Reduced replication fork speed promotes pancreatic endocrine differentiation and controls graft size

Acquisition of Dynamic Function in Human Stem Cell-Derived β Cells

(2019) Leonardo Velazco-Cruz et al.   Stem Cell Reports

A Double Fail-Safe Approach to Prevent Tumorigenesis and Select Pancreatic β Cells from Human Embryonic Stem Cells

(2019) Mirza Muhammad Fahd Qadir et al.   Stem Cell Reports

Recapitulating endocrine cell clustering in culture promotes maturation of human stem-cell-derived β cells

(2019) Gopika G. Nair et al.   NATURE CELL BIOLOGY

Charting cellular identity during human in vitro β-cell differentiation

(2019) Adrian Veres et al.   NATURE

g:Profiler: a web server for functional enrichment analysis and conversions of gene lists (2019 update)

(2019) Uku Raudvere et al.   NUCLEIC ACIDS RESEARCH

YAP inhibition enhances the differentiation of functional stem cell-derived insulin-producing β cells

(2019) Edwin A. Rosado-Olivieri et al.   Nature Communications

GNAS gene is an important regulator of insulin secretory capacity in pancreatic β-cells

(2019) Jalal Taneera et al.   GENE

Pseudotime Ordering of Single Human β-Cells Reveals States of Insulin Production and Unfolded Protein Response

(2018) Yurong Xin et al.   DIABETES

Replication confers β cell immaturity

(2018) Sapna Puri et al.   Nature Communications

GADD45A and CDKN1A are involved in apoptosis and cell cycle modulatory effects of viscumTT with further inactivation of the STAT3 pathway

(2018) Susann Kleinsimon et al.   Scientific Reports

β Cell Replacement after Gene Editing of a Neonatal Diabetes-Causing Mutation at the Insulin Locus

(2018) Shuangyu Ma et al.   Stem Cell Reports

DNA damage during S-phase mediates the proliferation-quiescence decision in the subsequent G1 via p21 expression

(2017) Alexis R. Barr et al.   Nature Communications

Endogenous Replication Stress in Mother Cells Leads to Quiescence of Daughter Cells

(2017) Mansi Arora et al.   Cell Reports

Long Neural Genes Harbor Recurrent DNA Break Clusters in Neural Stem/Progenitor Cells

(2016) Pei-Chi Wei et al.   CELL

Age-Dependent Pancreatic Gene Regulation Reveals Mechanisms Governing Human β Cell Function

(2016) H. Efsun Arda et al.   Cell Metabolism

Inhibition of Pluripotency Networks by the Rb Tumor Suppressor Restricts Reprogramming and Tumorigenesis

(2015) Michael S. Kareta et al.   Cell Stem Cell

Crosstalk between stem cell and cell cycle machineries

(2015) Michael S Kareta et al.   CURRENT OPINION IN CELL BIOLOGY

Human pancreas development

(2015) R. E. Jennings et al.   DEVELOPMENT

Generation of Functional Human Pancreatic β Cells In Vitro

(2014) Felicia W. Pagliuca et al.   CELL

Development of a conditionally immortalized human pancreatic β cell line

(2014) Raphaël Scharfmann et al.   JOURNAL OF CLINICAL INVESTIGATION

Reversal of diabetes with insulin-producing cells derived in vitro from human pluripotent stem cells

(2014) Alireza Rezania et al.   NATURE BIOTECHNOLOGY

Minocycline and cisplatin exert synergistic growth suppression on hepatocellular carcinoma by inducing S phase arrest and apoptosis

(2014) FU-YAO LIU et al.   ONCOLOGY REPORTS

Nervous decision-making: to divide or differentiate

(2014) Laura J.A. Hardwick et al.   TRENDS IN GENETICS

Human pluripotent stem cells: an emerging model in developmental biology

(2013) Z. Zhu et al.   DEVELOPMENT

Mosaic Copy Number Variation in Human Neurons

(2013) M. J. McConnell et al.   SCIENCE

Nkx6.1 Is Essential for Maintaining the Functional State of Pancreatic Beta Cells

(2013) Brandon L. Taylor et al.   Cell Reports

Stepwise Activation of the ATR Signaling Pathway upon Increasing Replication Stress Impacts Fragile Site Integrity

(2013) Stéphane Koundrioukoff et al.   PLoS Genetics

Prolonged early G1 arrest by selective CDK4/CDK6 inhibition sensitizes myeloma cells to cytotoxic killing through cell cycle-coupled loss of IRF4

(2012) X. Huang et al.   BLOOD

Human  -Cell Proliferation and Intracellular Signaling: Driving in the Dark Without a Road Map

(2012) R. N. Kulkarni et al.   DIABETES

High Passage MIN6 Cells Have Impaired Insulin Secretion with Impaired Glucose and Lipid Oxidation

(2012) Kim Cheng et al.   PLoS One

Convergence of the Insulin and Serotonin Programs in the Pancreatic  -Cell

(2011) Y. Ohta et al.   DIABETES

INS GFP/w human embryonic stem cells facilitate isolation of in vitro derived insulin-producing cells

(2011) S. J. Micallef et al.   DIABETOLOGIA

Replication stress induces 53BP1-containing OPT domains in G1 cells

(2011) Jeanine A. Harrigan et al.   JOURNAL OF CELL BIOLOGY

53BP1 nuclear bodies form around DNA lesions generated by mitotic transmission of chromosomes under replication stress

(2011) Claudia Lukas et al.   NATURE CELL BIOLOGY

Microfluidic perifusion and imaging device for multi-parametric islet function assessment

(2010) Adeola F. Adewola et al.   BIOMEDICAL MICRODEVICES

The Retinoblastoma Protein and Its Homolog p130 Regulate the G1/S Transition in Pancreatic  -Cells

(2009) G. Harb et al.   DIABETES

MIN6 Is Not a Pure Beta Cell Line but a Mixed Cell Line with Other Pancreatic Endocrine Hormones

(2009) Koji NAKASHIMA et al.   ENDOCRINE JOURNAL

Senescence impairs successful reprogramming to pluripotent stem cells

(2009) A. Banito et al.   GENES & DEVELOPMENT

Linking the p53 tumour suppressor pathway to somatic cell reprogramming

(2009) Teruhisa Kawamura et al.   NATURE

Cohesin acetylation speeds the replication fork

(2009) Marie-Emilie Terret et al.   NATURE

A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity

(2009) Rosa M. Marión et al.   NATURE

Suppression of induced pluripotent stem cell generation by the p53–p21 pathway

(2009) Hyenjong Hong et al.   NATURE

Immortalization eliminates a roadblock during cellular reprogramming into iPS cells

(2009) Jochen Utikal et al.   NATURE

The Ink4/Arf locus is a barrier for iPS cell reprogramming

(2009) Han Li et al.   NATURE

Lessons From the First Comprehensive Molecular Characterization of Cell Cycle Control in Rodent Insulinoma Cell Lines

(2008) I. Cozar-Castellano et al.   DIABETES

Microfluidic device for multimodal characterization of pancreatic islets

(2008) Javeed Shaikh Mohammed et al.   LAB ON A CHIP

Mediators of reprogramming: transcription factors and transitions through mitosis

(2008) Dieter Egli et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY