Glycyrrhetinic Acid Protects Renal Tubular Cells against Oxidative Injury via Reciprocal Regulation of JNK-Connexin 43-Thioredoxin 1 Signaling

Blocking Connexin-43 mediated hemichannel activity protects against early tubular injury in experimental chronic kidney disease

(2020) Gareth W. Price et al.   Cell Communication and Signaling

CD38 inhibition by apigenin ameliorates mitochondrial oxidative stress through restoration of the intracellular NAD+/NADH ratio and Sirt3 activity in renal tubular cells in diabetic rats

(2020) Yoshio Ogura et al.   Aging-US

Oxidative stress and kidney function: a brief update

(2019) Giuseppe Coppolino et al.   CURRENT PHARMACEUTICAL DESIGN

Osteocytic connexin 43 channels affect fracture healing

(2019) Yunhe Chen et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Total Extracts of Abelmoschus manihot L. Attenuates Adriamycin-Induced Renal Tubule Injury via Suppression of ROS-ERK1/2-Mediated NLRP3 Inflammasome Activation

(2019) Wei Li et al.   Frontiers in Pharmacology

Chronic Kidney Disease Diagnosis and Management

(2019) Teresa K. Chen et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Cleaved Caspase-3 Transcriptionally Regulates Angiogenesis-Promoting Chemotherapy Resistance

(2019) Antoine Bernard et al.   CANCER RESEARCH

Oxidative stress-mediated TXNIP loss causes RPE dysfunction

(2019) Min Ji Cho et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Comparative study on the plasma lipid oxidation induced by peroxynitrite and peroxyl radicals and its inhibition by antioxidants

(2019) Mayuko Morita et al.   FREE RADICAL RESEARCH

A Comprehensive Review on MAPK: A Promising Therapeutic Target in Cancer

(2019) Braicu et al.   Cancers

Quercetin Attenuates Decrease of Thioredoxin Expression Following Focal Cerebral Ischemia and Glutamate-induced Neuronal Cell Damage

(2019) Dong-Ju Park et al.   NEUROSCIENCE

Gap junction gene and protein families: Connexins, innexins, and pannexins

(2018) Eric C. Beyer et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Inhibition of curcumin on influenza A virus infection and influenzal pneumonia via oxidative stress, TLR2/4, p38/JNK MAPK and NF-κB pathways

(2018) Jianping Dai et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Smurf1 regulates macrophage proliferation, apoptosis and migration via JNK and p38 MAPK signaling pathways

(2018) Jing Guo et al.   MOLECULAR IMMUNOLOGY

Thioredoxin-Interacting Protein (TXNIP) in Cerebrovascular and Neurodegenerative Diseases: Regulation and Implication

(2018) Sanaz Nasoohi et al.   MOLECULAR NEUROBIOLOGY

Repurposing Auranofin, Ebselen, and PX-12 as Antimicrobial Agents Targeting the Thioredoxin System

(2018) Holly C. May et al.   Frontiers in Microbiology

Extracellular Matrix Remodeling Regulates Glucose Metabolism through TXNIP Destabilization

(2018) William J. Sullivan et al.   CELL

Connexin 43: a New Therapeutic Target Against Chronic Kidney Disease

(2018) Niki Prakoura et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Liquorice (Glycyrrhiza glabra ): A phytochemical and pharmacological review

(2018) Giulia Pastorino et al.   PHYTOTHERAPY RESEARCH

MAGE genes in the kidney: identification of MAGED2 as upregulated during kidney injury and in stressed tubular cells

(2018) Lara Valiño-Rivas et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Targeting different domains of gap junction protein to control malignant glioma

(2017) Jun Wang et al.   NEURO-ONCOLOGY

Cell Signaling with Extracellular Thioredoxin and Thioredoxin-Like Proteins: Insight into Their Mechanisms of Action

(2017) Thierry Léveillard et al.   Oxidative Medicine and Cellular Longevity

Unique proximal tubular cell injury and the development of acute kidney injury in adult patients with minimal change nephrotic syndrome

(2017) Yoshihide Fujigaki et al.   BMC Nephrology

Protein Nutrition and Malnutrition in CKD and ESRD

(2017) Yan Zha et al.   Nutrients

18α-Glycyrrhetinic acid lethality for neuroblastoma cells via de-regulating the Beclin-1/Bcl-2 complex and inducing apoptosis

(2016) Md. Ataur Rahman et al.   BIOCHEMICAL PHARMACOLOGY

Negative feedback regulation of the ERK1/2 MAPK pathway

(2016) David Lake et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Human thioredoxin-1 attenuates the rate of lipopolysaccharide-induced preterm delivery in mice in association with its anti-inflammatory effect

(2016) Fumihiko Namba et al.   PEDIATRIC RESEARCH

Chronic kidney disease

(2015) Albara Said et al.   DM DISEASE-A-MONTH

A novel TXNIP-based mechanism for Cx43-mediated regulation of oxidative drug injury

(2015) Kun Gao et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Upregulation of connexin43 contributes to PX-12-induced oxidative cell death

(2015) Gang Li et al.   TUMOR BIOLOGY

Molecular Markers of Tubulointerstitial Fibrosis and Tubular Cell Damage in Patients with Chronic Kidney Disease

(2015) Shunsaku Nakagawa et al.   PLoS One

Purinergic control of AMPK activation by ATP released through connexin 43 hemichannels - pivotal roles in hemichannel-mediated cell injury

(2014) Y. Chi et al.   JOURNAL OF CELL SCIENCE

The thioredoxin antioxidant system

(2013) Jun Lu et al.   FREE RADICAL BIOLOGY AND MEDICINE

Connexin43 Hemichannel-Mediated Regulation of Connexin43

(2013) Kai Li et al.   PLoS One

Redox Cycling of 1,2-Naphthoquinone by Thioredoxin1 through Cys32 and Cys35 Causes Inhibition of Its Catalytic Activity and Activation of ASK1/p38 Signaling

(2012) Yasuhiro Shinkai et al.   CHEMICAL RESEARCH IN TOXICOLOGY

NADPH oxidase-mediated upregulation of connexin43 contributes to podocyte injury

(2012) Qiaojing Yan et al.   FREE RADICAL BIOLOGY AND MEDICINE

Prevalence of chronic kidney disease in China: a cross-sectional survey

(2012) Luxia Zhang et al.   LANCET

Connexin43 Hemichannels Contribute to Cadmium-Induced Oxidative Stress and Cell Injury

(2011) Xin Fang et al.   ANTIOXIDANTS & REDOX SIGNALING