Metformin enhances anti-cancer effects of cisplatin in meningioma through AMPK-mTOR signaling pathways
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Metformin enhances anti-cancer effects of cisplatin in meningioma through AMPK-mTOR signaling pathways
Authors
Keywords
meningioma, metformin, cisplatin, AMPK, mTOR
Journal
Molecular Therapy-Oncolytics
Volume 20, Issue -, Pages 119-131
Publisher
Elsevier BV
Online
2020-11-21
DOI
10.1016/j.omto.2020.11.004
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Metformin induces human esophageal carcinoma cell pyroptosis by targeting the miR-497/PELP1 axis
- (2019) Lu Wang et al. CANCER LETTERS
- Ginsenoside Rb3 provides protective effects against cisplatin‐induced nephrotoxicity via regulation of AMPK‐/mTOR‐mediated autophagy and inhibition of apoptosis in vitro and in vivo
- (2019) Jing‐jing Xing et al. CELL PROLIFERATION
- Metformin attenuates cisplatin-induced genotoxicity and apoptosis in rat bone marrow cells
- (2019) Mohsen Cheki et al. DRUG AND CHEMICAL TOXICOLOGY
- Cisplatin: The first metal based anticancer drug
- (2019) Sumit Ghosh BIOORGANIC CHEMISTRY
- Metformin-induced AMPK activation stimulates remyelination through induction of neurotrophic factors, downregulation of NogoA and recruitment of Olig2+ precursor cells in the cuprizone murine model of multiple sclerosis
- (2019) Fariba Houshmand et al. DARU-Journal of Pharmaceutical Sciences
- Metformin and FTY720 Synergistically Induce Apoptosis in Multiple Myeloma Cells
- (2018) Yi Zhao et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Current treatment options for meningioma
- (2018) Caroline Apra et al. Expert Review of Neurotherapeutics
- Metformin induces autophagy and G0/G1 phase cell cycle arrest in myeloma by targeting the AMPK/mTORC1 and mTORC2 pathways
- (2018) Yan Wang et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Metformin enhances cisplatin induced inhibition of cholangiocarcinoma cells via AMPK-mTOR pathway
- (2018) Jaroon Wandee et al. LIFE SCIENCES
- Current treatment options for meningioma
- (2018) Caroline Apra et al. Expert Review of Neurotherapeutics
- Metformin Enhances Cisplatin-Induced Apoptosis and Prevents Resistance to Cisplatin in Co-mutated KRAS/LKB1 NSCLC
- (2018) Massimo Moro et al. Journal of Thoracic Oncology
- Metformin as an Anticancer Agent
- (2018) Ales Vancura et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Metformin increases sensitivity of osteosarcoma stem cells to cisplatin by inhibiting expression of PKM2
- (2017) Depeng Shang et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Loss of AMPK activation promotes the invasion and metastasis of pancreatic cancer through an HSF1-dependent pathway
- (2017) Ke Chen et al. Molecular Oncology
- The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary
- (2016) David N. Louis et al. ACTA NEUROPATHOLOGICA
- Metformin potentiates the anticancer activities of gemcitabine and cisplatin against cholangiocarcinoma cells in vitro and in vivo
- (2016) Hua-Qiang Zhu et al. ONCOLOGY REPORTS
- Metformin Protects Against Cisplatin-Induced Tubular Cell Apoptosis and Acute Kidney Injury via AMPKα-regulated Autophagy Induction
- (2016) Jianzhong Li et al. Scientific Reports
- Repurposing metformin: an old drug with new tricks in its binding pockets
- (2015) R. Pryor et al. BIOCHEMICAL JOURNAL
- A phase I dose-escalation study to assess safety, tolerability, pharmacokinetics, and preliminary efficacy of the dual mTORC1/mTORC2 kinase inhibitor CC-223 in patients with advanced solid tumors or multiple myeloma
- (2015) Johanna C. Bendell et al. CANCER
- Combined therapeutic effect and molecular mechanisms of metformin and cisplatin in human lung cancer xenografts in nude mice
- (2015) Gang Chen et al. Journal of Cancer Research and Therapeutics
- An evidence-based treatment algorithm for the management of WHO Grade II and III meningiomas
- (2015) Sam Q. Sun et al. Neurosurgical Focus
- Metformin potentiates rapamycin and cisplatin in gastric cancer in mice
- (2015) Guanzhen Yu et al. Oncotarget
- Reduced Risk of Lung Cancer With Metformin Therapy in Diabetic Patients: A Systematic Review and Meta-Analysis
- (2014) Zhi-Jiang Zhang et al. AMERICAN JOURNAL OF EPIDEMIOLOGY
- Rictor/mTORC2 protects against cisplatin-induced tubular cell death and acute kidney injury
- (2014) Jianzhong Li et al. KIDNEY INTERNATIONAL
- Metformin—mode of action and clinical implications for diabetes and cancer
- (2014) Ida Pernicova et al. Nature Reviews Endocrinology
- Historical benchmarks for medical therapy trials in surgery- and radiation-refractory meningioma: a RANO review
- (2014) T. Kaley et al. NEURO-ONCOLOGY
- The Anti-Diabetic Drug Metformin Protects against Chemotherapy-Induced Peripheral Neuropathy in a Mouse Model
- (2014) Qi-Liang Mao-Ying et al. PLoS One
- Prognostic Significance of AMPK Activation and Therapeutic Effects of Metformin in Hepatocellular Carcinoma
- (2013) L. Zheng et al. CLINICAL CANCER RESEARCH
- AMP-activated protein kinase mediates activity-dependent axon branching by recruiting mitochondria to axon
- (2013) Kentaro Tao et al. Developmental Neurobiology
- AMPK activation regulates neuronal structure in developing hippocampal neurons
- (2013) S. Ramamurthy et al. NEUROSCIENCE
- Recent developments in chemotherapy for meningiomas: a review
- (2013) Alan A. Moazzam et al. Neurosurgical Focus
- Repositioning metformin for cancer prevention and treatment
- (2013) Brendan J. Quinn et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- AMPK interacts with DSCAM and plays an important role in Netrin-1 induced neurite outgrowth
- (2013) Kun Zhu et al. Protein & Cell
- mTOR Signaling in Growth Control and Disease
- (2012) Mathieu Laplante et al. CELL
- Therapeutic metformin/AMPK activation blocked lymphoma cell growth via inhibition of mTOR pathway and induction of autophagy
- (2012) W-Y Shi et al. Cell Death & Disease
- The impact of phosphorylated AMP-activated protein kinase expression on lung cancer survival
- (2011) W. N. William et al. ANNALS OF ONCOLOGY
- Type 2 diabetes increases and metformin reduces total, colorectal, liver and pancreatic cancer incidences in Taiwanese: a representative population prospective cohort study of 800,000 individuals
- (2011) Meei-Shyuan Lee et al. BMC CANCER
- Metformin inhibits breast cancer cell growth, colony formation and induces cell cycle arrest in vitro
- (2011) Irina N. Alimova et al. CELL CYCLE
- The AMPK signalling pathway coordinates cell growth, autophagy and metabolism
- (2011) Maria M. Mihaylova et al. NATURE CELL BIOLOGY
- Long-Term Metformin Use Is Associated With Decreased Risk of Breast Cancer
- (2010) M. Bodmer et al. DIABETES CARE
- Tumor suppressors and cell metabolism: a recipe for cancer growth
- (2009) R. G. Jones et al. GENES & DEVELOPMENT
- Expression of survivin and p16INK4a/Cdk6/pRB proteins and induction of apoptosis in response to radiation and cisplatin in meningioma cells
- (2007) Huda H. Al-Khalaf et al. BRAIN RESEARCH
- Dose translation from animal to human studies revisited
- (2007) Shannon Reagan-Shaw et al. FASEB JOURNAL
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search