UDP-sugar substrates of HAS3 regulate its O-GlcNAcylation, intracellular traffic, extracellular shedding and correlate with melanoma progression
Published 2016 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
UDP-sugar substrates of HAS3 regulate its O-GlcNAcylation, intracellular traffic, extracellular shedding and correlate with melanoma progression
Authors
Keywords
4MU, Mannose, Glucosamine, GNPDA, UGDH, OGT
Journal
CELLULAR AND MOLECULAR LIFE SCIENCES
Volume 73, Issue 16, Pages 3183-3204
Publisher
Springer Nature
Online
2016-02-16
DOI
10.1007/s00018-016-2158-5
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Hyaluronan synthase 3 (HAS3) overexpression downregulates MV3 melanoma cell proliferation, migration and adhesion
- (2015) Piia Takabe et al. EXPERIMENTAL CELL RESEARCH
- A novel role of low molecular weight hyaluronan in breast cancer metastasis
- (2015) Man Wu et al. FASEB JOURNAL
- Interleukin-1β-induced Reduction of CD44 Ser-325 Phosphorylation in Human Epidermal Keratinocytes Promotes CD44 Homomeric Complexes, Binding to Ezrin, and Extended, Monocyte-adhesive Hyaluronan Coats
- (2015) Tiina Jokela et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Diabetes-associated dysregulation ofO-GlcNAcylation in rat cardiac mitochondria
- (2015) Partha S. Banerjee et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Interactions between Hyaluronan and Its Receptors (CD44, RHAMM) Regulate the Activities of Inflammation and Cancer
- (2015) Suniti Misra et al. Frontiers in Immunology
- Accumulation of small hyaluronan oligosaccharides in tumour interstitial fluid correlates with lymphatic invasion and lymph node metastasis
- (2014) A Schmaus et al. BRITISH JOURNAL OF CANCER
- Rab10-mediated Endocytosis of the Hyaluronan Synthase HAS3 Regulates Hyaluronan Synthesis and Cell Adhesion to Collagen
- (2014) Ashik Jawahar Deen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Natural Antisense Transcript for Hyaluronan Synthase 2 (HAS2-AS1) Induces Transcription of HAS2 via ProteinO-GlcNAcylation
- (2014) Davide Vigetti et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- STIM1- and Orai1-mediated Ca2+oscillation orchestrates invadopodium formation and melanoma invasion
- (2014) Jianwei Sun et al. JOURNAL OF CELL BIOLOGY
- Bladder Cancer Exosomes Contain EDIL-3/Del1 and Facilitate Cancer Progression
- (2014) Carla J. Beckham et al. JOURNAL OF UROLOGY
- The dynamic metabolism of hyaluronan regulates the cytosolic concentration of UDP-GlcNAc
- (2014) Vincent C. Hascall et al. MATRIX BIOLOGY
- Accumulation of Extracellular Hyaluronan by Hyaluronan Synthase 3 Promotes Tumor Growth and Modulates the Pancreatic Cancer Microenvironment
- (2014) Anne Kultti et al. Biomed Research International
- Inverse expression of hyaluronidase 2 and hyaluronan synthases 1–3 is associated with reduced hyaluronan content in malignant cutaneous melanoma
- (2013) Siiskonen Hanna et al. BMC CANCER
- Hyaluronan production enhances shedding of plasma membrane-derived microvesicles
- (2013) Kirsi Rilla et al. EXPERIMENTAL CELL RESEARCH
- Deregulation of hyaluronan synthesis, degradation and binding promotes breast cancer
- (2013) P. Heldin et al. JOURNAL OF BIOCHEMISTRY
- Hyaluronan Synthase 1 (HAS1) Requires Higher Cellular UDP-GlcNAc Concentration than HAS2 and HAS3
- (2013) Kirsi Rilla et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Borate-aided anion exchange high-performance liquid chromatography of uridine diphosphate-sugars in brain, heart, adipose and liver tissues
