Interactions of the Skin Pathogen Haemophilus ducreyi With the Human Host

Spatial metabolomics of in situ host–microbe interactions at the micrometre scale

(2020) Benedikt Geier et al.   Nature Microbiology

Buruli ulcer: The Efficacy of Innate Immune Defense May Be a Key Determinant for the Outcome of Infection With Mycobacterium ulcerans

(2020) Katharina Röltgen et al.   Frontiers in Microbiology

Dual RNA-Seq of Human Leprosy Lesions Identifies Bacterial Determinants Linked to Host Immune Response

(2019) Dennis J. Montoya et al.   Cell Reports

A class I Haemophilus ducreyi strain containing a class II hgbA allele is partially attenuated in humans: implications for HgbA vaccine efficacy trials

(2019) Isabelle Leduc et al.   INFECTION AND IMMUNITY

Comprehensive Integration of Single-Cell Data

(2019) Tim Stuart et al.   CELL

Determination of an Interaction Network between an Extracellular Bacterial Pathogen and the Human Host

(2019) Brad Griesenauer et al.   mBio

Interaction with the host: the role of fibronectin and extracellular matrix proteins in the adhesion of Gram-negative bacteria

(2019) Diana J. Vaca et al.   MEDICAL MICROBIOLOGY AND IMMUNOLOGY

Multiple Class I and Class II Haemophilus ducreyi Strains Cause Cutaneous Ulcers in Children on an Endemic Island

(2018) Jacob C Grant et al.   CLINICAL INFECTIOUS DISEASES

Role of Human Macrophage Polarization in Inflammation during Infectious Diseases

(2018) Chiraz Atri et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Re-emergence of yaws after single mass azithromycin treatment followed by targeted treatment: a longitudinal study

(2018) Oriol Mitjà et al.   LANCET

Innate Immune Responses in Leprosy

(2018) Roberta Olmo Pinheiro et al.   Frontiers in Immunology

Metabolic Modulation in Macrophage Effector Function

(2018) Ciana Diskin et al.   Frontiers in Immunology

Transcriptional Programming of Normal and Inflamed Human Epidermis at Single-Cell Resolution

(2018) Jeffrey B. Cheng et al.   Cell Reports

Mycobacterium leprae Recombinant Antigen Induces High Expression of Multifunction T Lymphocytes and Is Promising as a Specific Vaccine for Leprosy

(2018) Márcio Bezerra-Santos et al.   Frontiers in Immunology

CD49a Expression Defines Tissue-Resident CD8 + T Cells Poised for Cytotoxic Function in Human Skin

(2017) Stanley Cheuk et al.   IMMUNITY

Haemophilus ducreyi DNA is detectable on the skin of asymptomatic children, flies and fomites in villages of Papua New Guinea

(2017) Wendy Houinei et al.   PLoS Neglected Tropical Diseases

Leprosy As a Complex Infection: Breakdown of the Th1 and Th2 Immune Paradigm in the Immunopathogenesis of the Disease

(2017) Jorge Rodrigues de Sousa et al.   Frontiers in Immunology

Haemophilus ducreyi Seeks Alternative Carbon Sources and Adapts to Nutrient Stress and Anaerobiosis during Experimental Infection of Human Volunteers

(2016) Dharanesh Gangaiah et al.   INFECTION AND IMMUNITY

Host Polymorphisms inTLR9andIL10Are Associated With the Outcomes of ExperimentalHaemophilus ducreyiInfection in Human Volunteers

(2016) Martin Singer et al.   JOURNAL OF INFECTIOUS DISEASES

Haemophilus ducreyi Cutaneous Ulcer Strains Diverged from Both Class I and Class II Genital Ulcer Strains: Implications for Epidemiological Studies

(2016) Dharanesh Gangaiah et al.   PLoS Neglected Tropical Diseases

DksA and (p)ppGpp Have Unique and Overlapping Contributions to Haemophilus ducreyi Pathogenesis in Humans

(2015) Concerta L. Holley et al.   INFECTION AND IMMUNITY

Adaptive Immunity againstStreptococcus pyogenesin Adults Involves Increased IFN-γ and IgG3 Responses Compared with Children

(2015) Rasmus Mortensen et al.   JOURNAL OF IMMUNOLOGY

The Human Skin Microbiome Associates with the Outcome of and Is Influenced by Bacterial Infection

(2015) Julia J. van Rensburg et al.   mBio

Haemophilus ducreyi Cutaneous Ulcer Strains Are Nearly Identical to Class I Genital Ulcer Strains

(2015) Dharanesh Gangaiah et al.   PLoS Neglected Tropical Diseases

A Cross-Sectional Study of ‘Yaws’ in Districts of Ghana Which Have Previously Undertaken Azithromycin Mass Drug Administration for Trachoma Control

(2015) Rosanna Ghinai et al.   PLoS Neglected Tropical Diseases

Memory Th1 Cells Are Protective in Invasive Staphylococcus aureus Infection

(2015) Aisling F. Brown et al.   PLoS Pathogens

Phosphoethanolamine Transferase LptA in Haemophilus ducreyi Modifies Lipid A and Contributes to Human Defensin Resistance In Vitro

(2015) Michael P. Trombley et al.   PLoS One

Outer membrane protein P4 is not required for virulence in the human challenge model of Haemophilus ducreyi infection

(2014) Diane M Janowicz et al.   BMC MICROBIOLOGY

A (p)ppGpp-Null Mutant of Haemophilus ducreyi Is Partially Attenuated in Humans Due to Multiple Conflicting Phenotypes

(2014) Concerta Holley et al.   INFECTION AND IMMUNITY

Toxic Interaction between Th2 Cytokines and Staphylococcus aureus in Atopic Dermatitis

