c-MYC-induced long noncoding RNA MEG3 aggravates kidney ischemia–reperfusion injury through activating mitophagy by upregulation of RTKN to trigger the Wnt/β-catenin pathway

The Biomarker TCONS_00016233 Drives Septic AKI by Targeting the miR-22-3p/AIFM1 Signaling Axis

(2020) Pan Zhang et al.   Molecular Therapy-Nucleic Acids

lncRNA RMST Suppressed GBM Cell Mitophagy through Enhancing FUS SUMOylation

(2020) Changhong Liu et al.   Molecular Therapy-Nucleic Acids

Downregulation of XIST ameliorates acute kidney injury by sponging miR‐142‐5p and targeting PDCD4

(2020) Bo Tang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Increasing Fatty Acid Oxidation Prevents High Fat Diet Induced Cardiomyopathy through Regulating Parkin Mediated Mitophagy

(2020) Dan Shao et al.   CIRCULATION

Role of Long Noncoding RNA MEG3/MiR-378/GRB2 Axis in Neuronal Autophagy and Neurological Functional Impairment in Ischemic Stroke

(2020) Hong-Cheng Luo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HIF-1α-BNIP3-mediated mitophagy in tubular cells protects against renal ischemia/reperfusion injury

(2020) Zong-Jie Fu et al.   Redox Biology

Exosomal miR-1910-3p promotes proliferation, metastasis, and autophagy of breast cancer cells by targeting MTMR3 and activating the NF-κB signaling pathway

(2020) Bo Wang et al.   CANCER LETTERS

The mTOR/ULK1 signaling pathway mediates the autophagy-promoting and osteogenic effects of dicalcium silicate nanoparticles

(2020) Wang Ruolan et al.   JOURNAL OF NANOBIOTECHNOLOGY

Single cell analysis reveals the involvement of the long non-coding RNA Pvt1 in the modulation of muscle atrophy and mitochondrial network

(2019) Enrico Alessio et al.   NUCLEIC ACIDS RESEARCH

miRNA‐145‐5p induces apoptosis after ischemia‐reperfusion by targeting dual specificity phosphatase 6

(2019) Gang Wu et al.   JOURNAL OF CELLULAR PHYSIOLOGY

LINC00520 targeting miR-27b-3p regulates OSMR expression level to promote acute kidney injury development through the PI3K/AKT signaling pathway

(2019) Xinghan Tian et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Repression of long non-coding RNA MEG3 restores nerve growth and alleviates neurological impairment after cerebral ischemia-reperfusion injury in a rat model

(2019) Dong You et al.   BIOMEDICINE & PHARMACOTHERAPY

Advanced oxidation protein products promote lipotoxicity and tubulointerstitial fibrosis via CD36/β-catenin pathway in diabetic nephropathy

(2019) Xiao Li et al.   ANTIOXIDANTS & REDOX SIGNALING

Attenuation of ST-segment elevation after ischemic conditioning maneuvers reflects cardioprotection online

(2019) Georgios Amanakis et al.   BASIC RESEARCH IN CARDIOLOGY

Mitochondria in Sepsis-Induced AKI

(2019) Jian Sun et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Non-coding RNA-Associated-ceRNA Networks in a New Contrast-induced Acute Kidney Injury Rat Model

(2019) Wei Cheng et al.   Molecular Therapy-Nucleic Acids

Long non-coding RNA-MEG3 contributes to myocardial ischemia-reperfusion injury through suppression of miR-7-5p expression

(2019) Liyuan Zou et al.   BIOSCIENCE REPORTS

LncRNA MEG3 inhibits cell proliferation and induces apoptosis in laryngeal cancer via miR‐23a/APAF‐1 axis

(2019) Xiaowen Zhang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

LncRNA MEG3 contributes to adenosine‐induced cytotoxicity in hepatoma HepG2 cells by downregulated ILF3 and autophagy inhibition via regulation PI3K‐AKT‐mTOR and beclin‐1 signaling pathway

(2019) Zejin Pu et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

FOXP1-induced lncRNA CLRN1-AS1 acts as a tumor suppressor in pituitary prolactinoma by repressing the autophagy via inactivating Wnt/β-catenin signaling pathway

