Article
Biotechnology & Applied Microbiology
H. S. Rohith, Muthukumar Serva Peddha, Prakash Motiram Halami
Summary: This study aimed to analyze the probiotic efficiency of Bacillus licheniformis and Bifidobacterium breve on TNBS-induced ulcerative colitis in Wistar rats. The combination of bacteria and C-reactive protein inhibited nitric oxide production and reduced the tumor-like structure in the colon. Probiotic bacteria also reduced liver damage and expression of GATA3, while increasing expression of antioxidant genes. The specific cytokines related to Th2-driven immune response were reduced upon feeding the bacteria, suggesting that B. licheniformis and Bf. breve can reduce Th2-driven immune response.
PROBIOTICS AND ANTIMICROBIAL PROTEINS
(2023)
Review
Microbiology
Svetoslav Dimitrov Todorov, Iskra Vitanova Ivanova, Igor Popov, Richard Weeks, Michael Leonidas Chikindas
Summary: Representatives of the genus Bacillus are versatile microorganisms with widespread applications in traditional fermentation and modern biotechnology. They have numerous beneficial properties, serving as starter cultures for fermented foods, producers of enzymes, antibiotics, and bioactive peptides, and as probiotics for humans and animals. Despite their well-documented benefits, questions regarding their safety and spore formation in practical applications have been raised, prompting further exploration in this review.
CRITICAL REVIEWS IN MICROBIOLOGY
(2022)
Article
Food Science & Technology
Marjolein M. P. Oerlemans, Renate Akkerman, Michela Ferrari, Marthe T. C. Walvoort, Paul de Vos
Summary: Bacterial exopolysaccharides (EPS) play a crucial role in intestinal health by influencing bacterial interactions with the host, with specific monosaccharides or linkages possibly being related to their effects.
JOURNAL OF FUNCTIONAL FOODS
(2021)
Article
Microbiology
Margherita D'Alessandro, Carola Parolin, Silvia Patrignani, Gilda Sottile, Patrizio Antonazzo, Beatrice Vitali, Rosalba Lanciotti, Francesca Patrignani
Summary: This study focuses on the isolation and characterization of lactobacilli/bifidobacteria from human breast milk to find new probiotic candidates for food products. The breast milk strains demonstrate good adhesion to intestinal cells, antagonistic activity against food spoilage and pathogenic species, and the potential to release aroma compounds associated with sensory quality of dairy products.
Article
Microbiology
Silvia Saturio, Alicja M. Nogacka, Guadalupe M. Alvarado-Jasso, Nuria Salazar, Clara G. de los Reyes-Gavilan, Miguel Gueimonde, Silvia Arboleya
Summary: Bifidobacteria are crucial microorganisms during infancy, playing a dominant role in the healthy development of breastfed infants. The different species and quantities of Bifidobacteria have been shown to be important for infant health, with reduced levels potentially linked to infant diseases. Bifidobacterium strains are extensively studied for their probiotic properties, with research on their use as probiotics in neonates.
Review
Food Science & Technology
S. Mithul Aravind, Santad Wichienchot, Rong Tsao, S. Ramakrishnan, S. Chakkaravarthi
Summary: In the past two decades, there has been intensive research on the beneficial health roles of dietary polyphenols in preventing oxidative stress related chronic diseases. As our understanding of the role of gut microbiota advances, the need to examine the prebiotic role of dietary polyphenols has emerged. Further research should focus on the importance of human trials and the links of polyphenols-gut microbiota-nerve-brain to unlock the mechanisms behind the observed benefits of dietary polyphenols.
FOOD RESEARCH INTERNATIONAL
(2021)
Review
Microbiology
Diana Luise, Paolo Bosi, Lena Raff, Laura Amatucci, Sara Virdis, Paolo Trevisi
Summary: Bacillus strains as probiotics in pigs and poultry have been shown to promote growth and reduce diseases, potentially replacing the misuse of antibiotics and positively impacting health and performance.
FRONTIERS IN MICROBIOLOGY
(2022)
Review
Biochemistry & Molecular Biology
Majid Mounir, Amal Ibijbijen, Kawtar Farih, Holy N. Rabetafika, Hary L. Razafindralambo
Summary: Antioxidants play a vital role in maintaining the longevity and health of humans and animals. Microbial-based products, such as probiotics and their derivatives, have been recognized for their antioxidant properties. Synbiotics combining probiotics with prebiotics can generate superior antioxidant compounds that have positive effects on human and animal health.
