Discrepancies on the Role of Oxygen Gradient and Culture Condition on Mesenchymal Stem Cell Fate

Comparative Effect of MSC Secretome to MSC Co-culture on Cardiomyocyte Gene Expression Under Hypoxic Conditions in vitro

(2020) Nina Kastner et al.   Frontiers in Bioengineering and Biotechnology

Relevance of Oxygen Concentration in Stem Cell Culture for Regenerative Medicine

(2019) Cristina Mas-Bargues et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Grow with the Flow: When Morphogenesis Meets Microfluidics

(2019) Pinak Samal et al.   ADVANCED MATERIALS

Hypoxia impacts human MSC response to substrate stiffness during chondrogenic differentiation

(2019) Daniel A. Foyt et al.   Acta Biomaterialia

Effects of hypoxia on differentiation of mesenchymal stem cells

(2019) Wei Chen et al.   Current Stem Cell Research & Therapy

Secretome from hypoxia-conditioned adipose-derived mesenchymal stem cells promotes the healing of gastric mucosal injury in a rodent model

(2018) Xianfeng Xia et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Hypoxia with Wharton’s jelly mesenchymal stem cell coculture maintains stemness of umbilical cord blood-derived CD34+ cells

(2018) Dewan Zhao et al.   Stem Cell Research & Therapy

Transportable system enabling multiple irradiation studies under simultaneous hypoxia in vitro

(2018) Olli Metsälä et al.   Radiation Oncology

Short-term physiological hypoxia potentiates the therapeutic function of mesenchymal stem cells

(2018) Ben Antebi et al.   Stem Cell Research & Therapy

Aging of mesenchymal stem cells: Implication in regenerative medicine

(2018) Yueh-Hsun Kevin Yang   Regenerative Therapy

Effect of hypoxia on the proliferation of porcine bone marrow-derived mesenchymal stem cells and adipose-derived mesenchymal stem cells in 2- and 3-dimensional culture

(2017) Egon Burian et al.   JOURNAL OF CRANIO-MAXILLOFACIAL SURGERY

Hypoxia suppresses osteogenesis of bone mesenchymal stem cells via the extracellular signal-regulated 1/2 and p38-mitogen activated protein kinase signaling pathways

(2017) Peng Zhang et al.   Molecular Medicine Reports

Hypoxia for Mesenchymal Stem Cell Expansion and Differentiation: The Best Way for Enhancing TGFß-Induced Chondrogenesis and Preventing Calcifications in Alginate Beads

(2017) Christel Henrionnet et al.   TISSUE ENGINEERING PART A

A decade of progress in tissue engineering

(2016) Ali Khademhosseini et al.   Nature Protocols

The Influence of Aging on the Regenerative Potential of Human Adipose Derived Mesenchymal Stem Cells

(2016) Monika Marędziak et al.   Stem Cells International

Hypoxia and free radicals: Role in tumor progression and the use of engineering-based platforms to address these relationships

(2015) Abigail Hielscher et al.   FREE RADICAL BIOLOGY AND MEDICINE

The Role of Reactive Oxygen Species in Mesenchymal Stem Cell Adipogenic and Osteogenic Differentiation: A Review

(2015) Fatemeh Atashi et al.   STEM CELLS AND DEVELOPMENT

Hypoxia Regulates the Therapeutic Potential of Mesenchymal Stem Cells Through Enhanced Autophagy

(2015) Jiejie Liu et al.   International Journal of Lower Extremity Wounds

Do hypoxia/normoxia culturing conditions change the neuroregulatory profile of Wharton Jelly mesenchymal stem cell secretome?

(2015) Fábio G. Teixeira et al.   Stem Cell Research & Therapy

Hypoxic preconditioning potentiates the trophic effects of mesenchymal stem cells on co-cultured human primary hepatocytes

(2015) Harry H. Qin et al.   Stem Cell Research & Therapy

Wharton’s Jelly Derived Mesenchymal Stem Cells: Future of Regenerative Medicine? Recent Findings and Clinical Significance

(2015) Ilona Kalaszczynska et al.   Biomed Research International

Hypoxia Induces Autophagy of Bone Marrow-Derived Mesenchymal Stem Cells via Activation of ERK1/2

(2014) Junfang Wu et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

A comparative analysis of human mesenchymal stem cell response to hypoxia in vitro: Implications to translational strategies

(2014) Beatrice Dionigi et al.   JOURNAL OF PEDIATRIC SURGERY

Oxygen control with microfluidics

(2014) Martin D. Brennan et al.   LAB ON A CHIP

Mesenchymal stem cells and hypoxia: Where are we?

(2014) L.B. Buravkova et al.   MITOCHONDRION

Impact of Aging on the Regenerative Properties of Bone Marrow-, Muscle-, and Adipose-Derived Mesenchymal Stem/Stromal Cells

(2014) Olivia S. Beane et al.   PLoS One

Roles of Hypoxia During the Chondrogenic Differentiation of Mesenchymal Stem Cells

(2014) Jin Shang et al.   Current Stem Cell Research & Therapy

Human Bone Marrow-Derived Mesenchymal Stem Cells Display Enhanced Clonogenicity but Impaired Differentiation With Hypoxic Preconditioning

(2014) Lisa B. Boyette et al.   Stem Cells Translational Medicine

HIF-1α Confers Resistance to Induced Stress in Bone Marrow-derived Mesenchymal Stem Cells

