Streptococcus pyogenes M1T1 Variants Induce an Inflammatory Neutrophil Phenotype Including Activation of Inflammatory Caspases

Whole blood assay as a model for in vitro evaluation of inflammasome activation and subsequent caspase-mediated interleukin-1 beta release

(2019) Thi Anh Thu Tran et al.   PLoS One

Group A Streptococcal S Protein Utilizes Red Blood Cells as Immune Camouflage and Is a Critical Determinant for Immune Evasion

(2019) Igor H. Wierzbicki et al.   Cell Reports

Caspase-1 self-cleavage is an intrinsic mechanism to terminate inflammasome activity

(2018) Dave Boucher et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Neutrophils and Bacterial Immune Evasion

(2018) Scott D. Kobayashi et al.   Journal of Innate Immunity

Proteomic analysis at the sites of clinical infection with invasive Streptococcus pyogenes

(2018) Robert J. Edwards et al.   Scientific Reports

NLRP6 negatively regulates pulmonary host defense in Gram-positive bacterial infection through modulating neutrophil recruitment and function

(2018) Laxman Ghimire et al.   PLoS Pathogens

Staphylococcus aureus promotes receptor‐interacting protein kinase 3‐ and protease‐dependent production of IL‐1β in human neutrophils

(2018) Silvie Kremserova et al.   JOURNAL OF LEUKOCYTE BIOLOGY

The Inflammasome Drives GSDMD-Independent Secondary Pyroptosis and IL-1 Release in the Absence of Caspase-1 Protease Activity

(2017) Katharina S. Schneider et al.   Cell Reports

Neutrophils to the ROScue: Mechanisms of NADPH Oxidase Activation and Bacterial Resistance

(2017) Giang T. Nguyen et al.   Frontiers in Cellular and Infection Microbiology

Group A streptococcal M protein activates the NLRP3 inflammasome

(2017) J. Andrés Valderrama et al.   Nature Microbiology

Type I Interferon Signaling Prevents IL-1β-Driven Lethal Systemic Hyperinflammation during Invasive Bacterial Infection of Soft Tissue

(2016) Virginia Castiglia et al.   Cell Host & Microbe

Epidemiology of Invasive Group A Streptococcal Infections in the United States, 2005–2012

(2016) George E. Nelson et al.   CLINICAL INFECTIOUS DISEASES

Differential compartmentalization of Streptococcus pyogenes virulence factors and host protein binding properties as a mechanism for host adaptation

(2016) Ola Kilsgård et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Neutrophil pyroptosis mediates pathology of P. aeruginosa lung infection in the absence of the NADPH oxidase NOX2

(2016) J-C Ryu et al.   Mucosal Immunology

Cytosolic Replication of Group A Streptococcus in Human Macrophages

(2016) Alan M. O’Neill et al.   mBio

Comparative Genomics of Streptococcus pyogenes M1 isolates differing in virulence and propensity to cause systemic infection in mice

(2015) Anne Fiebig et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Group A Streptococcus Modulates Host Inflammation by Manipulating Polymorphonuclear Leukocyte Cell Death Responses

(2015) James A. Tsatsaronis et al.   Journal of Innate Immunity

Inflammasome/IL-1β Responses to Streptococcal Pathogens

(2015) Christopher N. LaRock et al.   Frontiers in Immunology

Host Responses to Group A Streptococcus: Cell Death and Inflammation

(2014) James A. Tsatsaronis et al.   PLoS Pathogens

Neutrophil-Derived Cytokines: Facts Beyond Expression

(2014) Cristina Tecchio et al.   Frontiers in Immunology

Toxin–antitoxin-stabilized reporter plasmids for biophotonic imaging of Group A streptococcus

(2013) Jacelyn M. S. Loh et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Neutrophils in Sepsis

(2013) Eric Kipnis   CRITICAL CARE MEDICINE

Pyroptotic cells externalize eat-me and release find-me signals and are efficiently engulfed by macrophages

(2013) Qiang Wang et al.   INTERNATIONAL IMMUNOLOGY

Plasmin(ogen) Acquisition by Group A Streptococcus Protects against C3b-Mediated Neutrophil Killing

(2013) Diane Ly et al.   Journal of Innate Immunity

The function of neutrophils in sepsis

(2012) Melissa A. Kovach et al.   CURRENT OPINION IN INFECTIOUS DISEASES

Caspase-4 Is Required for Activation of Inflammasomes

(2012) G. Sollberger et al.   JOURNAL OF IMMUNOLOGY

Peculiarities of cell death mechanisms in neutrophils

(2011) B Geering et al.   CELL DEATH AND DIFFERENTIATION

Molecular insight into invasive group A streptococcal disease

(2011) Jason N. Cole et al.   NATURE REVIEWS MICROBIOLOGY

Neutrophil clearance: when the party is over, clean-up begins

(2011) Donna L. Bratton et al.   TRENDS IN IMMUNOLOGY

Differential Requirement for Caspase-1 Autoproteolysis in Pathogen-Induced Cell Death and Cytokine Processing

(2010) Petr Broz et al.   Cell Host & Microbe

Parameters Governing Invasive Disease Propensity of Non-M1 Serotype Group A Streptococci

(2010) Peter G. Maamary et al.   Journal of Innate Immunity

Plasmid pSM19035, a model to study stable maintenance in Firmicutes

(2010) Virginia S. Lioy et al.   PLASMID

Cholinergic Neural Signals to the Spleen Down-Regulate Leukocyte Trafficking via CD11b

(2009) J. M. Huston et al.   JOURNAL OF IMMUNOLOGY

Epidemiology of Severe Streptococcus pyogenes Disease in Europe

(2008) T. L. Lamagni et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Incompetence of Neutrophils to Invasive Group A streptococcus Is Attributed to Induction of Plural Virulence Factors by Dysfunction of a Regulator

(2008) Manabu Ato et al.   PLoS One