An Antibody-like Polymeric Nanoparticle Removes Intratumoral Galectin-1 to Enhance Antitumor T-Cell Responses in Cancer Immunotherapy

Dual functionalized brain-targeting nanoinhibitors restrain temozolomide-resistant glioma via attenuating EGFR and MET signaling pathways

(2020) Xiangqi Meng et al.   Nature Communications

Neuroprotective Nanoscavenger Induces Coaggregation of β-Amyloid and Facilitates Its Clearance in Alzheimer’s Disease Brain

(2020) Yu Zhao et al.   CCS Chemistry

Transforming Growth Factor-β Signaling in Immunity and Cancer

(2019) Eduard Batlle et al.   IMMUNITY

Cancer nanomedicine for combination cancer immunotherapy

(2019) Jutaek Nam et al.   Nature Reviews Materials

In Situ Modification of the Tumor Cell Surface with Immunomodulating Nanoparticles for Effective Suppression of Tumor Growth in Mice

(2019) Chunxiong Zheng et al.   ADVANCED MATERIALS

Targeting galectin-1 inhibits pancreatic cancer progression by modulating tumor–stroma crosstalk

(2018) Carlos A. Orozco et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A self-destructive nanosweeper that captures and clears amyloid β-peptides

(2018) Qiang Luo et al.   Nature Communications

Nanocomposites Inhibit the Formation, Mitigate the Neurotoxicity, and Facilitate the Removal of β-Amyloid Aggregates in Alzheimer’s Disease Mice

(2018) Yu Zhao et al.   NANO LETTERS

The future of immune checkpoint cancer therapy after PD-1 and CTLA-4

(2017) Andrew W Hahn et al.   Immunotherapy

A polymer nanoparticle with engineered affinity for a vascular endothelial growth factor (VEGF165)

(2017) Hiroyuki Koide et al.   Nature Chemistry

Dectin 1 activation on macrophages by galectin 9 promotes pancreatic carcinoma and peritumoral immune tolerance

(2017) Donnele Daley et al.   NATURE MEDICINE

Translating the ‘Sugar Code’ into Immune and Vascular Signaling Programs

(2017) Juan P. Cerliani et al.   TRENDS IN BIOCHEMICAL SCIENCES

Multivalent effect of glycopolypeptide based nanoparticles for galectin binding

(2016) Colin Bonduelle et al.   CHEMICAL COMMUNICATIONS

Enhancing T cell therapy by overcoming the immunosuppressive tumor microenvironment

(2016) Ainhoa Arina et al.   SEMINARS IN IMMUNOLOGY

Immune Checkpoint Targeting in Cancer Therapy: Toward Combination Strategies with Curative Potential

(2015) Padmanee Sharma et al.   CELL

Combination cancer immunotherapies tailored to the tumour microenvironment

(2015) Mark J. Smyth et al.   Nature Reviews Clinical Oncology

The future of immune checkpoint therapy

(2015) P. Sharma et al.   SCIENCE

A monosaccharide-modified peptide phage library for screening of ligands to carbohydrate-binding proteins

(2013) Kanako Arai et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Calling the next generation of affinity reagents

(2013) Vivien Marx   NATURE METHODS

Regulatory Circuits Mediated by Lectin-Glycan Interactions in Autoimmunity and Cancer

(2012) Gabriel A. Rabinovich et al.   IMMUNITY

Tumor Galectin-1 Mediates Tumor Growth and Metastasis through Regulation of T-Cell Apoptosis

(2011) A. Banh et al.   CANCER RESEARCH

Affinity Purification of Multifunctional Polymer Nanoparticles

(2010) Yu Hoshino et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Decreased Clearance of CNS  -Amyloid in Alzheimer's Disease

(2010) K. G. Mawuenyega et al.   SCIENCE

Multivalent antibodies: when design surpasses evolution

(2010) Ángel M. Cuesta et al.   TRENDS IN BIOTECHNOLOGY

Lectin Recognizable Biomaterials Synthesized via Nitroxide-Mediated Polymerization of a Methacryloyl Galactose Monomer

(2009) S. R. Simon Ting et al.   MACROMOLECULES

Peptide Imprinted Polymer Nanoparticles: A Plastic Antibody

(2008) Yu Hoshino et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY