METTL3-mediated m6A modification of ZBTB4 mRNA is involved in the smoking-induced EMT in cancer of the lung

METTL3/YTHDF2 m 6 A axis promotes tumorigenesis by degrading SETD7 and KLF4 mRNAs in bladder cancer

(2020) Haiyun Xie et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

The emerging roles of N6-methyladenosine (m6A) deregulation in liver carcinogenesis

(2020) Mengnuo Chen et al.   Molecular Cancer

Molecular Mechanisms Driving mRNA Degradation by m6A Modification

(2020) Yujin Lee et al.   TRENDS IN GENETICS

Silencing METTL3 inhibits the proliferation and invasion of osteosarcoma by regulating ATAD2

(2020) Lei Zhou et al.   BIOMEDICINE & PHARMACOTHERAPY

Increased m6A RNA modification is related to the inhibition of the Nrf2-mediated antioxidant response in di-(2-ethylhexyl) phthalate-induced prepubertal testicular injury

(2020) Tian-Xin Zhao et al.   ENVIRONMENTAL POLLUTION

The m6A methyltransferase METTL3 promotes bladder cancer progression via AFF4/NF-κB/MYC signaling network

(2019) Maosheng Cheng et al.   ONCOGENE

m6A methylation controls pluripotency of porcine induced pluripotent stem cells by targeting SOCS3/JAK2/STAT3 pathway in a YTHDF1/YTHDF2-orchestrated manner

(2019) Ruifan Wu et al.   Cell Death & Disease

Dynamic m6A mRNA methylation reveals the role of METTL3-m6A-CDCP1 signaling axis in chemical carcinogenesis

(2019) Fan Yang et al.   ONCOGENE

The Critical Role of RNA m6A Methylation in Cancer

(2019) Qing Lan et al.   CANCER RESEARCH

Where, When, and How: Context-Dependent Functions of RNA Methylation Writers, Readers, and Erasers

(2019) Hailing Shi et al.   MOLECULAR CELL

Mettl3-mediated mRNA m6A methylation promotes dendritic cell activation

(2019) Huamin Wang et al.   Nature Communications

Excessive miR-25-3p maturation via N6-methyladenosine stimulated by cigarette smoke promotes pancreatic cancer progression

(2019) Jialiang Zhang et al.   Nature Communications

METTL3 facilitates tumor progression via an m6A-IGF2BP2-dependent mechanism in colorectal carcinoma

(2019) Ting Li et al.   Molecular Cancer

Andrographolide antagonizes the cigarette smoke-induced epithelial-mesenchymal transition and pulmonary dysfunction through anti-inflammatory inhibiting HOTAIR

(2019) Haibo Xia et al.   TOXICOLOGY

RNA m6A methylation regulates the epithelial mesenchymal transition of cancer cells and translation of Snail

(2019) Xinyao Lin et al.   Nature Communications

Reduced m6A modification predicts malignant phenotypes and augmented Wnt/PI3K-Akt signaling in gastric cancer

(2019) Cheng Zhang et al.   Cancer Medicine

Identification of risk loci and a polygenic risk score for lung cancer: a large-scale prospective cohort study in Chinese populations

(2019) Juncheng Dai et al.   Lancet Respiratory Medicine

METTL3-mediated m6A modification of HDGF mRNA promotes gastric cancer progression and has prognostic significance

(2019) Qiang Wang et al.   GUT

Electronic-cigarette smoke induces lung adenocarcinoma and bladder urothelial hyperplasia in mice

(2019) Moon-shong Tang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tumor suppressive ZBTB4 inhibits cell growth by regulating cell cycle progression and apoptosis in Ewing sarcoma

(2018) Yongxin Yu et al.   BIOMEDICINE & PHARMACOTHERAPY

Role of N 6 -methyladenosine modification in cancer

(2018) Xiaolan Deng et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

m6A demethylase FTO regulates dopaminergic neurotransmission deficits caused by arsenite

(2018) LuLu Bai et al.   TOXICOLOGICAL SCIENCES

Involvement of HIF-1α-regulated miR-21, acting via the Akt/NF-κB pathway, in malignant transformation of HBE cells induced by cigarette smoke extract

(2018) Lu Lu et al.   TOXICOLOGY LETTERS

N6-methyladenosine links RNA metabolism to cancer progression

(2018) Dongjun Dai et al.   Cell Death & Disease

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2018) Freddie Bray et al.   CA-A CANCER JOURNAL FOR CLINICIANS