Article
Biochemistry & Molecular Biology
Veronica Arreaza-Gil, Ivan Escobar-Martinez, Begona Muguerza, Gerard Aragones, Manuel Suarez, Cristina Torres-Fuentes, Anna Arola-Arnal
Summary: Polyphenols have beneficial health effects, including anti-obesity properties. This study found that the gut microbiota and photoperiod have an impact on the functionality of polyphenols in an obesogenic context. Under L18 conditions, grape seed proanthocyanidin extract (GSPE) decreased body weight gain and fat depots, and the gut microbiota composition was strongly altered. These findings suggest that the functionality of polyphenols is modulated by the gut microbiota in a photoperiod-dependent manner.
Review
Food Science & Technology
Meijun Zeng, Jan-Peter van Pijkeren, Xuejun Pan
Summary: Prebiotics are used to modulate gut microbiota and improve host health. Gluco-oligosaccharides (GlcOS) have been found to exert prebiotic potentials due to their selective fermentation by beneficial gut bacteria. However, the prebiotic effects of GlcOS vary due to their complex structure. This review provides an overview of GlcOS as potential prebiotics, covering their synthesis, purification, structural characterization, and prebiotic effect evaluation.
COMPREHENSIVE REVIEWS IN FOOD SCIENCE AND FOOD SAFETY
(2023)
Review
Food Science & Technology
Shenia Santos Monteiro, Veronica Macario de Oliveira, Matheus Augusto de Bittencourt Pasquali
Summary: The relationship between food and human health drives the search for knowledge of food components that are related to these benefits. The scientific community shows a growing interest in the knowledge of the interactions between components of citrus fruits and probiotics to develop ways to improve the quality of the food produced. This bibliometric review examines scientific publications on the potential of probiotics in citrus fermentation and discusses the importance and future trends of plant-based products as an alternative to the dairy market in the functional food group.
Article
Biotechnology & Applied Microbiology
H. S. Rohith, Prakash Motiram Halami
Summary: The study evaluates the effects of a combination of Bacillus licheniformis and Bifidobacterium breve on the gene expression and immune response of HT-29 cells. The combination of these probiotic bacteria showed anti-inflammatory activity and improved the gastrointestinal environment, making it a promising treatment for intestinal disorders.
PROBIOTICS AND ANTIMICROBIAL PROTEINS
(2023)
Article
Microbiology
J. A. Maldonado-Lobon, R. Blanco-Rojo, J. Maldonado, M. A. Ali, M. Almazan, A. Suanes-Cabello, E. Callejon, R. Jaldo, M. R. Benavides, A. M. Negrillo, A. Sanudo, C. Rodriguez, O. Banuelos, J. Fonolla, M. Olivares
Summary: By comparing different treatment options, it was found that Bifidobacterium breve CECT7263 had an earlier and more robust effect on infantile colic, significantly reducing daily crying time, improving night sleep, and making parents feel more positive.
BENEFICIAL MICROBES
(2021)
Review
Microbiology
Qing Yang, Zhenlong Wu
Summary: Pets, especially dogs and cats, play a significant role in the lives of humans, and their health has gained increasing attention. The gut microbiota, which has various functions, is crucial for the overall health of pets. Imbalance in the gut microbiota has been associated with diseases in both humans and animals. Probiotics have been introduced into pet foods and supplements to modulate the gut microbiota and improve pet health. Studies have shown positive effects of probiotics on gut health and the treatment of intestinal diseases in dogs and cats, although the underlying mechanisms remain unclear.
Article
Food Science & Technology
Guangting Xie, Yating Zhu, Zhongxuan Zhong, Qianping Du, Yuxin Wu, Ke Xing, Mingqing Zhang, Hu Shu
Summary: This study evaluated the probiotic characteristics of Bacillus cereus G1-11 isolated from the gut of hybrid groupers by integrating genomics and phenotypic characteristics. Genome mining revealed gene clusters responsible for acid and bile tolerance, intestinal adhesion, and colonisation. In vitro experiments showed G1-11's ability to survive gastrointestinal transit, as well as its antioxidant and antibacterial capabilities. Results suggest that B. cereus G1-11 has the potential to enhance the growth and immunity of hybrid groupers.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2023)
Article
Microbiology
Aditi Goel, Prakash M. Halami, Jyoti Prakash Tamang
FRONTIERS IN MICROBIOLOGY
(2020)
Review
Biotechnology & Applied Microbiology
Aravind Sundararaman, Mousumi Ray, P. Ravindra, Prakash M. Halami
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
(2020)
Article
Biotechnology & Applied Microbiology
Ann Catherine Archer, Serva Peddha Muthukumar, Prakash Motiram Halami
Summary: The study investigated the effects of potential probiotic Lactobacillus fermentum on intestinal markers of inflammation in diabetes and obesity models. Results showed improved oral glucose tolerance, plasma insulin levels, and reduced inflammatory tone, suggesting Lact. fermentum as a potential probiotic for lifestyle-related disorders.
