Bioengineered in vitro models of leukocyte–vascular interactions

Human Tumor‐Lymphatic Microfluidic Model Reveals Differential Conditioning of Lymphatic Vessels by Breast Cancer Cells

(2020) Jose M. Ayuso et al.   Advanced Healthcare Materials

Principles of Leukocyte Migration Strategies

(2020) Petra Kameritsch et al.   TRENDS IN CELL BIOLOGY

Human organotypic lymphatic vessel model elucidates microenvironment-dependent signaling and barrier function

(2019) Max M. Gong et al.   BIOMATERIALS

Lymphatic Migration of Immune Cells

(2019) Henry R. Hampton et al.   Frontiers in Immunology

Integrated Flow Chamber System for Live Cell Microscopy

(2019) Carlo Kriesi et al.   Frontiers in Bioengineering and Biotechnology

Ultra-thin, aligned, free-standing nanofiber membranes to recapitulate multi-layered blood vessel/tissue interface for leukocyte infiltration study

(2018) Sang Min Park et al.   BIOMATERIALS

Inflamed neutrophils sequestered at entrapped tumor cells via chemotactic confinement promote tumor cell extravasation

(2018) Michelle B. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Endothelial Cell Focal Adhesion Regulates Transendothelial Migration and Subendothelial Crawling of T Cells

(2018) Jaehyun Lee et al.   Frontiers in Immunology

Cellular traffic through afferent lymphatic vessels

(2018) Philipp Schineis et al.   VASCULAR PHARMACOLOGY

Live imaging reveals distinct modes of neutrophil and macrophage migration within interstitial tissues

(2017) Francisco Barros-Becker et al.   JOURNAL OF CELL SCIENCE

Laminar flow downregulates Notch activity to promote lymphatic sprouting

(2017) Dongwon Choi et al.   JOURNAL OF CLINICAL INVESTIGATION

Micro-engineered perfusable 3D vasculatures for cardiovascular diseases

(2017) Nishanth Venugopal Menon et al.   LAB ON A CHIP

Organ-on-a-chip devices advance to market

(2017) Boyang Zhang et al.   LAB ON A CHIP

Organ-On-A-Chip Platforms: A Convergence of Advanced Materials, Cells, and Microscale Technologies

(2017) Samad Ahadian et al.   Advanced Healthcare Materials

Locally Triggered Release of the Chemokine CCL21 Promotes Dendritic Cell Transmigration across Lymphatic Endothelia

(2017) Kari Vaahtomeri et al.   Cell Reports

A robust in vitro model for trans-lymphatic endothelial migration

(2017) Yanbao Xiong et al.   Scientific Reports

Turning behaviors of T cells climbing up ramp-like structures are regulated by myosin light chain kinase activity and lamellipodia formation

(2017) Kwang Hoon Song et al.   Scientific Reports

Biomimetic channel modeling local vascular dynamics of pro-inflammatory endothelial changes

(2016) Antony Thomas et al.   Biomicrofluidics

The role of lymphangiogenesis and angiogenesis in tumor metastasis

(2016) Roman Paduch   CELLULAR ONCOLOGY

Intralymphatic CCL21 Promotes Tissue Egress of Dendritic Cells through Afferent Lymphatic Vessels

(2016) Erica Russo et al.   Cell Reports

Recapitulation of in vivo-like neutrophil transendothelial migration using a microfluidic platform

(2015) Xiaojie Wu et al.   ANALYST

An in vitro model of the tumor–lymphatic microenvironment with simultaneous transendothelial and luminal flows reveals mechanisms of flow enhanced invasion

(2015) M. Pisano et al.   Integrative Biology

A novel device to concurrently assess leukocyte extravasation and interstitial migration within a defined 3D environment

(2015) Raffaella Molteni et al.   LAB ON A CHIP

Review: in vitro microvessel models

(2015) Max I. Bogorad et al.   LAB ON A CHIP

Organs-on-chips at the frontiers of drug discovery

(2015) Eric W. Esch et al.   NATURE REVIEWS DRUG DISCOVERY

Microcirculation-on-a-Chip: A Microfluidic Platform for Assaying Blood- and Lymphatic-Vessel Permeability

(2015) Miwa Sato et al.   PLoS One

Neutrophil trails guide influenza-specific CD8+ T cells in the airways

(2015) K. Lim et al.   SCIENCE

Leukocyte Migration into Inflamed Tissues

(2014) Sussan Nourshargh et al.   IMMUNITY

T cells sense biophysical cues using lamellipodia and filopodia to optimize intraluminal path finding

(2014) Kwang Hoon Song et al.   Integrative Biology

The chemokine CX3CL1 promotes trafficking of dendritic cells through inflamed lymphatics

(2013) L. A. Johnson et al.   JOURNAL OF CELL SCIENCE

Perivascular macrophages mediate neutrophil recruitment during bacterial skin infection

(2013) Arby Abtin et al.   NATURE IMMUNOLOGY

Initial Afferent Lymphatic Vessels Controlling Outbound Leukocyte Traffic from Skin to Lymph Nodes

(2013) Alvaro Teijeira et al.   Frontiers in Immunology

Pericytes support neutrophil subendothelial cell crawling and breaching of venular walls in vivo

(2012) Doris Proebstl et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A versatile assay for monitoring in vivo-like transendothelial migration of neutrophils

(2012) Sewoon Han et al.   LAB ON A CHIP

Three-dimensional microfluidic model for tumor cell intravasation and endothelial barrier function

(2012) I. K. Zervantonakis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dynamics of T cells on endothelial layers aligned by nanostructured surfaces

(2011) Kwang Hoon Song et al.   BIOMATERIALS

Tissue inflammation modulates gene expression of lymphatic endothelial cells and dendritic cell migration in a stimulus-dependent manner

(2011) B. Vigl et al.   BLOOD

Role of shear stress and stretch in vascular mechanobiology

(2011) D. Lu et al.   Journal of the Royal Society Interface

Effects of Shear Stress and Stretch on Endothelial Function

(2010) Joji Ando et al.   ANTIOXIDANTS & REDOX SIGNALING

Inflammation-induced secretion of CCL21 in lymphatic endothelium is a key regulator of integrin-mediated dendritic cell transmigration

(2010) Louise A. Johnson et al.   INTERNATIONAL IMMUNOLOGY

Breaching multiple barriers: leukocyte motility through venular walls and the interstitium

(2010) Sussan Nourshargh et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mechanical modes of ‘amoeboid’ cell migration

(2009) Tim Lämmermann et al.   CURRENT OPINION IN CELL BIOLOGY

Interstitial leukocyte migration and immune function

(2008) Peter Friedl et al.   NATURE IMMUNOLOGY