- (2013) Sanna Oikari et al. JOURNAL OF CHROMATOGRAPHY A
- High-molecular-mass hyaluronan mediates the cancer resistance of the naked mole rat
- (2013) Xiao Tian et al. NATURE
- Role of UDP-N-Acetylglucosamine (GlcNAc) andO-GlcNAcylation of Hyaluronan Synthase 2 in the Control of Chondroitin Sulfate and Hyaluronan Synthesis
- (2012) Davide Vigetti et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Multiple post-translational modifications regulate E-cadherin transport during apoptosis
- (2012) F. Geng et al. JOURNAL OF CELL SCIENCE
- The Hyaluronan Synthase Catalyzes the Synthesis and Membrane Translocation of Hyaluronan
- (2012) Caitlin Hubbard et al. JOURNAL OF MOLECULAR BIOLOGY
- Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET
- (2012) Héctor Peinado et al. NATURE MEDICINE
- Transcriptional and post-translational regulation of hyaluronan synthesis
- (2011) Raija H. Tammi et al. FEBS Journal
- HAS3-induced accumulation of hyaluronan in 3D MDCK cultures results in mitotic spindle misorientation and disturbed organization of epithelium
- (2011) Kirsi Rilla et al. HISTOCHEMISTRY AND CELL BIOLOGY
- Cellular Content of UDP-N-acetylhexosamines Controls Hyaluronan Synthase 2 Expression and Correlates withO-LinkedN-Acetylglucosamine Modification of Transcription Factors YY1 and SP1
- (2011) Tiina A. Jokela et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Glycosaminoglycans and Glucose Prevent Apoptosis in 4-Methylumbelliferone-treated Human Aortic Smooth Muscle Cells
- (2011) Davide Vigetti et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Hyaluronan and versican in the control of human T-lymphocyte adhesion and migration
- (2011) Stephen P. Evanko et al. MATRIX BIOLOGY
- Hyaluronan as an Immune Regulator in Human Diseases
- (2011) Dianhua Jiang et al. PHYSIOLOGICAL REVIEWS
- Hyaluronan synthases (HAS1-3) and hyaluronidases (HYAL1-2) in the accumulation of hyaluronan in endometrioid endometrial carcinoma
- (2010) Timo K Nykopp et al. BMC CANCER
- Hyaluronan in human malignancies
- (2010) R.K. Sironen et al. EXPERIMENTAL CELL RESEARCH
- Hyaluronan Stabilizes Focal Adhesions, Filopodia, and the Proliferative Phenotype in Esophageal Squamous Carcinoma Cells
- (2010) Sören Twarock et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Expression of Hyaluronan Synthases (HAS1–3) and Hyaluronidases (HYAL1–2) in Serous Ovarian Carcinomas: Inverse Correlation between HYAL1 and Hyaluronan Content
- (2009) Timo K Nykopp et al. BMC CANCER
- Hyaluronan-CD44 Interactions in Cancer: Paradoxes and Possibilities
- (2009) B. P. Toole CLINICAL CANCER RESEARCH
- 4-Methylumbelliferone inhibits hyaluronan synthesis by depletion of cellular UDP-glucuronic acid and downregulation of hyaluronan synthase 2 and 3
- (2009) Anne Kultti et al. EXPERIMENTAL CELL RESEARCH
- Mannose Inhibits Hyaluronan Synthesis by Down-regulation of the Cellular Pool of UDP-N-acetylhexosamines
- (2008) Tiina A. Jokela et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Hyaluronan in Cancer Biology
- (2008) Robert Stern SEMINARS IN CANCER BIOLOGY
- Hyaluronan: A constitutive regulator of chemoresistance and malignancy in cancer cells
- (2008) Bryan P. Toole et al. SEMINARS IN CANCER BIOLOGY
- Hyaluronan in human tumors: Pathobiological and prognostic messages from cell-associated and stromal hyaluronan
- (2008) Raija H. Tammi et al. SEMINARS IN CANCER BIOLOGY
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started