Suppression of Rheumatoid Arthritis by Enhanced Lymph Node Trafficking of Engineered Interleukin‐10 in Murine Models

Polarization of Rheumatoid Macrophages by TNF Targeting Through an IL-10/STAT3 Mechanism

(2019) Yannick Degboé et al.   Frontiers in Immunology

IL-10 Family Cytokines IL-10 and IL-22: from Basic Science to Clinical Translation

(2019) Wenjun Ouyang et al.   IMMUNITY

The Neonatal Fc Receptor (FcRn): A Misnomer?

(2019) Michal Pyzik et al.   Frontiers in Immunology

Molecular mechanisms underpinning T helper 17 cell heterogeneity and functions in rheumatoid arthritis

(2018) Jan Piet van Hamburg et al.   JOURNAL OF AUTOIMMUNITY

An Albumin-binding Polypeptide Both Targets Cytotoxic T Lymphocyte Vaccines to Lymph Nodes and Boosts Vaccine Presentation by Dendritic Cells

(2018) Peng Wang et al.   Theranostics

F8-IL10: A New Potential Antirheumatic Drug Evaluated by a PET-Guided Translational Approach

(2018) Stefan T.G. Bruijnen et al.   MOLECULAR PHARMACEUTICS

Hepatic FcRn regulates albumin homeostasis and susceptibility to liver injury

(2017) Michal Pyzik et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeting IL-10 Family Cytokines for the Treatment of Human Diseases

(2017) Xiaoting Wang et al.   Cold Spring Harbor Perspectives in Biology

Albumin/vaccine nanocomplexes that assemble in vivo for combination cancer immunotherapy

(2017) Guizhi Zhu et al.   Nature Communications

The Plasticity of Th17 Cells in the Pathogenesis of Rheumatoid Arthritis

(2017) Shigeru Kotake et al.   Journal of Clinical Medicine

A Case of Adalimumab-Induced Pneumonitis in a 45-Year-Old Man with Crohn’s Disease

(2016) James D Reid et al.   Canadian Respiratory Journal

Interleukin-10 paradox: A potent immunoregulatory cytokine that has been difficult to harness for immunotherapy

(2015) Ankit Saxena et al.   CYTOKINE

Serious infection during etanercept, infliximab and adalimumab therapy for rheumatoid arthritis: A literature review

(2015) Colum Downey   International Journal of Rheumatic Diseases

Macrophage IL-10 Blocks CD8+ T Cell-Dependent Responses to Chemotherapy by Suppressing IL-12 Expression in Intratumoral Dendritic Cells

(2014) Brian Ruffell et al.   CANCER CELL

Infection risk in patients with rheumatoid arthritis treated with etanercept or adalimumab

(2014) Yi-Chun Chiang et al.   COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE

IL-10: The Master Regulator of Immunity to Infection

(2014) Kevin N. Couper et al.   JOURNAL OF IMMUNOLOGY

Structure-based programming of lymph-node targeting in molecular vaccines

(2014) Haipeng Liu et al.   NATURE

Murine analogues of etanercept and of F8-IL10 inhibit the progression of collagen-induced arthritis in the mouse

(2013) Fabia Doll et al.   ARTHRITIS RESEARCH & THERAPY

Th17 Cells Express Interleukin-10 Receptor and Are Controlled by Foxp3− and Foxp3+ Regulatory CD4+ T Cells in an Interleukin-10-Dependent Manner

(2011) Samuel Huber et al.   IMMUNITY

The Pathogenesis of Rheumatoid Arthritis

(2011) Iain B. McInnes et al.   NEW ENGLAND JOURNAL OF MEDICINE

Visualizing vascular permeability and lymphatic drainage using labeled serum albumin

(2010) Katrien Vandoorne et al.   ANGIOGENESIS

Enhanced antibody half-life improves in vivo activity

(2010) Jonathan Zalevsky et al.   NATURE BIOTECHNOLOGY

Preclinical characterization of DEKAVIL (F8-IL10), a novel clinical-stage immunocytokine which inhibits the progression of collagen-induced arthritis

(2009) Kathrin Schwager et al.   ARTHRITIS RESEARCH & THERAPY