Blood-brain barrier dysfunction and epilepsy: Pathophysiologic role and therapeutic approaches

Cliniconeuropathologic correlations show astroglial albumin storage as a common factor in epileptogenic vascular lesions

(2012) Anna Raabe et al.   EPILEPSIA

Spreading convulsions, spreading depolarization and epileptogenesis in human cerebral cortex

(2011) J. P. Dreier et al.   BRAIN

The treatment of super-refractory status epilepticus: a critical review of available therapies and a clinical treatment protocol

(2011) S. Shorvon et al.   BRAIN

Hippocampal damage after prolonged febrile seizure: One case in a consecutive prospective series

(2011) Takuya Tanabe et al.   EPILEPSIA

Iatrogenic seizures during intracranial EEG monitoring

(2011) Julie A. Khoury et al.   EPILEPSIA

Blood-brain barrier dysfunction, status epilepticus, seizures, and epilepsy: A puzzle of a chicken and egg?

(2011) Alon Friedman   EPILEPSIA

Modulation of peripheral cytotoxic cells and ictogenesis in a model of seizures

(2011) Nicola Marchi et al.   EPILEPSIA

Multimodal MRI assessment of damage and plasticity caused by status epilepticus in the rat brain

(2011) Olli Gröhn et al.   EPILEPSIA

Dual-temporal resolution dynamic contrast-enhanced MRI protocol for blood-brain barrier permeability measurement in enhancing multiple sclerosis lesions

(2011) I.O. Jelescu et al.   JOURNAL OF MAGNETIC RESONANCE IMAGING

Ablation of Cyclooxygenase-2 in Forebrain Neurons is Neuroprotective and Dampens Brain Inflammation after Status Epilepticus

(2011) G. E. Serrano et al.   JOURNAL OF NEUROSCIENCE

Brain Infiltration of Leukocytes Contributes to the Pathophysiology of Temporal Lobe Epilepsy

(2011) M. Zattoni et al.   JOURNAL OF NEUROSCIENCE

Epileptiform Activity Induces Vascular Remodeling and Zonula Occludens 1 Downregulation in Organotypic Hippocampal Cultures: Role of VEGF Signaling Pathways

(2011) M. Morin-Brureau et al.   JOURNAL OF NEUROSCIENCE

Autoantibodies associated with diseases of the CNS: new developments and future challenges

(2011) Angela Vincent et al.   LANCET NEUROLOGY

Mechanisms of epileptogenesis and potential treatment targets

(2011) Asla Pitkänen et al.   LANCET NEUROLOGY

Neurological complications of acute ischaemic stroke

(2011) Joyce S Balami et al.   LANCET NEUROLOGY

The role of spreading depression, spreading depolarization and spreading ischemia in neurological disease

(2011) Jens P Dreier   NATURE MEDICINE

Engaging neuroscience to advance translational research in brain barrier biology

(2011) Edward A. Neuwelt et al.   NATURE REVIEWS NEUROSCIENCE

Transplantation of bone marrow mononuclear cells decreases seizure incidence, mitigates neuronal loss and modulates pro-inflammatory cytokine production in epileptic rats

(2011) Zaquer S.M. Costa-Ferro et al.   NEUROBIOLOGY OF DISEASE

Blood-brain Barrier Disruption is Involved in Seizure and Hemianopsia in Nonketotic Hyperglycemia

(2011) Dong Wook Kim et al.   NEUROLOGIST

CXCL12-Mediated Guidance of Migrating Embryonic Stem Cell-Derived Neural Progenitors Transplanted into the Hippocampus

(2011) Nathaniel W. Hartman et al.   PLoS One

Efficacy of Anti-Inflammatory Therapy in a Model of Acute Seizures and in a Population of Pediatric Drug Resistant Epileptics

(2011) Nicola Marchi et al.   PLoS One

Abnormalities of T-lymphocyte subsets in epileptic patients

(2010) Orvar Eeg-Olofsson et al.   ACTA NEUROLOGICA SCANDINAVICA

Hypothermic Circulatory Arrest Increases Permeability of the Blood Brain Barrier in Watershed Areas

(2010) Toru Okamura et al.   ANNALS OF THORACIC SURGERY

Treatment of refractory epilepsy with natalizumab in a patient with multiple sclerosis. Case report