MicroRNAs and their role in environmental chemical carcinogenesis

(2018) Minghui Li et al.   ENVIRONMENTAL GEOCHEMISTRY AND HEALTH

Circ008913, via miR-889 regulation of DAB2IP/ZEB1, is involved in the arsenite-induced acquisition of CSC-like properties by human keratinocytes in carcinogenesis

(2018) Tian Xiao et al.   Metallomics

STRING v11: protein–protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets

(2018) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

Impaired autophagic flux and p62-mediated EMT are involved in arsenite-induced transformation of L-02 cells

(2017) Xinlu Liu et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

UALCAN: A Portal for Facilitating Tumor Subgroup Gene Expression and Survival Analyses

(2017) Darshan S. Chandrashekar et al.   NEOPLASIA

STAT3-regulated exosomal miR-21 promotes angiogenesis and is involved in neoplastic processes of transformed human bronchial epithelial cells

(2016) Yi Liu et al.   CANCER LETTERS

Loss of the Methyl-CpG–Binding Protein ZBTB4 Alters Mitotic Checkpoint, Increases Aneuploidy, and Promotes Tumorigenesis

(2016) Audrey Roussel-Gervais et al.   CANCER RESEARCH

The m 6 A Methyltransferase METTL3 Promotes Translation in Human Cancer Cells

(2016) Shuibin Lin et al.   MOLECULAR CELL

Effect of Cigarette Smoking on Epithelial to Mesenchymal Transition (EMT) in Lung Cancer

(2016) Trung Vu et al.   Journal of Clinical Medicine

HNRNPA2B1 Is a Mediator of m6A-Dependent Nuclear RNA Processing Events

(2015) Claudio R. Alarcón et al.   CELL

N6-methyladenosine Modulates Messenger RNA Translation Efficiency

(2015) Xiao Wang et al.   CELL

Epithelial-mesenchymal transition and cancer stem cells, mediated by a long non-coding RNA, HOTAIR, are involved in cell malignant transformation induced by cigarette smoke extract

(2015) Yi Liu et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Posttranscriptional silencing of the lncRNA MALAT1 by miR-217 inhibits the epithelial–mesenchymal transition via enhancer of zeste homolog 2 in the malignant transformation of HBE cells induced by cigarette smoke extract

(2015) Lu Lu et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Epigenetic silencing of microRNA-218 via EZH2-mediated H3K27 trimethylation is involved in malignant transformation of HBE cells induced by cigarette smoke extract

(2014) Bairu Wang et al.   ARCHIVES OF TOXICOLOGY

The Transcriptional Repressor ZBTB4 Regulates EZH2 Through a MicroRNA-ZBTB4-Specificity Protein Signaling Axis

(2014) Won Seok Yang et al.   NEOPLASIA

New molecular insights in tobacco-induced lung cancer

(2013) Giuseppe Tonini et al.   Future Oncology

Detection of Lung Dysfunction Using Ventilation and Perfusion SPECT in a Mouse Model of Chronic Cigarette Smoke Exposure

(2013) B. N. Jobse et al.   JOURNAL OF NUCLEAR MEDICINE

N6-methyladenosine-dependent regulation of messenger RNA stability

(2013) Xiao Wang et al.   NATURE

NF-κB-Mediated Inflammation Leading to EMT via miR-200c Is Involved in Cell Transformation Induced By Cigarette Smoke Extract

(2013) Yue Zhao et al.   TOXICOLOGICAL SCIENCES

Induction of the Transcriptional Repressor ZBTB4 in Prostate Cancer Cells by Drug-Induced Targeting of MicroRNA-17-92/106b-25 Clusters

(2012) K. Kim et al.   MOLECULAR CANCER THERAPEUTICS

Tumour size measurement in a mouse model using high resolution MRI

(2012) Mikael Montelius et al.   BMC MEDICAL IMAGING

Cigarette smoking and lung cancer-relative risk estimates for the major histological types from a pooled analysis of case-control studies

(2011) Beate Pesch et al.   INTERNATIONAL JOURNAL OF CANCER

Identification of oncogenic microRNA-17-92/ZBTB4/specificity protein axis in breast cancer

(2011) K Kim et al.   ONCOGENE

Epigenetic silencing of O6 -methylguanine DNA methyltransferase gene in NiS-transformed cells

(2008) Weidong Ji et al.   CARCINOGENESIS

Zbtb4 represses transcription of P21CIP1 and controls the cellular response to p53 activation

(2008) Axel Weber et al.   EMBO JOURNAL