Single-Cell RNA Sequencing Reveals the Expansion of Cytotoxic CD4+ T Lymphocytes and a Landscape of Immune Cells in Primary Sjögren’s Syndrome

Cytotoxic CD4+ T lymphocytes may induce endothelial cell apoptosis in systemic sclerosis

(2020) Takashi Maehara et al.   JOURNAL OF CLINICAL INVESTIGATION

T cells in primary Sjögren’s syndrome: targets for early intervention

(2019) Gwenny M Verstappen et al.   RHEUMATOLOGY

Characteristics of dry eye in patients with pre-existing Sjögrenʼs syndrome according to the revised 2016 ACR-EULAR classification criteria

(2019) Hyeon Jeong Yoon et al.   MEDICINE

Defining inflammatory cell states in rheumatoid arthritis joint synovial tissues by integrating single-cell transcriptomics and mass cytometry

(2019) Fan Zhang et al.   NATURE IMMUNOLOGY

Tubular cell and keratinocyte single-cell transcriptomics applied to lupus nephritis reveal type I IFN and fibrosis relevant pathways

(2019) Evan Der et al.   NATURE IMMUNOLOGY

TMEM176A and TMEM176B are candidate regulators of inhibition of dendritic cell maturation and function after chronic spinal cord injury

(2019) Gabriela Picotto et al.   JOURNAL OF NEUROTRAUMA

The immune cell landscape in kidneys of patients with lupus nephritis

(2019) Arnon Arazi et al.   NATURE IMMUNOLOGY

Single-cell transcriptomics of human T cells reveals tissue and activation signatures in health and disease

(2019) Peter A. Szabo et al.   Nature Communications

Germline genetic patterns underlying familial rheumatoid arthritis, systemic lupus erythematosus and primary Sjögren’s syndrome highlight T cell-initiated autoimmunity

(2019) Yukai Wang et al.   ANNALS OF THE RHEUMATIC DISEASES

Current views on the pathogenesis of Sjögrenʼs syndrome

(2018) Elena Pontarini et al.   CURRENT OPINION IN RHEUMATOLOGY

Th17 cells in primary Sjögren's syndrome: Pathogenicity and plasticity

(2018) Gwenny M. Verstappen et al.   JOURNAL OF AUTOIMMUNITY

Tracing the temporal-spatial transcriptome landscapes of the human fetal digestive tract using single-cell RNA-sequencing

(2018) Shuai Gao et al.   NATURE CELL BIOLOGY

B cells in the pathogenesis of primary Sjögren syndrome

(2018) Gaëtane Nocturne et al.   Nature Reviews Rheumatology

Primary Sjögren’s Syndrome

(2018)   NEW ENGLAND JOURNAL OF MEDICINE

dropClust: efficient clustering of ultra-large scRNA-seq data

(2018) Debajyoti Sinha et al.   NUCLEIC ACIDS RESEARCH

Genomic Comparison Among Global Isolates of L. interrogans Serovars Copenhageni and Icterohaemorrhagiae Identified Natural Genetic Variation Caused by an Indel

(2018) Luciane A. Santos et al.   Frontiers in Cellular and Infection Microbiology

Clinical and immunological parameters of Sjögren's syndrome

(2018) Konstantia Psianou et al.   AUTOIMMUNITY REVIEWS

IL-2 Inhibition of Th17 Generation Rather Than Induction of Treg Cells Is Impaired in Primary Sjögren’s Syndrome Patients

(2018) Jing Luo et al.   Frontiers in Immunology

T-Cell Leukemia/Lymphoma 1 (TCL1): An Oncogene Regulating Multiple Signaling Pathways

(2018) Francesco Paduano et al.   Frontiers in Oncology

Estimation of immune cell content in tumour tissue using single-cell RNA-seq data

(2017) Max Schelker et al.   Nature Communications

Cytometry by time-of-flight immunophenotyping identifies a blood Sjögren's signature correlating with disease activity and glandular inflammation

(2016) Michael Mingueneau et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Clonal expansion of CD4 + cytotoxic T lymphocytes in patients with IgG 4 -related disease

(2016) Hamid Mattoo et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

A multicentre study of 95 biopsy-proven cases of renal disease in primary Sjögren’s syndrome