(2013) Ali Asghar Kiani et al.   ARCHIVES OF MEDICAL RESEARCH

The role of hypoxia in stem cell potency and differentiation

(2013) Kate E Hawkins et al.   Regenerative Medicine

Hypoxic Culture Conditions as a Solution for Mesenchymal Stem Cell Based Regenerative Therapy

(2013) Nazmul Haque et al.   TheScientificWorldJOURNAL

Microfluidic isolation of highly pure embryonic stem cells using feeder-separated co-culture system

(2013) Qiushui Chen et al.   Scientific Reports

Molecular mechanism of hypoxia-induced chondrogenesis and its application in in vivo cartilage tissue engineering

(2012) Elise Duval et al.   BIOMATERIALS

Pre-culturing human adipose tissue mesenchymal stem cells under hypoxia increases their adipogenic and osteogenic differentiation potentials

(2012) M. G. Valorani et al.   CELL PROLIFERATION

Hypoxic preconditioning enhances the therapeutic potential of the secretome from cultured human mesenchymal stem cells in experimental traumatic brain injury

(2012) Ching-Ping Chang et al.   CLINICAL SCIENCE

Increased Proliferation and Analysis of Differential Gene Expression in Human Wharton's Jelly-derived Mesenchymal Stromal Cells under Hypoxia

(2012) Usha Nekanti et al.   International Journal of Biological Sciences

In vivo oxygen tension in human septal cartilage increases with age

(2012) Marsha S. Reuther et al.   LARYNGOSCOPE

Hypoxia mediated isolation and expansion enhances the chondrogenic capacity of bone marrow mesenchymal stromal cells

(2012) Adetola B Adesida et al.   Stem Cell Research & Therapy

Oxygen tension regulates the osteogenic, chondrogenic and endochondral phenotype of bone marrow derived mesenchymal stem cells

(2011) Eamon J. Sheehy et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Long term culture of mesenchymal stem cells in hypoxia promotes a genetic program maintaining their undifferentiated and multipotent status

(2011) Leticia Basciano et al.   BMC CELL BIOLOGY

Hypoxia inhibits the spontaneous calcification of bone marrow-derived mesenchymal stem cells

(2011) Yong-Can Huang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Hypoxia Inhibits Osteogenesis in Human Mesenchymal Stem Cells through Direct Regulation of RUNX2 by TWIST

(2011) Der-Chih Yang et al.   PLoS One

Hypoxic preconditioning induces the expression of prosurvival and proangiogenic markers in mesenchymal stem cells

(2010) Simi M. Chacko et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Low physiologic oxygen tensions reduce proliferation and differentiation of human multipotent mesenchymal stromal cells

(2010) Christina Holzwarth et al.   BMC CELL BIOLOGY

Hypoxia increases Sca-1/CD44 co-expression in murine mesenchymal stem cells and enhances their adipogenic differentiation potential

(2010) M. G. Valorani et al.   CELL AND TISSUE RESEARCH

Effects of hypoxic culture conditions on umbilical cord-derived human mesenchymal stem cells

(2010) Antonina Lavrentieva et al.   Cell Communication and Signaling

Differential roles of hypoxia inducible factor subunits in multipotential stromal cells under hypoxic condition

(2010) Kenichi Tamama et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Phenotypic differences during the osteogenic differentiation of single cell-derived clones isolated from human lipoaspirates

(2010) Beatriz Paredes et al.   Journal of Tissue Engineering and Regenerative Medicine

Improved survival of mesenchymal stromal cell after hypoxia preconditioning: Role of oxidative stress

(2010) Karen M. Peterson et al.   LIFE SCIENCES

Low Oxygen Tension and Synthetic Nanogratings Improve the Uniformity and Stemness of Human Mesenchymal Stem Cell Layer

(2010) Feng Zhao et al.   MOLECULAR THERAPY

Human Mesenchymal Stem Cells Efficiently Manage Oxidative Stress

(2010) Araceli Valle-Prieto et al.   STEM CELLS AND DEVELOPMENT

Mesenchymal stem cells cultured under hypoxia escape from senescence via down-regulation of p16 and extracellular signal regulated kinase

(2009) Yonghui Jin et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Hypoxia and stem cell-based engineering of mesenchymal tissues

(2009) Teng Ma et al.   BIOTECHNOLOGY PROGRESS

Impact of oxygen environment on mesenchymal stem cell expansion and chondrogenic differentiation

(2009) A. Krinner et al.   CELL PROLIFERATION

The Role of Hypoxia in Stem Cell Differentiation and Therapeutics

(2009) Hamid Abdollahi et al.   JOURNAL OF SURGICAL RESEARCH

Hypoxic Preconditioning of Human Mesenchymal Stem Cells Overcomes Hypoxia-Induced Inhibition of Osteogenic Differentiation

(2009) Elias Volkmer et al.   TISSUE ENGINEERING PART A

The Role of Hypoxia in Bone Marrow–Derived Mesenchymal Stem Cells: Considerations for Regenerative Medicine Approaches

(2009) Ruud Das et al.   TISSUE ENGINEERING PART B-REVIEWS

Dynamic Three-Dimensional Culture Methods Enhance Mesenchymal Stem Cell Properties and Increase Therapeutic Potential

(2009) Jessica E. Frith et al.   TISSUE ENGINEERING PART C-METHODS

Mitochondrial generation of free radicals and hypoxic signaling

(2009) Robert O. Poyton et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

The role of oxygen availability in embryonic development and stem cell function

(2008) M. Celeste Simon et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY