RRM2B Is Frequently Amplified Across Multiple Tumor Types: Implications for DNA Repair, Cellular Survival, and Cancer Therapy
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Title
RRM2B Is Frequently Amplified Across Multiple Tumor Types: Implications for DNA Repair, Cellular Survival, and Cancer Therapy
Authors
Keywords
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Journal
Frontiers in Genetics
Volume 12, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2021-03-12
DOI
10.3389/fgene.2021.628758
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Note: Only part of the references are listed.- The repertoire of mutational signatures in human cancer
- (2020) Ludmil B. Alexandrov et al. NATURE
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- (2019) Sara Ballabio et al. INTERNATIONAL JOURNAL OF CANCER
- WebGestalt 2019: gene set analysis toolkit with revamped UIs and APIs
- (2019) Yuxing Liao et al. NUCLEIC ACIDS RESEARCH
- Advances in therapeutic targeting of the DNA damage response in cancer
- (2018) Amar Desai et al. DNA REPAIR
- Challenges to DNA replication in hypoxic conditions
- (2018) Natalie Ng et al. FEBS Journal
- Copy number signatures and mutational processes in ovarian carcinoma
- (2018) Geoff Macintyre et al. NATURE GENETICS
- The therapeutic significance of mutational signatures from DNA repair deficiency in cancer
- (2018) Jennifer Ma et al. Nature Communications
- The BioGRID interaction database: 2019 update
- (2018) Rose Oughtred et al. NUCLEIC ACIDS RESEARCH
- Drugging the Cancers Addicted to DNA Repair
- (2017) Jac A. Nickoloff et al. JNCI-Journal of the National Cancer Institute
- Ribonucleotide Reductase Requires Subunit Switching in Hypoxia to Maintain DNA Replication
- (2017) Iosifina P. Foskolou et al. MOLECULAR CELL
- Phenotypic and Genotypic Heterogeneity of RRM2B Variants
- (2017) Sinda Zarrouk-Mahjoub et al. NEUROPEDIATRICS
- Genes co-amplified with ERBB2 or MET as novel potential cancer-promoting genes in gastric cancer
- (2017) Mi Jeong Kwon et al. Oncotarget
- Drugging the Cancers Addicted to DNA Repair
- (2017) Jac A. Nickoloff et al. JNCI-Journal of the National Cancer Institute
- MYC Deregulation in Primary Human Cancers
- (2017) Manpreet Kalkat et al. Genes
- Whole-exome sequencing of Finnish hereditary breast cancer families
- (2016) Kirsi Määttä et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- TP53Mutations in Head and Neck Squamous Cell Carcinoma and Their Impact on Disease Progression and Treatment Response
- (2016) Ge Zhou et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Genomic landscape of DNA repair genes in cancer
- (2016) Young Kwang Chae et al. Oncotarget
- Multifaceted control of DNA repair pathways by the hypoxic tumor microenvironment
- (2015) Susan E. Scanlon et al. DNA REPAIR
- Caspase-dependent Proteolysis of Human Ribonucleotide Reductase Small Subunits R2 and p53R2 during Apoptosis
- (2015) Ali Tebbi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Targeting the DNA Damage Response in Cancer
- (2015) Mark J. O’Connor MOLECULAR CELL
- Tumor suppressor FOXO3 regulates ribonucleotide reductase subunit RRM2B and impacts on survival of cancer patients
- (2015) Er-Chieh Cho et al. Oncotarget
- E2F1 regulates p53R2 gene expression in p53-deficient cells
- (2014) Jun-Juan Qi et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Ribonucleotide reductase and cancer: biological mechanisms and targeted therapies
- (2014) Y Aye et al. ONCOGENE
- Genetic Alterations of Chromosome 8 Genes in Oral Cancer
- (2014) Zachary Wei Ern Yong et al. Scientific Reports
- Frequent MYC coamplification and DNA hypomethylation of multiple genes on 8q in 8p11-p12-amplified breast carcinomas
- (2014) T Z Parris et al. Oncogenesis
- DNA Base Damage by Reactive Oxygen Species, Oxidizing Agents, and UV Radiation
- (2013) J. Cadet et al. Cold Spring Harbor Perspectives in Biology
- INT6/EIF3E Interacts with ATM and Is Required for Proper Execution of the DNA Damage Response in Human Cells
- (2012) C. Morris et al. CANCER RESEARCH
- MEK2 regulates ribonucleotide reductase activity through functional interaction with ribonucleotide reductase small subunit p53R2
- (2012) Chunmei Piao et al. CELL CYCLE
- Amplified Loci on Chromosomes 8 and 17 Predict Early Relapse in ER-Positive Breast Cancers
- (2012) Erhan Bilal et al. PLoS One
- The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data: Figure 1.
- (2012) Ethan Cerami et al. Cancer Discovery
- RRM2B Suppresses Activation of the Oxidative Stress Pathway and is Up-regulated by P53 During Senescence
- (2012) Mei-Ling Kuo et al. Scientific Reports
- Ribonucleotide reductase subunit p53R2 regulates mitochondria homeostasis and function in KB and PC-3 cancer cells
- (2011) Xiaochen Wang et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Ribonucleotide Reductase Small Subunit M2B Prognoses Better Survival in Colorectal Cancer
- (2011) X. Liu et al. CANCER RESEARCH
- Finding consistent patterns: A nonparametric approach for identifying differential expression in RNA-Seq data
- (2011) Jun Li et al. STATISTICAL METHODS IN MEDICAL RESEARCH
- Targeting Hypoxic Cells through the DNA Damage Response
- (2010) M. Olcina et al. CLINICAL CANCER RESEARCH
- Mitochondrial Neurogastrointestinal Encephalopathy Due to Mutations in RRM2B
- (2009) Aziz Shaibani et al. ARCHIVES OF NEUROLOGY
- 2.6 Å X-ray Crystal Structure of Human p53R2, a p53-Inducible Ribonucleotide Reductase,
- (2009) Peter Smith et al. BIOCHEMISTRY
- Broad Overexpression of Ribonucleotide Reductase Genes in Mice Specifically Induces Lung Neoplasms
- (2008) X. Xu et al. CANCER RESEARCH
- Applying Hodges-Lehmann scale parameter estimates to hospital discharge times
- (2008) Jonathan J Shuster et al. Clinical Trials
- Mitochondrial DNA depletion syndrome due to mutations in the RRM2B gene
- (2008) Belén Bornstein et al. NEUROMUSCULAR DISORDERS
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