Role of HCA2 in Regulating Intestinal Homeostasis and Suppressing Colon Carcinogenesis
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Title
Role of HCA2 in Regulating Intestinal Homeostasis and Suppressing Colon Carcinogenesis
Authors
Keywords
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Journal
Frontiers in Immunology
Volume 12, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2021-02-23
DOI
10.3389/fimmu.2021.606384
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Note: Only part of the references are listed.- Hydroxycarboxylic Acid Receptor 2 Is a Zika Virus Restriction Factor That Can Be Induced by Zika Virus Infection Through the IRE1-XBP1 Pathway
- (2020) Xiaocao Ma et al. Frontiers in Cellular and Infection Microbiology
- Niacin fine-tunes energy homeostasis through canonical GPR109A signaling
- (2019) Lingyan Ye et al. FASEB JOURNAL
- A Comprehensive Review and Update on the Pathogenesis of Inflammatory Bowel Disease
- (2019) Qingdong Guan Journal of Immunology Research
- Niacin Ameliorates Hepatic Steatosis by Inhibiting De Novo Lipogenesis Via a GPR109A-Mediated PKC–ERK1/2–AMPK Signaling Pathway in C57BL/6 Mice Fed a High-Fat Diet
- (2019) Lingyan Ye et al. JOURNAL OF NUTRITION
- 4-Hydroxynonenal-induced GPR109A (HCA2 receptor) activation elicits bipolar responses, Gαi -mediated anti-inflammatory effects and Gβγ -mediated cell death
- (2018) Jaya Gautam et al. BRITISH JOURNAL OF PHARMACOLOGY
- Fiber-Mediated Nourishment of Gut Microbiota Protects against Diet-Induced Obesity by Restoring IL-22-Mediated Colonic Health
- (2018) Jun Zou et al. Cell Host & Microbe
- Sodium Butyrate Attenuates Diarrhea in Weaned Piglets and Promotes Tight Junction Protein Expression in Colon in a GPR109A-Dependent Manner
- (2018) Wenqian Feng et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Gpr109a Limits Microbiota-Induced IL-23 Production To Constrain ILC3-Mediated Colonic Inflammation
- (2018) Brinda Bhatt et al. JOURNAL OF IMMUNOLOGY
- Recent Advances: The Imbalance of Cytokines in the Pathogenesis of Inflammatory Bowel Disease
- (2017) Qingdong Guan et al. MEDIATORS OF INFLAMMATION
- An Update on Inflammatory Bowel Disease
- (2017) Tomoko Sairenji et al. PRIMARY CARE
- Hydroxy-Carboxylic Acid Receptor Actions in Metabolism
- (2017) Stefan Offermanns TRENDS IN ENDOCRINOLOGY AND METABOLISM
- (Dis)Trust your gut: the gut microbiome in age-related inflammation, health, and disease
- (2017) Thomas W. Buford Microbiome
- Activated niacin receptor HCA2 inhibits chemoattractant-mediated macrophage migration via Gβγ/PKC/ERK1/2 pathway and heterologous receptor desensitization
- (2017) Ying Shi et al. Scientific Reports
- Effect of Niacin on Inflammation and Angiogenesis in a Murine Model of Ulcerative Colitis
- (2017) Hesham Aly Salem et al. Scientific Reports
- Inflammasome Complexes: Emerging Mechanisms and Effector Functions
- (2016) Vijay A.K. Rathinam et al. CELL
- Niacin receptor GPR109A inhibits insulin secretion and is down-regulated in type 2 diabetic islet beta-cells
- (2016) Na Wang et al. GENERAL AND COMPARATIVE ENDOCRINOLOGY
- Dietary Fiber and Bacterial SCFA Enhance Oral Tolerance and Protect against Food Allergy through Diverse Cellular Pathways
- (2016) Jian Tan et al. Cell Reports
- Prevalence of Inflammatory Bowel Disease Among Adults Aged ≥18 Years — United States, 2015
- (2016) James M. Dahlhamer et al. MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT
- Status of colitis-associated cancer in ulcerative colitis
- (2016) Tetsushi Kinugasa et al. World Journal of Gastrointestinal Oncology
- Inflammasomes in pancreatic physiology and disease
- (2015) Rafaz Hoque et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Lack of soluble fiber drives diet-induced adiposity in mice
- (2015) Benoit Chassaing et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Characterization of the hydroxycarboxylic acid receptor 2 in cats