(2016) Magali Jasiek et al.   RHEUMATOLOGY

Cytomegalovirus Infection Leads to Development of High Frequencies of Cytotoxic Virus-Specific CD4+ T Cells Targeted to Vascular Endothelium

(2016) Annette Pachnio et al.   PLoS Pathogens

Identification of cell types from single-cell transcriptomes using a novel clustering method

(2015) Chen Xu et al.   BIOINFORMATICS

Data-Driven Phenotypic Dissection of AML Reveals Progenitor-like Cells that Correlate with Prognosis

(2015) Jacob H. Levine et al.   CELL

Genetic Basis for Clinical Response to CTLA-4 Blockade in Melanoma

(2015) Timothy A. Chan et al.   NEW ENGLAND JOURNAL OF MEDICINE

Epidemiology of primary Sjögren's syndrome: a systematic review and meta-analysis

(2014) Baodong Qin et al.   ANNALS OF THE RHEUMATIC DISEASES

Sjögren Syndrome-associated lymphomas: an update on pathogenesis and management

(2014) Gaetane Nocturne et al.   BRITISH JOURNAL OF HAEMATOLOGY

Role of Fractalkine in the Pathogenesis of Primary Sjogren Syndrome: Increased Serum Levels of Fractalkine, Its Expression in Labial Salivary Glands, and the Association with Clinical Manifestations

(2014) J. H. Lee et al.   JOURNAL OF RHEUMATOLOGY

Assessment of intracellular cytokines and regulatory cells in patients with autoimmune diseases and primary immunodeficiencies — Novel tool for diagnostics and patient follow-up

(2013) Liv T. Osnes et al.   AUTOIMMUNITY REVIEWS

Immunopathogenic mechanisms of systemic autoimmune disease

(2013) Marie Wahren-Herlenius et al.   LANCET

A genome-wide association study in Han Chinese identifies a susceptibility locus for primary Sjögren's syndrome at 7q11.23

(2013) Yongzhe Li et al.   NATURE GENETICS

Advances in understanding the pathogenesis of primary Sjögren's syndrome

(2013) Gaëtane Nocturne et al.   Nature Reviews Rheumatology

Peripheral and Site-Specific CD4+CD28nullT Cells from Rheumatoid Arthritis Patients Show Distinct Characteristics

(2013) J. Pieper et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Type I interferons in Sjögren's syndrome

(2012) Yihong Yao et al.   AUTOIMMUNITY REVIEWS

Data exploration, quality control and testing in single-cell qPCR-based gene expression experiments

(2012) Andrew McDavid et al.   BIOINFORMATICS

Selective localization of T helper subsets in labial salivary glands from primary Sjögren's syndrome patients

(2012) T. Maehara et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

CD4+CD28− T cell expansion in granulomatosis with polyangiitis (Wegener's) is driven by latent cytomegalovirus infection and is associated with an increased risk of infection and mortality

(2011) Matthew D. Morgan et al.   ARTHRITIS AND RHEUMATISM

Association of anticytomegalovirus seropositivity with more severe joint destruction and more frequent joint surgery in rheumatoid arthritis

(2011) Matthias Pierer et al.   ARTHRITIS AND RHEUMATISM

CX3CR1 drives cytotoxic CD4+CD28− T cells into the brain of multiple sclerosis patients

(2011) Bieke Broux et al.   JOURNAL OF AUTOIMMUNITY

Unfolding communities in large complex networks: Combining defensive and offensive label propagation for core extraction

(2011) Lovro Šubelj et al.   PHYSICAL REVIEW E

Anti-5S RNA/protein (RNP) antibody levels correlate with disease activity in a patient with systemic lupus erythematosus (SLE) nephritis

(2010) A. GUIALIS et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Expression of dendritic cell markers CD11c/BDCA-1 and CD123/BDCA-2 in coronary artery disease upon activation in whole blood

(2010) Ilse Van Brussel et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Salivary chemokine levels in patients with primary Sjogren's syndrome

(2010) Y. J. Lee et al.   RHEUMATOLOGY

TCL1A expression delineates biological and clinical variability in B-cell lymphoma

(2008) Mohit Aggarwal et al.   MODERN PATHOLOGY