PROBIOTICS AND ANTIMICROBIAL PROTEINS
(2021)
Article
Chemistry, Multidisciplinary
Meena Kumari Palani Kumar, Prakash Motiram Halami, Muthukumar Serva Peddha
Summary: The probiotic strain Lactobacillus fermentum MCC2760 has shown beneficial effects in high-cholesterol diet-fed mice, including reducing serum lipids, anti-inflammatory properties, and improving gut barrier function. These findings highlight the potential of probiotic supplementation in managing hypercholesterolemia.
Article
Biology
Salwa Naushin, Viren Sardana, Rajat Ujjainiya, Nitin Bhatheja, Rintu Kutum, Akash Kumar Bhaskar, Shalini Pradhan, Satyartha Prakash, Raju Khan, Birendra Singh Rawat, Karthik Bharadwaj Tallapaka, Mahesh Anumalla, Giriraj Ratan Chandak, Amit Lahiri, Susanta Kar, Shrikant Ramesh Mulay, Madhav Nilakanth Mugale, Mrigank Srivastava, Shaziya Khan, Anjali Srivastava, Bhawana Tomar, Murugan Veerapandian, Ganesh Venkatachalam, Selvamani Raja Vijayakumar, Ajay Agarwal, Dinesh Gupta, Prakash M. Halami, Muthukumar Serva Peddha, Gopinath M. Sundaram, Ravindra P. Veeranna, Anirban Pal, Vinay Kumar Agarwal, Anil Ku Maurya, Ranvijay Kumar Singh, Ashok Kumar Raman, Suresh Kumar Anandasadagopan, Parimala Karuppanan, Subramanian Venkatesan, Harish Kumar Sardana, Anamika Kothari, Rishabh Jain, Anupama Thakur, Devendra Singh Parihar, Anas Saifi, Jasleen Kaur, Virendra Kumar, Avinash Mishra, Iranna Gogeri, Geethavani Rayasam, Praveen Singh, Rahul Chakraborty, Gaura Chaturvedi, Pinreddy Karunakar, Rohit Yadav, Sunanda Singhmar, Dayanidhi Singh, Sharmistha Sarkar, Purbasha Bhattacharya, Sundaram Acharya, Vandana Singh, Shweta Verma, Drishti Soni, Surabhi Seth, Sakshi Vashisht, Sarita Thakran, Firdaus Fatima, Akash Pratap Singh, Akanksha Sharma, Babita Sharma, Manikandan Subramanian, Yogendra S. Padwad, Vipin Hallan, Vikram Patial, Damanpreet Singh, Narendra Vijay Tripude, Partha Chakrabarti, Sujay Krishna Maity, Dipyaman Ganguly, Jit Sarkar, Sistla Ramakrishna, Balthu Narender Kumar, Kiran A. Kumar, Sumit G. Gandhi, Piyush Singh Jamwal, Rekha Chouhan, Vijay Lakshmi Jamwal, Nitika Kapoor, Debashish Ghosh, Ghanshyam Thakkar, Umakanta Subudhi, Pradip Sen, Saumya Ray Chaudhury, Rashmi Kumar, Pawan Gupta, Amit Tuli, Deepak Sharma, Rajesh P. Ringe, D. Amarnarayan, Mahesh Kulkarni, Dhansekaran Shanmugam, Mahesh S. Dharne, Sayed G. Dastager, Rakesh Joshi, Amita P. Patil, Sachin N. Mahajan, Abujunaid Habib Khan, Vasudev Wagh, Rakesh Kumar Yadav, Ajinkya Khilari, Mayuri Bhadange, Arvindkumar H. Chaurasiya, Shabda E. Kulsange, Krishna Khairnar, Shilpa Paranjape, Jatin Kalita, Narahari G. Sastry, Tridip Phukan, Prasenjit Manna, Wahengbam Romi, Pankaj Bharali, Dibyajyoti Ozah, Ravi Kumar Sahu, Elapavalooru Vssk Babu, Rajeev Sukumaran, Aiswarya R. Nair, Prajeesh Kooloth Valappil, Anoop Puthiyamadam, Adarsh Velayudhanpillai, Kalpana Chodankar, Samir Damare, Yennapu Madhavi, Ved Varun Aggarwal, Sumit Dahiya, Anurag Agrawal, Debasis Dash, Shantanu Sengupta
Summary: The Council of Scientific and Industrial Research in India conducted a serosurvey in August and September 2020 to understand the spread of SARS-CoV2 and found that some individuals may be infected with the virus even without symptoms. Personal factors such as high-exposure work, use of public transport, non-smoking, non-vegetarian diet, and blood type B are associated with higher odds of seropositivity.
Article
Microbiology
Aravind Sundararaman, Kanika Bansal, Jameema Sidhic, Prabhu Patil, Prakash M. Halami
Summary: Bifidobacterium longum NCIM 5672 is a probiotic strain isolated from Indian infant feces, and its probiotic properties and acid-tolerance mechanism were determined through whole-genome sequencing. Genome analysis identified candidate acid-tolerance-associated genes, as well as genes associated with immunomodulation and cell adhesion, with RT-qPCR results supporting the role of these genes in acid tolerance. This study provides insights for selecting acid-resistant strains for the food industry and enhancing the industrial applications and health-promoting properties of this species.
ARCHIVES OF MICROBIOLOGY
(2021)
Review
Biology
Ashwini Manjunath, Surya Chandra Rao Thumu, Sumana Kumar, Prakash Motiram Halami
Summary: Heteroresistance is a phenomenon where a subset of bacterial cells shows higher resistance towards antibiotics, making it difficult to treat infections caused by these bacteria due to challenges in identification and study of subpopulations.
Article
Microbiology
Basista Rabina Sharma, Dharana Jayant, Kumari Rajshee, Yashika Singh, Prakash M. Halami
Summary: This study aimed to characterize natural antibiotics or lantibiotics from unconventional sources and their antibacterial spectrum. LAB producing bacteriocin were isolated from traditional fermented foods, with 129 cultures found to produce antimicrobial compounds. The identified Nisin-like bacteriocin showed inhibitory effects against foodborne pathogens and drug-resistant bacteria.
CURRENT MICROBIOLOGY
(2021)
Review
Biotechnology & Applied Microbiology
Mousumi Ray, Ashwini Manjunath, Prakash M. Halami
Summary: Antimicrobial resistance poses a significant challenge to global health. Inappropriate use of antibiotics, particularly in farming, has led to resistance to last-resort antibiotics such as colistin and polymyxin B. The mechanism of resistance to these antibiotics involves genetic alterations in chromosomal genes, as well as the presence of a mobile colistin/polymyxin B resistance gene (mcr) in Enterobacteriales. It is crucial to increase surveillance for detecting resistance to these antibiotics and to consider the implications of their usage in food safety.
JOURNAL OF ANTIBIOTICS
(2022)
Review
Biotechnology & Applied Microbiology
Rwivoo Baruah, Mousumi Ray, Prakash M. Halami
Summary: In recent years, there has been a rapid increase in the recognition of fermented foods as functional foods that provide health benefits in specific disease conditions. The health benefits of fermented foods are attributed to the presence of probiotic microbes and bioactive compounds formed during fermentation. The impact of fermented foods on conditions such as diabetes, cardiovascular disease, obesity, gastrointestinal disorder, cancer, and neurodegenerative disorders has been the focus of numerous studies using animal models and human clinical trials.
JOURNAL OF APPLIED MICROBIOLOGY
(2022)
Article
Biotechnology & Applied Microbiology
H. S. Rohith, Prakash Motiram Halami
Summary: The study evaluates the effects of a combination of Bacillus licheniformis and Bifidobacterium breve on the gene expression and immune response of HT-29 cells. The combination of these probiotic bacteria showed anti-inflammatory activity and improved the gastrointestinal environment, making it a promising treatment for intestinal disorders.
PROBIOTICS AND ANTIMICROBIAL PROTEINS
(2023)
Article
Food Science & Technology
M. Ashwini, Mousumi Ray, K. Sumana, Prakash M. Halami
Summary: This study investigates the prevalence of antibiotic resistance in lactic acid bacteria (LAB) and identifies diverse phenotypic and genotypic MLS resistance among LAB species isolated from food samples and food-producing animals. The results suggest that food samples and food-producing animals can be potential sources of antibiotic-resistant LAB, highlighting the importance of raising awareness about antibiotic use to prevent resistance spread.
JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE
(2023)
Correction
Biotechnology & Applied Microbiology
Ann Catherine Archer, Serva Peddha Muthukumar, Prakash Motiram Halami
PROBIOTICS AND ANTIMICROBIAL PROTEINS
(2023)
Article
Food Science & Technology
Aditi Goel, Attar Singh Chauhan, Prakash M. Halami
Summary: This study developed a vegetable-based probiotic carrot nectar by incorporating Lactiplantibacillus plantarum MCC5231 into carrot nectar. The probiotic carrot nectar maintained high viability under refrigerated conditions and exhibited antimicrobial activity and high vitamin A content, providing several health benefits.
JOURNAL OF FOOD MEASUREMENT AND CHARACTERIZATION
(2023)