(2014) Jeffrey B. Travers   JOURNAL OF INVESTIGATIVE DERMATOLOGY

The Haemophilus ducreyi trimeric autotransporter adhesin DsrA protects against an experimental infection in the swine model of chancroid

(2014) William G. Fusco et al.   VACCINE

The Haemophilus ducreyi LspA1 Protein Inhibits Phagocytosis By Using a New Mechanism Involving Activation of C-Terminal Src Kinase

(2014) D. A. Dodd et al.   mBio

Haemophilus ducreyi Hfq Contributes to Virulence Gene Regulation as Cells Enter Stationary Phase

(2014) D. Gangaiah et al.   mBio

Safety and efficacy of MVA85A, a new tuberculosis vaccine, in infants previously vaccinated with BCG: a randomised, placebo-controlled phase 2b trial

(2013) Michele D Tameris et al.   LANCET

CD163 favors Mycobacterium leprae survival and persistence by promoting anti-inflammatory pathways in lepromatous macrophages

(2012) Danielle F. Moura et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Haemophilus ducreyi-Induced Interleukin-10 Promotes a Mixed M1 and M2 Activation Program in Human Macrophages

(2012) Wei Li et al.   INFECTION AND IMMUNITY

Carbon Storage Regulator A Contributes to the Virulence of Haemophilus ducreyi in Humans by Multiple Mechanisms

(2012) Dharanesh Gangaiah et al.   INFECTION AND IMMUNITY

A Human Challenge Model for Mycobacterium tuberculosis Using Mycobacterium bovis Bacille Calmette-Guérin

(2012) Angela M. Minassian et al.   JOURNAL OF INFECTIOUS DISEASES

Permeases of the Sap Transporter Are Required for Cathelicidin Resistance and Virulence of Haemophilus ducreyi in Humans

(2012) S. D. Rinker et al.   JOURNAL OF INFECTIOUS DISEASES

The potential for vaccination in leprosy elimination: new tools for targeted interventions

(2012) Malcolm S Duthie et al.   MEMORIAS DO INSTITUTO OSWALDO CRUZ

The Immunopathobiology of Syphilis: The Manifestations and Course of Syphilis Are Determined by the Level of Delayed-Type Hypersensitivity

(2011) J Andrew Carlson et al.   AMERICAN JOURNAL OF DERMATOPATHOLOGY

Expression of the Flp proteins by Haemophilus ducreyi is necessary for virulence in human volunteers

(2011) Diane M Janowicz et al.   BMC MICROBIOLOGY

Deletion ofmtrCin Haemophilus ducreyi Increases Sensitivity to Human Antimicrobial Peptides and Activates the CpxRA Regulon

(2011) Sherri D. Rinker et al.   INFECTION AND IMMUNITY

Sialylation of Lipooligosaccharides Is Dispensable for the Virulence of Haemophilus ducreyi in Humans

(2011) Stanley M. Spinola et al.   INFECTION AND IMMUNITY

Haemophilus ducreyi Lipooligosaccharides Induce Expression of the Immunosuppressive Enzyme Indoleamine 2,3-Dioxygenase via Type I Interferons and Tumor Necrosis Factor Alpha in Human Dendritic Cells

(2011) Wei Li et al.   INFECTION AND IMMUNITY

A Haemophilus ducreyi CpxR Deletion Mutant Is Virulent in Human Volunteers

(2011) Maria Labandeira-Rey et al.   JOURNAL OF INFECTIOUS DISEASES

Activation of the CpxRA System by Deletion of cpxA Impairs the Ability of Haemophilus ducreyi To Infect Humans

(2010) S. M. Spinola et al.   INFECTION AND IMMUNITY

Immunization with the Haemophilus ducreyi Hemoglobin Receptor HgbA with Adjuvant Monophosphoryl Lipid A Protects Swine from a Homologous but Not a Heterologous Challenge

(2010) W. G. Fusco et al.   INFECTION AND IMMUNITY

Haemophilus ducreyi SapA Contributes to Cathelicidin Resistance and Virulence in Humans

(2010) K. L. B. Mount et al.   INFECTION AND IMMUNITY

IDO Activates Regulatory T Cells and Blocks Their Conversion into Th17-Like T Cells

(2009) B. Baban et al.   JOURNAL OF IMMUNOLOGY

Inactivation of theHaemophilus ducreyi luxSGene Affects the Virulence of This Pathogen in Human Subjects

(2009) Maria Labandeira‐Rey et al.   JOURNAL OF INFECTIOUS DISEASES

Experimental Infection of Human Volunteers withHaemophilus ducreyi:Fifteen Years of Clinical Data and Experience

(2009) Diane M. Janowicz et al.   JOURNAL OF INFECTIOUS DISEASES

Mechanism of Human Natural Killer Cell Activation byHaemophilus ducreyi

(2009) Wei Li et al.   JOURNAL OF INFECTIOUS DISEASES

A Fibrinogen-Binding Lipoprotein Contributes to the Virulence ofHaemophilus ducreyiin Humans

(2009) Margaret E. Bauer et al.   JOURNAL OF INFECTIOUS DISEASES

Evaluation of the Repertoire of the TonB‐Dependent Receptors ofHaemophilus ducreyifor Their Role in Virulence in Humans

(2008) Isabelle Leduc et al.   JOURNAL OF INFECTIOUS DISEASES

The Enterobacterial Common Antigen–Like Gene Cluster ofHaemophilus ducreyiContributes to Virulence in Humans

(2008) Keith E. Banks et al.   JOURNAL OF INFECTIOUS DISEASES