Using scRNA-seq to Identify Transcriptional Variation in the Malaria Parasite Ookinete Stage

An epigenetic map of malaria parasite development from host to vector

(2020) Kathrin Witmer et al.   Scientific Reports

Determining cell type abundance and expression from bulk tissues with digital cytometry

(2019) Aaron M. Newman et al.   NATURE BIOTECHNOLOGY

The Malaria Cell Atlas: Single parasite transcriptomes across the complete Plasmodium life cycle

(2019) Virginia M. Howick et al.   SCIENCE

The male mosquito contribution towards malaria transmission: Mating influences the Anopheles female midgut transcriptome and increases female susceptibility to human malaria parasites

(2019) Farah Aida Dahalan et al.   PLoS Pathogens

Comparative Heterochromatin Profiling Reveals Conserved and Unique Epigenome Signatures Linked to Adaptation and Development of Malaria Parasites

(2018) Sabine A. Fraschka et al.   Cell Host & Microbe

scmap: projection of single-cell RNA-seq data across data sets

(2018) Vladimir Yu Kiselev et al.   NATURE METHODS

Single-Cell Transcriptome Profiling of Protozoan and Metazoan Parasites

(2018) Christopher Nötzel et al.   TRENDS IN PARASITOLOGY

A Specific PfEMP1 Is Expressed in P. falciparum Sporozoites and Plays a Role in Hepatocyte Infection

(2018) Gigliola Zanghì et al.   Cell Reports

Single-cell RNA-seq reveals hidden transcriptional variation in malaria parasites

(2018) Adam J Reid et al.   eLife

M3Drop: dropout-based feature selection for scRNASeq

(2018) Tallulah S Andrews et al.   BIOINFORMATICS

The Plasmodium LAP complex affects crystalloid biogenesis and oocyst cell division

(2018) Sadia Saeed et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Single-cell RNA sequencing reveals a signature of sexual commitment in malaria parasites

(2017) Asaf Poran et al.   NATURE

SC3: consensus clustering of single-cell RNA-seq data

(2017) Vladimir Yu Kiselev et al.   NATURE METHODS

Photosensitized INA-Labelled protein 1 (PhIL1) is novel component of the inner membrane complex and is required for Plasmodium parasite development

(2017) Ekta Saini et al.   Scientific Reports

Epigenetic regulation of Plasmodium falciparum clonally variant gene expression during development in Anopheles gambiae

(2017) Elena Gómez-Díaz et al.   Scientific Reports

Epigenetic Roulette in Blood Stream Plasmodium: Gambling on Sex

(2016) Andrew P. Waters   PLoS Pathogens

Malaria parasite CelTOS targets the inner leaflet of cell membranes for pore-dependent disruption

(2016) John R Jimah et al.   eLife

The conserved clag multigene family of malaria parasites: Essential roles in host–pathogen interaction

(2015) Ankit Gupta et al.   DRUG RESISTANCE UPDATES

HISAT: a fast spliced aligner with low memory requirements

(2015) Daehwan Kim et al.   NATURE METHODS

Genome-Wide Identification of the Target Genes of AP2-O, a Plasmodium AP2-Family Transcription Factor

(2015) Izumi Kaneko et al.   PLoS Pathogens

A Plasmodium Phospholipase Is Involved in Disruption of the Liver Stage Parasitophorous Vacuole Membrane

(2015) Paul-Christian Burda et al.   PLoS Pathogens

HTSeq--a Python framework to work with high-throughput sequencing data

(2014) S. Anders et al.   BIOINFORMATICS

Heterochromatin Protein 1 Secures Survival and Transmission of Malaria Parasites

(2014) Nicolas M.B. Brancucci et al.   Cell Host & Microbe

Epigenetic memory takes center stage in the survival strategy of malaria parasites

(2014) Till S Voss et al.   CURRENT OPINION IN MICROBIOLOGY

The Plasmodium bottleneck: malaria parasite losses in the mosquito vector

(2014) Ryan C Smith et al.   MEMORIAS DO INSTITUTO OSWALDO CRUZ

The dynamics and regulators of cell fate decisions are revealed by pseudotemporal ordering of single cells

(2014) Cole Trapnell et al.   NATURE BIOTECHNOLOGY

Full-length RNA-seq from single cells using Smart-seq2

(2014) Simone Picelli et al.   Nature Protocols

featureCounts: an efficient general purpose program for assigning sequence reads to genomic features

(2013) Y. Liao et al.   BIOINFORMATICS

Vector transmission regulates immune control of Plasmodium virulence

(2013) Philip J. Spence et al.   NATURE

Accounting for technical noise in single-cell RNA-seq experiments

(2013) Philip Brennecke et al.   NATURE METHODS

Unique apicomplexan IMC sub-compartment proteins are early markers for apical polarity in the malaria parasite

(2013) B. Poulin et al.   Biology Open

Transcriptional variation in the malaria parasite Plasmodium falciparum

(2012) N. Rovira-Graells et al.   GENOME RESEARCH

Evolution and Architecture of the Inner Membrane Complex in Asexual and Sexual Stages of the Malaria Parasite

(2012) M. Kono et al.   MOLECULAR BIOLOGY AND EVOLUTION

A global map of dominant malaria vectors

(2012) Marianne E Sinka et al.   Parasites & Vectors

PbGEST mediates malaria transmission to both mosquito and vertebrate host

(2011) Arthur M. Talman et al.   MOLECULAR MICROBIOLOGY

Heterochromatin formation in bistable chromatin domains controls the epigenetic repression of clonally variant Plasmodium falciparum genes linked to erythrocyte invasion

(2011) Valerie M. Crowley et al.   MOLECULAR MICROBIOLOGY

Genome-wide Analysis of Heterochromatin Associates Clonally Variant Gene Regulation with Perinuclear Repressive Centers in Malaria Parasites

(2009) Jose-Juan Lopez-Rubio et al.   Cell Host & Microbe

A Novel Family of Apicomplexan Glideosome-associated Proteins with an Inner Membrane-anchoring Role

(2009) Hayley E. Bullen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of a transcription factor in the mosquito-invasive stage of malaria parasites

(2009) Masao Yuda et al.   MOLECULAR MICROBIOLOGY

Dynamic histone H3 epigenome marking during the intraerythrocytic cycle of Plasmodium falciparum

(2009) A. M. Salcedo-Amaya et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Plasmodium falciparum Heterochromatin Protein 1 Marks Genomic Loci Linked to Phenotypic Variation of Exported Virulence Factors

(2009) Christian Flueck et al.   PLoS Pathogens

Antigenic Variation in Plasmodium falciparum

(2008) Artur Scherf et al.   Annual Review of Microbiology

Reverse genetics screen identifies six proteins important for malaria development in the mosquito

(2008) Andrea Ecker et al.   MOLECULAR MICROBIOLOGY