Rapamycin enhances BCG-specific γδ T cells during intravesical BCG therapy for non-muscle invasive bladder cancer: a randomized, double-blind study

Treatment of High-grade Non–muscle-invasive Bladder Carcinoma by Standard Number and Dose of BCG Instillations Versus Reduced Number and Standard Dose of BCG Instillations: Results of the European Association of Urology Research Foundation Randomised Phase III Clinical Trial “NIMBUS”

(2020) Marc-Oliver Grimm et al.   EUROPEAN UROLOGY

Percutaneous BCG enhances innate effector antitumor cytotoxicity during treatment of bladder cancer: a translational clinical trial

(2019) Niannian Ji et al.   OncoImmunology

Urine-derived lymphocytes as a non-invasive measure of the bladder tumor immune microenvironment

(2018) Yien Ning Sophia Wong et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Clinically-Relevant Rapamycin Treatment Regimens Enhance CD8+ Effector Memory T Cell Function In The Skin and Allow their Infiltration into Cutaneous Squamous Cell Carcinoma

(2018) Ji-Won Jung et al.   OncoImmunology

Intratumoral CD56bright natural killer cells are associated with improved survival in bladder cancer

(2018) Neelam Mukherjee et al.   Oncotarget

Prevention of everolimus-related stomatitis in women with hormone receptor-positive, HER2-negative metastatic breast cancer using dexamethasone mouthwash (SWISH): a single-arm, phase 2 trial

(2017) Hope S Rugo et al.   LANCET ONCOLOGY

Immune-Stimulatory Effects of Rapamycin Are Mediated by Stimulation of Antitumor    T Cells

(2016) V. Dao et al.   CANCER RESEARCH

mTOR inhibition potentiates cytotoxicity of Vγ4 γδ T cells via up-regulating NKG2D and TNF-α

(2016) Guangchao Cao et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Intermittent Administration of Rapamycin Extends the Life Span of Female C57BL/6J Mice

(2016) Sebastian I. Arriola Apelo et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Modulation of mTOR Signalling Triggers the Formation of Stem Cell-like Memory T Cells

(2016) Godehard Scholz et al.   EBioMedicine

Alternative rapamycin treatment regimens mitigate the impact of rapamycin on glucose homeostasis and the immune system

(2015) Sebastian I. Arriola Apelo et al.   AGING CELL

Friends Not Foes: CTLA-4 Blockade and mTOR Inhibition Cooperate during CD8+T Cell Priming To Promote Memory Formation and Metabolic Readiness

(2015) Virginia A. Pedicord et al.   JOURNAL OF IMMUNOLOGY

Lifespan extension and cancer prevention in HER-2/neu transgenic mice treated with low intermittent doses of rapamycin

(2014) Irina G Popovich et al.   CANCER BIOLOGY & THERAPY

Sequential Intravesical Mitomycin plus Bacillus Calmette-Guerin for Non-Muscle-Invasive Urothelial Bladder Carcinoma: Translational and Phase I Clinical Trial

(2014) R. S. Svatek et al.   CLINICAL CANCER RESEARCH

mTOR inhibition improves immune function in the elderly

(2014) J. B. Mannick et al.   Science Translational Medicine

Preexisting BCG-Specific T Cells Improve Intravesical Immunotherapy for Bladder Cancer

(2012) C. Biot et al.   Science Translational Medicine

Human    T lymphocytes induce robust NK cell-mediated antitumor cytotoxicity through CD137 engagement

(2010) A. Maniar et al.   BLOOD

Rapamycin increases the yield and effector function of human γδ T cells stimulated in vitro

(2010) Haishan Li et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

IL-17 production by γδ T cells is important for the antitumor effect of Mycobacterium bovis bacillus Calmette-Guérin treatment against bladder cancer

(2010) Ario Takeuchi et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Molecular Analyte Profiling of the Early Events and Tissue Conditioning Following Intravesical Bacillus Calmette-Guerin Therapy in Patients With Superficial Bladder Cancer

(2009) Aurélie Bisiaux et al.   JOURNAL OF UROLOGY

mTOR regulates memory CD8 T-cell differentiation

(2009) Koichi Araki et al.   NATURE

Autophagy enhances the efficacy of BCG vaccine by increasing peptide presentation in mouse dendritic cells

(2009) Chinnaswamy Jagannath et al.   NATURE MEDICINE

Design of aging intervention studies: the NIA interventions testing program

(2008) N. L. Nadon et al.   AGE

A New Recombinant Bacille Calmette‐Guérin Vaccine Safely Induces Significantly Enhanced Tuberculosis‐Specific Immunity in Human Volunteers

(2008) Daniel F. Hoft et al.   JOURNAL OF INFECTIOUS DISEASES