Metformin attenuates cisplatin-induced genotoxicity and apoptosis in rat bone marrow cells

Metformin: Prevention of genomic instability and cancer: A review

(2018) Masoud Najafi et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Metformin: a review of its potential indications

(2017) Yi-Wei Wang et al.   Drug Design Development and Therapy

Metformin improves defective hematopoiesis and delays tumor formation in Fanconi anemia mice

(2016) Q.-S. Zhang et al.   BLOOD

An oxovanadium(IV) complex protects murine bone marrow cells against cisplatin-induced myelotoxicity and DNA damage

(2016) Abhishek Basu et al.   DRUG AND CHEMICAL TOXICOLOGY

The radioprotective effect of metformin against cytotoxicity and genotoxicity induced by ionizing radiation in cultured human blood lymphocytes

(2016) Mohsen Cheki et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Metformin potentiates the anticancer activities of gemcitabine and cisplatin against cholangiocarcinoma cells in vitro and in vivo

(2016) Hua-Qiang Zhu et al.   ONCOLOGY REPORTS

Metformin Attenuates131I-Induced Decrease in Peripheral Blood Cells in Patients with Differentiated Thyroid Cancer

(2016) Athanasios Bikas et al.   THYROID

Metformin sensitizes the response of oral squamous cell carcinoma to cisplatin treatment through inhibition of NF-κB/HIF-1α signal axis

(2016) Xiaofeng Qi et al.   Scientific Reports

Metformin Prevents Cisplatin-Induced Cognitive Impairment and Brain Damage in Mice

(2016) Wenjun Zhou et al.   PLoS One

Metformin Protects Against Cisplatin-Induced Tubular Cell Apoptosis and Acute Kidney Injury via AMPKα-regulated Autophagy Induction

(2016) Jianzhong Li et al.   Scientific Reports

Glutathione selectively modulates the binding of platinum drugs to human copper chaperone Cox17

(2015) L. Zhao et al.   BIOCHEMICAL JOURNAL

Metformin ameliorates ionizing irradiation-induced long-term hematopoietic stem cell injury in mice

(2015) Guoshun Xu et al.   FREE RADICAL BIOLOGY AND MEDICINE

In vitro and in vivo targeting of bladder carcinoma with metformin in combination with cisplatin

(2015) DONG WANG et al.   Oncology Letters

Squalene Selectively Protects Mouse Bone Marrow Progenitors Against Cisplatin and Carboplatin-Induced Cytotoxicity In Vivo Without Protecting Tumor Growth

(2015) Bikul Das et al.   NEOPLASIA

Metformin synergistically enhances antiproliferative effects of cisplatin and etoposide in NCI-H460 human lung cancer cells

(2014) Sarah Fernandes Teixeira et al.   Jornal Brasileiro de Pneumologia

Protective Effects of Common Anthocyanidins against Genotoxic Damage Induced by Chemotherapeutic Drugs in Mice

(2014) Nidhi Khandelwal et al.   PLANTA MEDICA

The Anti-Diabetic Drug Metformin Protects against Chemotherapy-Induced Peripheral Neuropathy in a Mouse Model

(2014) Qi-Liang Mao-Ying et al.   PLoS One

Metformin Enhances Cisplatin Cytotoxicity by Suppressing Signal Transducer and Activator of Transcription–3 Activity Independently of the Liver Kinase B1–AMP-Activated Protein Kinase Pathway

(2013) Chien-Chung Lin et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Metformin and cancer

(2013) Christos V. Rizos et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Effect of metformin against cisplatin induced acute renal injury in rats: A biochemical and histoarchitectural evaluation

(2013) Bidya Dhar Sahu et al.   EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY

Metformin's performance in in vitro and in vivo genetic toxicology studies

(2013) Juliane R Sant'Anna et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Protective Effect of Metformin Against Cisplatin-Induced Ototoxicity in an Auditory Cell Line

(2013) Jiwon Chang et al.   JARO-JOURNAL OF THE ASSOCIATION FOR RESEARCH IN OTOLARYNGOLOGY

Neuroprotection with metformin and thymoquinone against ethanol-induced apoptotic neurodegeneration in prenatal rat cortical neurons

(2012) Ikram Ullah et al.   BMC NEUROSCIENCE

Metformin Reduces Endogenous Reactive Oxygen Species and Associated DNA Damage

(2012) C. Algire et al.   Cancer Prevention Research

Induction of DNA fragmentation, chromosome aberrations and micronuclei by cisplatin in rat bone-marrow cells: Protective effect of recombinant human erythropoietin

(2012) Karima Rjiba-Touati et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Cellular and molecular mechanisms of metformin: an overview

(2011) Benoit Viollet et al.   CLINICAL SCIENCE

Metformin protects against doxorubicin-induced cardiotoxicity: Involvement of the adiponectin cardiac system

(2011) Mari C. Asensio-López et al.   FREE RADICAL BIOLOGY AND MEDICINE

Influence of resveratrol on oxidative damage in genomic DNA and apoptosis induced by cisplatin

(2011) Sabry M. Attia   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Lutein improves antioxidant defense in vivo and protects against DNA damage and chromosome instability induced by cisplatin

(2010) Juliana Mara Serpeloni et al.   ARCHIVES OF TOXICOLOGY

Metformin reduces intracellular reactive oxygen species levels by upregulating expression of the antioxidant thioredoxin via the AMPK-FOXO3 pathway

(2010) Xinguo Hou et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The relationship between cisplatin-induced reactive oxygen species, glutathione, and BCL-2 and resistance to cisplatin

(2010) Anamaria Brozovic et al.   CRITICAL REVIEWS IN TOXICOLOGY

Metformin prevents experimental gentamicin-induced nephropathy by a mitochondria-dependent pathway

(2010) Ana I. Morales et al.   KIDNEY INTERNATIONAL

The impact of quercetin on cisplatin-induced clastogenesis and apoptosis in murine marrow cells

(2010) S. M. Attia   MUTAGENESIS

Assessment of genomic instability in normal and diabetic rats treated with metformin

(2009) S.M. Attia et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Anticlastogenic effect of caffeic acid phenethyl ester on cisplatin-induced chromosome aberrations in rat bone marrow cells

(2009) H. Ramazan Yılmaz et al.   TOXICOLOGY AND INDUSTRIAL HEALTH

Bixin and lycopene modulation of free radical generation induced by cisplatin–DNA interaction

(2008) Alessandro de O. Rios et al.   FOOD CHEMISTRY

Dose translation from animal to human studies revisited

(2007) Shannon Reagan-Shaw et al.   FASEB JOURNAL