Initial Identification of UDP-Glucose Dehydrogenase as a Prognostic Marker in Breast Cancer Patients, Which Facilitates Epirubicin Resistance and Regulates Hyaluronan Synthesis in MDA-MB-231 Cells

Sirtuin 1 reduces hyaluronan synthase 2 expression by inhibiting nuclear translocation of NF-kB and expression of the long-non coding RNA HAS2-AS1

(2020) Ilaria Caon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SETD3 acts as a prognostic marker in breast cancer patients and modulates the viability and invasion of breast cancer cells

(2020) Nourhan Hassan et al.   Scientific Reports

Cell Energy Metabolism and Hyaluronan Synthesis

(2020) Ilaria Caon et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Hyaluronan Metabolism is Associated with DNA Repair Genes in Breast and Colorectal Cancer. Screening of Potential Progression Markers Using qPCR

(2020) Ina Sevic et al.   Biomedicines

Hyaluronan: molecular size‐dependent signaling and biological functions in inflammation and cancer

(2019) Anastasia G. Tavianatou et al.   FEBS Journal

Dissecting the role of hyaluronan synthases in the tumor microenvironment

(2019) Alberto Passi et al.   FEBS Journal

Hyaluronan preconditioning of monocytes/macrophages affects their angiogenic behavior and regulation of TSG ‐6 expression in a tumor type‐specific manner

(2019) Fiorella M. Spinelli et al.   FEBS Journal

Autophagy dysfunctions associated with cancer cells and their therapeutic implications

(2019) Aurelian Udristioiu et al.   BIOMEDICINE & PHARMACOTHERAPY

Proteoglycans and glycosaminoglycans as regulators of cancer stem cell function and therapeutic resistance

(2019) Daiana Vitale et al.   FEBS Journal

UDP-glucose accelerates SNAI1 mRNA decay and impairs lung cancer metastasis

(2019) Xiongjun Wang et al.   NATURE

Revisiting the hallmarks of cancer: The role of hyaluronan

(2019) Ilaria Caon et al.   SEMINARS IN CANCER BIOLOGY

Emerging roles of ECM remodeling processes in cancer

(2019) Vishnu Mohan et al.   SEMINARS IN CANCER BIOLOGY

Activated hyaluronan metabolism in the tumor matrix — Causes and consequences

(2018) Markku I. Tammi et al.   MATRIX BIOLOGY

Effects of mutations in the post-translational modification sites on the trafficking of hyaluronan synthase 2 (HAS2)

(2018) R.M. Melero-Fernandez de Mera et al.   MATRIX BIOLOGY

STRING v11: protein–protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets

(2018) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

Co-treatment of tumor cells with hyaluronan plus doxorubicin affects endothelial cell behavior independently of VEGF expression

(2018) Daiana L. Vitale et al.   Oncotarget

UDP-sugar substrates of HAS3 regulate its O-GlcNAcylation, intracellular traffic, extracellular shedding and correlate with melanoma progression

(2016) Ashik Jawahar Deen et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

MDA-MB-231 breast cancer cell viability, motility and matrix adhesion are regulated by a complex interplay of heparan sulfate, chondroitin−/dermatan sulfate and hyaluronan biosynthesis

(2016) Manuela Viola et al.   GLYCOCONJUGATE JOURNAL

4-Methylumbelliferone inhibits hepatocellular carcinoma growth by decreasing IL-6 production and angiogenesis

(2015) Flavia Piccioni et al.   GLYCOBIOLOGY

Hyaluronan: Biosynthesis and signaling

(2014) Davide Vigetti et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

UDP-glucose dehydrogenase modulates proteoglycan synthesis in articular chondrocytes: its possible involvement and regulation in osteoarthritis

(2014) Yinxian Wen et al.   ARTHRITIS RESEARCH & THERAPY

Developmental and Pathological Angiogenesis

(2011) Alicia S. Chung et al.   Annual Review of Cell and Developmental Biology

Autophagy protects breast cancer cells from epirubicin-induced apoptosis and facilitates epirubicin-resistance development

(2011) Wei-Liang Sun et al.   Autophagy

Jetset: selecting the optimal microarray probe set to represent a gene

(2011) Qiyuan Li et al.   BMC BIOINFORMATICS

RecurrenceOnline: an online analysis tool to determine breast cancer recurrence and hormone receptor status using microarray data

(2011) Balázs Győrffy et al.   BREAST CANCER RESEARCH AND TREATMENT

UDP-glucose dehydrogenase: structure and function of a potential drug target

(2010) Sigrid Egger et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Down-regulation of UDP-glucose dehydrogenase affects glycosaminoglycans synthesis and motility in HCT-8 colorectal carcinoma cells

(2010) Tsung-Pao Wang et al.   EXPERIMENTAL CELL RESEARCH

Triple-Negative Breast Cancer

(2010) William D. Foulkes et al.   NEW ENGLAND JOURNAL OF MEDICINE

An online survival analysis tool to rapidly assess the effect of 22,277 genes on breast cancer prognosis using microarray data of 1,809 patients

(2009) Balazs Györffy et al.   BREAST CANCER RESEARCH AND TREATMENT

Androgen-Stimulated UDP-Glucose Dehydrogenase Expression Limits Prostate Androgen Availability without Impacting Hyaluronan Levels

(2009) Q. Wei et al.   CANCER RESEARCH

Udp-glucose dehydrogenase as a novel field-specific candidate biomarker of prostate cancer

(2009) Dali Huang et al.   INTERNATIONAL JOURNAL OF CANCER