(2019) Chao Wang et al.   Cell Death & Disease

MYC-driven regulation of long non-coding RNA profiles in breast cancer cells

(2019) Pervin Elvan Tokgun et al.   GENE

A Novel MYCN-Specific Antigene Oligonucleotide Deregulates Mitochondria and Inhibits Tumor Growth in MYCN-Amplified Neuroblastoma

(2019) Luca Montemurro et al.   CANCER RESEARCH

Acute kidney injury

(2019) Claudio Ronco et al.   LANCET

Long non-coding RNA MEG3 promotes cerebral ischemia-reperfusion injury through increasing pyroptosis by targeting miR-485/AIM2 axis

(2019) Ji Liang et al.   EXPERIMENTAL NEUROLOGY

Fundc1-dependent mitophagy is obligatory to ischemic preconditioning-conferred renoprotection in ischemic AKI via suppression of Drp1-mediated mitochondrial fission

(2019) Jin Wang et al.   Redox Biology

Autophagy promotes metastasis and glycolysis by upregulating MCT1 expression and Wnt/β-catenin signaling pathway activation in hepatocellular carcinoma cells

(2018) Qing Fan et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Long non-coding RNA HULC interacts with miR-613 to regulate colon cancer growth and metastasis through targeting RTKN

(2018) Yan Dong et al.   BIOMEDICINE & PHARMACOTHERAPY

LncRNA MEG3 inhibits the progression of prostate cancer by modulating miR-9-5p/QKI-5 axis

(2018) Meng Wu et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Long noncoding RNA MEG3 inhibits proliferation and migration but induces autophagy by regulation of Sirt7 and PI3K/AKT/mTOR pathway in glioma cells

(2018) Dong-Hui Xu et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Noncoding RNAs in acute kidney injury

(2018) Timo Brandenburger et al.   KIDNEY INTERNATIONAL

The mechanism of long non-coding RNA MEG3 for hepatic ischemia-reperfusion: Mediated by miR-34a/Nrf2 signaling pathway

(2017) Xinli Huang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

(Pro)renin Receptor Is an Amplifier of Wnt/ β -Catenin Signaling in Kidney Injury and Fibrosis

(2017) Zhen Li et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Long non-coding RNA MEG3 functions as a competing endogenous RNA to regulate ischemic neuronal death by targeting miR-21/PDCD4 signaling pathway

(2017) Honglin Yan et al.   Cell Death & Disease

miR-145-5p/Nurr1/TNF-α Signaling-Induced Microglia Activation Regulates Neuron Injury of Acute Cerebral Ischemic/Reperfusion in Rats

(2017) Xuemei Xie et al.   Frontiers in Molecular Neuroscience

Inhibition of rhotekin exhibits antitumor effects in lung cancer cells

(2016) WEIZHEN ZHANG et al.   ONCOLOGY REPORTS

MicroRNA-152 inhibits tumor cell growth by directly targeting RTKN in hepatocellular carcinoma

(2016) Jiejing Zhou et al.   ONCOLOGY REPORTS

Mitochondria-Targeted Antioxidants: Future Perspectives in Kidney Ischemia Reperfusion Injury

(2016) Aleksandra Kezic et al.   Oxidative Medicine and Cellular Longevity

Sustained Activation of Wnt/ -Catenin Signaling Drives AKI to CKD Progression

(2015) L. Xiao et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

MicroRNA21 promotes interstitial fibrosis via targeting DDAH1: a potential role in renal fibrosis

(2015) Xiu-Juan Liu et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

A Network Based Method for Analysis of lncRNA-Disease Associations and Prediction of lncRNAs Implicated in Diseases

(2014) Xiaofei Yang et al.   PLoS One

Autophagy plays a critical role in kidney tubule maintenance, aging and ischemia-reperfusion injury

(2012) Shuya Liu et al.   Autophagy

A ceRNA Hypothesis: The Rosetta Stone of a Hidden RNA Language?

(2011) Leonardo Salmena et al.   CELL

Biological modulation of renal ischemia–reperfusion injury

(2010) Maarten GJ Snoeijs et al.   Current Opinion in Organ Transplantation