Can structural or functional changes following traumatic brain injury in the rat predict epileptic outcome?

(2013) Sandy R. Shultz et al.   EPILEPSIA

Radioligands targeting P-glycoprotein and other drug efflux proteins at the blood-brain barrier

(2013) Thomas Wanek et al.   JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS

MRI Biomarkers for Post-Traumatic Epileptogenesis

(2013) Riikka Immonen et al.   JOURNAL OF NEUROTRAUMA

P-glycoprotein expression and function in patients with temporal lobe epilepsy: a case-control study

(2013) Maria Feldmann et al.   LANCET NEUROLOGY

Longitudinal assessment of blood–brain barrier leakage during epileptogenesis in rats. A quantitative MRI study

(2013) E.A. van Vliet et al.   NEUROBIOLOGY OF DISEASE

[11C]quinidine and [11C]laniquidar PET imaging in a chronic rodent epilepsy model: Impact of epilepsy and drug-responsiveness

(2013) Stina Syvänen et al.   NUCLEAR MEDICINE AND BIOLOGY

(R)-[11C]verapamil is selectively transported by murine and human P-glycoprotein at the blood–brain barrier, and not by MRP1 and BCRP

(2013) Kerstin Römermann et al.   NUCLEAR MEDICINE AND BIOLOGY

Preoperative language lateralization in temporal lobe epilepsy (TLE) predicts peri-ictal, pre- and post-operative language performance: An fMRI study

(2013) C. Rosazza et al.   NeuroImage-Clinical

Disrupted segregation of working memory networks in temporal lobe epilepsy

(2013) J. Stretton et al.   NeuroImage-Clinical

PET imaging of brain inflammation during early epileptogenesis in a rat model of temporal lobe epilepsy

(2013) Stefanie Dedeurwaerdere et al.   EJNMMI Research

Advances in PET Imaging of P-Glycoprotein Function at the Blood-Brain Barrier

(2012) Stina Syvänen et al.   ACS Chemical Neuroscience

Mapping preictal and ictal haemodynamic networks using video-electroencephalography and functional imaging

(2012) Umair J. Chaudhary et al.   BRAIN

Blood-brain barrier dysfunction and epilepsy: Pathophysiologic role and therapeutic approaches

(2012) Nicola Marchi et al.   EPILEPSIA

In vivo imaging of glia activation using1H-magnetic resonance spectroscopy to detect putative biomarkers of tissue epileptogenicity

(2012) Marta Filibian et al.   EPILEPSIA

Intracranial EEG-fMRI analysis of focal epileptiform discharges in humans

(2012) Cameron B. J. Cunningham et al.   EPILEPSIA

Who needs a Wada test? Present clinical indications for amobarbital procedures

(2012) Kathrin Wagner et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Increased In Vivo Expression of an Inflammatory Marker in Temporal Lobe Epilepsy

(2012) J. Hirvonen et al.   JOURNAL OF NUCLEAR MEDICINE

Detection of calcifications in vivo and ex vivo after brain injury in rat using SWIFT

(2012) Lauri Juhani Lehto et al.   NEUROIMAGE

Contribution of EEG/fMRI to the definition of the epileptic focus

(2012) F. Pittau et al.   NEUROLOGY

Brain inflammation as a biomarker in epilepsy

(2011) Annamaria Vezzani et al.   Biomarkers in Medicine

Abnormalities of lexical and semantic processing in left temporal lobe epilepsy: An fMRI study

(2011) Elizabeth J. Jensen et al.   EPILEPSIA

Transport of Selected PET Radiotracers by Human P-Glycoprotein (ABCB1) and Breast Cancer Resistance Protein (ABCG2): An In Vitro Screening

(2011) N. Tournier et al.   JOURNAL OF NUCLEAR MEDICINE

The neurochemical profile quantified by in vivo 1H NMR spectroscopy

(2011) João M.N. Duarte et al.   NEUROIMAGE

Imaging memory in temporal lobe epilepsy: predicting the effects of temporal lobe resection

(2010) S. B. Bonelli et al.   BRAIN

Imaging of P-glycoprotein-mediated pharmacoresistance in the hippocampus: Proof-of-concept in a chronic rat model of temporal lobe epilepsy

(2010) Hero Bartmann et al.   EPILEPSIA

EEG correlated functional MRI and postoperative outcome in focal epilepsy

(2010) R. Thornton et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

P-Glycoprotein Function at the Blood-Brain Barrier in Humans Can Be Quantified with the Substrate Radiotracer 11C-N-Desmethyl-Loperamide

(2010) W. C. Kreisl et al.   JOURNAL OF NUCLEAR MEDICINE

Reduced PBR/TSPO Expression After Minocycline Treatment in a Rat Model of Focal Cerebral Ischemia: A PET Study Using [18F]DPA-714

(2010) Abraham Martín et al.   MOLECULAR IMAGING AND BIOLOGY

The role of inflammation in epilepsy

(2010) Annamaria Vezzani et al.   Nature Reviews Neurology

fMRI assessment of language lateralization: An objective approach

(2010) David F. Abbott et al.   NEUROIMAGE

Simultaneous intracranial EEG and fMRI of interictal epileptic discharges in humans

(2010) Serge Vulliemoz et al.   NEUROIMAGE

Elevated cerebral blood flow and vascular density in the amygdala after status epilepticus in rats

(2010) Nick M.E.A Hayward et al.   NEUROSCIENCE LETTERS

Interictal arterial spin-labeling MRI perfusion in intractable epilepsy

(2009) N. Pendse et al.   JOURNAL OF NEURORADIOLOGY

Structure and function of the blood–brain barrier

(2009) N. Joan Abbott et al.   NEUROBIOLOGY OF DISEASE

Independent component analysis reveals dynamic ictal BOLD responses in EEG-fMRI data from focal epilepsy patients

(2009) Pierre LeVan et al.   NEUROIMAGE

EEG-fMRI: Adding to standard evaluations of patients with nonlesional frontal lobe epilepsy

(2009) F. Moeller et al.   NEUROLOGY

In vivo mapping of temporospatial changes in glucose utilization in rat brain during epileptogenesis: an 18F-fluorodeoxyglucose–small animal positron emission tomography study

(2009) Y. Guo et al.   NEUROSCIENCE

Imaging of Peripheral Benzodiazepine Receptor Expression as Biomarkers of Detrimental versus Beneficial Glial Responses in Mouse Models of Alzheimer's and Other CNS Pathologies

(2008) B. Ji et al.   JOURNAL OF NEUROSCIENCE

Layer specific tracing of corticocortical and thalamocortical connectivity in the rodent using manganese enhanced MRI

(2008) Jason Tucciarone et al.   NEUROIMAGE

Neuronuclear Assessment of Patients With Epilepsy

(2008) Karolien Goffin et al.   SEMINARS IN NUCLEAR MEDICINE