- (2015) E.C. Graff et al. DOMESTIC ANIMAL ENDOCRINOLOGY
- Interleukin-12 and -23 Control Plasticity of CD127+ Group 1 and Group 3 Innate Lymphoid Cells in the Intestinal Lamina Propria
- (2015) Jochem H. Bernink et al. IMMUNITY
- Divergent responses of viral and bacterial communities in the gut microbiome to dietary disturbances in mice
- (2015) Adina Howe et al. ISME Journal
- Anti-inflammatory effects of BHBA in both in vivo and in vitro Parkinson’s disease models are mediated by GPR109A-dependent mechanisms
- (2015) Shou-Peng Fu et al. Journal of Neuroinflammation
- The biology of innate lymphoid cells
- (2015) David Artis et al. NATURE
- Nutritional or pharmacological activation of HCA2 ameliorates neuroinflammation
- (2015) Stefan Offermanns et al. TRENDS IN MOLECULAR MEDICINE
- Metabolite-sensing receptors GPR43 and GPR109A facilitate dietary fibre-induced gut homeostasis through regulation of the inflammasome
- (2015) Laurence Macia et al. Nature Communications
- IFN Induces DNA Methylation-Silenced GPR109A Expression via pSTAT1/p300 and H3K18 Acetylation in Colon Cancer
- (2015) K. Bardhan et al. Cancer Immunology Research
- Tributyrin Supplementation Protects Mice from Acute Ethanol-Induced Gut Injury
- (2014) Gail A. Cresci et al. ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH
- Activation of Gpr109a, Receptor for Niacin and the Commensal Metabolite Butyrate, Suppresses Colonic Inflammation and Carcinogenesis
- (2014) Nagendra Singh et al. IMMUNITY
- BHBA Suppresses LPS-Induced Inflammation in BV-2 Cells by Inhibiting NF-κB Activation
- (2014) Shou-Peng Fu et al. MEDIATORS OF INFLAMMATION
- Retinoic acid primes human dendritic cells to induce gut-homing, IL-10-producing regulatory T cells
- (2014) G Bakdash et al. Mucosal Immunology
- Intestinal microbiota: A source of novel biomarkers in inflammatory bowel diseases?
- (2013) David Berry et al. BEST PRACTICE & RESEARCH IN CLINICAL GASTROENTEROLOGY
- The Niacin/Butyrate Receptor GPR109A Suppresses Mammary Tumorigenesis by Inhibiting Cell Survival
- (2013) S. Elangovan et al. CANCER RESEARCH
- GSK256073, a selective agonist of G-protein coupled receptor 109A (GPR109A) reduces serum glucose in subjects with type 2 diabetes mellitus
- (2013) R. L. Dobbins et al. DIABETES OBESITY & METABOLISM
- The role of HCA2 (GPR109A) in regulating macrophage function
- (2013) Kambiz Zandi-Nejad et al. FASEB JOURNAL
- The Microbial Metabolites, Short-Chain Fatty Acids, Regulate Colonic Treg Cell Homeostasis
- (2013) P. M. Smith et al. SCIENCE
- Anti-Inflammatory Effects of Nicotinic Acid in Human Monocytes Are Mediated by GPR109A Dependent Mechanisms
- (2012) Janet E. Digby et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Migratory, and not lymphoid-resident, dendritic cells maintain peripheral self-tolerance and prevent autoimmunity via induction of iTreg cells
- (2012) C. Vitali et al. BLOOD
- Gut microbiota accelerate tumor growth via c-jun and STAT3 phosphorylation in APC Min/+ mice
- (2012) Yinghui Li et al. CARCINOGENESIS
- Role of HCA2 (GPR109A) in nicotinic acid and fumaric acid ester-induced effects on the skin
- (2012) Julien Hanson et al. PHARMACOLOGY & THERAPEUTICS
- Inflammation-Mediated Memory Dysfunction and Effects of a Ketogenic Diet in a Murine Model of Multiple Sclerosis
- (2012) Do Young Kim et al. PLoS One
- Diet-Induced Dysbiosis of the Intestinal Microbiota and the Effects on Immunity and Disease
- (2012) Kirsty Brown et al. Nutrients
- Structural segregation of gut microbiota between colorectal cancer patients and healthy volunteers
- (2011) Tingting Wang et al. ISME Journal
- Nicotinic acid inhibits progression of atherosclerosis in mice through its receptor GPR109A expressed by immune cells
- (2011) Martina Lukasova et al. JOURNAL OF CLINICAL INVESTIGATION
- Intestinal homeostasis and its breakdown in inflammatory bowel disease