(2010) Stefano Sotgiu et al.   BMC Neurology

Blood–brain barrier damage, but not parenchymal white blood cells, is a hallmark of seizure activity

(2010) Nicola Marchi et al.   BRAIN RESEARCH

Postictal blood–brain barrier breakdown on contrast-enhanced MRI

(2010) Vincent Alvarez et al.   EPILEPSY & BEHAVIOR

The electroclinical-imagiological spectrum and long-term outcome of transient periictal MRI abnormalities

(2010) Nuno Canas et al.   EPILEPSY RESEARCH

Role of CCR5 and its ligands in the control of vascular inflammation and leukocyte recruitment required for acute excitotoxic seizure induction and neural damage

(2010) Jean-Pierre Louboutin et al.   FASEB JOURNAL

Use of dynamic contrast-enhanced MRI to measure subtle blood–brain barrier abnormalities

(2010) Paul A. Armitage et al.   MAGNETIC RESONANCE IMAGING

Toll-like receptor 4 and high-mobility group box-1 are involved in ictogenesis and can be targeted to reduce seizures

(2010) Mattia Maroso et al.   NATURE MEDICINE

The role of inflammation in epilepsy

(2010) Annamaria Vezzani et al.   Nature Reviews Neurology

Imaging of Acute Ischemic Stroke

(2010) Carlos Leiva-Salinas et al.   NEUROIMAGING CLINICS OF NORTH AMERICA

Aquaporins: multifarious roles in brain

(2010) M. Amiry-Moghaddam et al.   NEUROSCIENCE

Automated normalized FLAIR imaging in MRI-negative patients with refractory focal epilepsy

(2009) Niels K. Focke et al.   EPILEPSIA

Diffusion-weighted magnetic resonance imaging in patients with partial status epilepticus

(2009) Carlo Di Bonaventura et al.   EPILEPSIA

Blood–brain barrier breakdown-inducing astrocytic transformation: Novel targets for the prevention of epilepsy

(2009) Alon Friedman et al.   EPILEPSY RESEARCH

Contributions of peripheral inflammation to seizure susceptibility: Cytokines and brain excitability

(2009) Kiarash Riazi et al.   EPILEPSY RESEARCH

Management of the patient with medically refractory epilepsy

(2009) Tiziana Granata et al.   Expert Review of Neurotherapeutics

Chemokine CCL2 and its receptor CCR2 are increased in the hippocampus following pilocarpine-induced status epilepticus

(2009) Maira L Foresti et al.   Journal of Neuroinflammation

Structure and function of the blood–brain barrier

(2009) N. Joan Abbott et al.   NEUROBIOLOGY OF DISEASE

CCR3, CCR2A and macrophage inflammatory protein (MIP)-1α, monocyte chemotactic protein-1 (MCP-1) in the mouse hippocampus during and after pilocarpine-induced status epilepticus (PISE)

(2009) J. H. Xu et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

A comparative study of hydrocortisone versus deflazacort in drug-resistant epilepsy of childhood

(2008) Salvatore Grosso et al.   EPILEPSY RESEARCH

NK and CD4+ T cell changes in blood after seizures in temporal lobe epilepsy

(2008) Sebastian Bauer et al.   EXPERIMENTAL NEUROLOGY

A role for leukocyte-endothelial adhesion mechanisms in epilepsy

(2008) Paolo F Fabene et al.   NATURE MEDICINE

Antagonism of peripheral inflammation reduces the severity of status epilepticus

(2008) Nicola Marchi et al.   NEUROBIOLOGY OF DISEASE

The Blood-Brain Barrier in Health and Chronic Neurodegenerative Disorders

(2008) Berislav V. Zlokovic   NEURON

Microglial activation and TNF  production mediate altered CNS excitability following peripheral inflammation

(2008) K. Riazi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Blood-brain barrier disruption in post-traumatic epilepsy

(2007) O Tomkins et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Innate and adaptive immunity during epileptogenesis and spontaneous seizures: Evidence from experimental models and human temporal lobe epilepsy

(2007) Teresa Ravizza et al.   NEUROBIOLOGY OF DISEASE