- (2011) Kevin J. Maloy et al. NATURE
- Enterotypes of the human gut microbiome
- (2011) Manimozhiyan Arumugam et al. NATURE
- International Union of Basic and Clinical Pharmacology. LXXXII: Nomenclature and Classification of Hydroxy-carboxylic Acid Receptors (GPR81, GPR109A, and GPR109B)
- (2011) S. Offermanns et al. PHARMACOLOGICAL REVIEWS
- D-β-Hydroxybutyrate Is Protective in Mouse Models of Huntington's Disease
- (2011) Soyeon Lim et al. PLoS One
- The Nlrp3 inflammasome: contributions to intestinal homeostasis
- (2011) Md. Hasan Zaki et al. TRENDS IN IMMUNOLOGY
- Niacin attenuates lung inflammation and improves survival during sepsis by downregulating the nuclear factor-κB pathway*
- (2010) Woon Yong Kwon et al. CRITICAL CARE MEDICINE
- The NLRP3 Inflammasome Protects against Loss of Epithelial Integrity and Mortality during Experimental Colitis
- (2010) Md. Hasan Zaki et al. IMMUNITY
- Nicotinic acid– and monomethyl fumarate–induced flushing involves GPR109A expressed by keratinocytes and COX-2–dependent prostanoid formation in mice
- (2010) Julien Hanson et al. JOURNAL OF CLINICAL INVESTIGATION
- Innate lymphoid cells drive interleukin-23-dependent innate intestinal pathology
- (2010) Sofia Buonocore et al. NATURE
- Activation of -Catenin in Dendritic Cells Regulates Immunity Versus Tolerance in the Intestine
- (2010) S. Manicassamy et al. SCIENCE
- Induction of Colonic Regulatory T Cells by Indigenous Clostridium Species
- (2010) K. Atarashi et al. SCIENCE
- Niacin stimulates adiponectin secretion through the GPR109A receptor
- (2009) Eric P. Plaisance et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- The protective effect of the ketogenic diet on traumatic brain injury-induced cell death in juvenile rats
- (2009) Zhi-Gang Hu et al. BRAIN INJURY
- Managing gut health through nutrition
- (2009) M. Choct BRITISH POULTRY SCIENCE
- GPR109A Is a G-protein-Coupled Receptor for the Bacterial Fermentation Product Butyrate and Functions as a Tumor Suppressor in Colon
- (2009) M. Thangaraju et al. CANCER RESEARCH
- Intestinal Lamina Propria Dendritic Cell Subsets Have Different Origin and Functions
- (2009) Chen Varol et al. IMMUNITY
- Colonic Gene Expression in Conventional and Germ-Free Mice with a Focus on the Butyrate Receptor GPR109A and the Butyrate Transporter SLC5A8
- (2009) Gail A. Cresci et al. JOURNAL OF GASTROINTESTINAL SURGERY
- Microbial NAD Metabolism: Lessons from Comparative Genomics
- (2009) F. Gazzaniga et al. MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS
- Carcinogenesis in IBD: potential targets for the prevention of colorectal cancer
- (2009) Linda A. Feagins et al. Nature Reviews Gastroenterology & Hepatology
- GPR109A, GPR109B and GPR81, a family of hydroxy-carboxylic acid receptors
- (2009) Kashan Ahmed et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- XBP1 Links ER Stress to Intestinal Inflammation and Confers Genetic Risk for Human Inflammatory Bowel Disease
- (2008) Arthur Kaser et al. CELL
- Neuroprotection in Diet-Induced Ketotic Rat Brain after Focal Ischemia
- (2008) Michelle A Puchowicz et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Elucidation of signaling and functional activities of an orphan GPCR, GPR81
- (2008) Hongfei Ge et al. JOURNAL OF LIPID RESEARCH
- 3-(1H-Tetrazol-5-yl)-1,4,5,6-tetrahydro-cyclopentapyrazole (MK-0354): A Partial Agonist of the Nicotinic Acid Receptor, G-Protein Coupled Receptor 109a, with Antilipolytic but No Vasodilatory Activity in Mice
- (2008) Graeme Semple et al. JOURNAL OF MEDICINAL CHEMISTRY
- Increased total and high–molecular weight adiponectin after extended-release niacin
- (2008) Eric P. Plaisance et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- Nicotinic Acid: Pharmacological Effects and Mechanisms of Action
- (2007) Andreas Gille et al. Annual Review of Pharmacology and Toxicology
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