Neoagarotetraose extends the lifespan of Caenorhabditis elegans through AMPK mediated signaling pathways and activation of autophagy

Protecting the Aging Genome

(2020) Michael A. Petr et al.   TRENDS IN CELL BIOLOGY

Is Rapamycin a Dietary Restriction Mimetic?

(2019) Archana Unnikrishnan et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Caloric Restriction Mimetics against Age-Associated Disease: Targets, Mechanisms, and Therapeutic Potential

(2019) Frank Madeo et al.   Cell Metabolism

Diet restriction-induced healthy aging is mediated through the immune signaling component ZIP-2 in Caenorhabditis elegans

(2019) Jeong-Hoon Hahm et al.   AGING CELL

Biochemical characterization of a truncated β-agarase from Microbulbifer sp. suitable for efficient production of neoagarotetraose

(2019) Junwen Ma et al.   PROCESS BIOCHEMISTRY

Anti-ageing and antioxidant effects of sulfate oligosaccharides from green algae Ulva lactuca and Enteromorpha prolifera in SAMP8 mice

(2019) Xiao-yan Liu et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Anti-aging Effect of Agar Oligosaccharide on Male Drosophila melanogaster and its Preliminary Mechanism

(2019) Ma et al.   Marine Drugs

Anti-Aging Effect of Chitosan Oligosaccharide on d-Galactose-Induced Subacute Aging in Mice

(2018) Song-Zhi Kong et al.   Marine Drugs

Quantification of Neoagaro-Oligosaccharide Production through Enzymatic Hydrolysis and Its Anti-Oxidant Activities

(2018) Shu-Ying Xu et al.   MOLECULES

Autophagy as a promoter of longevity: insights from model organisms

(2018) Malene Hansen et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Panax notoginseng polysaccharide increases stress resistance and extends lifespan in Caenorhabditis elegans

(2018) Shiling Feng et al.   Journal of Functional Foods

A salicylic acid derivative extends the lifespan of Caenorhabditis elegans by activating autophagy and the mitochondrial unfolded protein response

(2018) Mehrnaz Shamalnasab et al.   AGING CELL

β-Agarase immobilized on tannic acid-modified Fe3O4 nanoparticles for efficient preparation of bioactive neoagaro-oligosaccharide

(2018) Qiong Xiao et al.   FOOD CHEMISTRY

Beneficial Effects of Marine Algae-Derived Carbohydrates for Skin Health

(2018) Ji Kim et al.   Marine Drugs

Sesamin extends lifespan through pathways related to dietary restriction in Caenorhabditis elegans

(2017) Yumiko Nakatani et al.   EUROPEAN JOURNAL OF NUTRITION

Purification, in vitro antioxidant and in vivo anti-aging activities of exopolysaccharides by Agrocybe cylindracea

(2017) Huajie Zhao et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Anti-Obesity and Anti-Diabetic Effect of Neoagarooligosaccharides on High-Fat Diet-Induced Obesity in Mice

(2017) Sun Joo Hong et al.   Marine Drugs

Neoagarotetraose protects mice against intense exercise-induced fatigue damage by modulating gut microbial composition and function

(2017) Na Zhang et al.   MOLECULAR NUTRITION & FOOD RESEARCH

EpimediumPolysaccharide Alleviates Polyglutamine-Induced Neurotoxicity inCaenorhabditis elegansby Reducing Oxidative Stress

(2017) Yanxia Xiang et al.   REJUVENATION RESEARCH

Glycogen controls Caenorhabditis elegans lifespan and resistance to oxidative stress

(2017) Ivan Gusarov et al.   Nature Communications

Neoagaro-oligosaccharide monomers inhibit inflammation in LPS-stimulated macrophages through suppression of MAPK and NF-κB pathways

(2017) Wei Wang et al.   Scientific Reports

Anti-ageing active ingredients from herbs and nutraceuticals used in traditional Chinese medicine: pharmacological mechanisms and implications for drug discovery

(2016) Chun-Yan Shen et al.   BRITISH JOURNAL OF PHARMACOLOGY

The Mechanistic Target of Rapamycin: The Grand ConducTOR of Metabolism and Aging

(2016) Brian K. Kennedy et al.   Cell Metabolism

Antioxidant and neuroprotective effects of Dictyophora indusiata polysaccharide in Caenorhabditis elegans

(2016) Ju Zhang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Does Longer Lifespan Mean Longer Healthspan?

(2016) Malene Hansen et al.   TRENDS IN CELL BIOLOGY

Long live FOXO: unraveling the role of FOXO proteins in aging and longevity

(2015) Rute Martins et al.   AGING CELL

mTOR signaling in cellular and organismal energetics

(2015) Verena Albert et al.   CURRENT OPINION IN CELL BIOLOGY

Cranberry Extract Standardized for Proanthocyanidins Alleviates β-Amyloid Peptide Toxicity by Improving Proteostasis Through HSF-1 inCaenorhabditis elegansModel of Alzheimer’s Disease

(2015) Hong Guo et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Anti-aging effect of polysaccharide from Bletilla striata on nematode Caenorhabditis elegans

(2015) Xiaoyu Ding et al.   Pharmacognosy Magazine

Caloric restriction mimetics: natural/physiological pharmacological autophagy inducers

(2014) Guillermo Mariño et al.   Autophagy

AMPK at the Nexus of Energetics and Aging

(2014) Kristopher Burkewitz et al.   Cell Metabolism

A fucose containing polymer-rich fraction from the brown alga Ascophyllum nodosum mediates lifespan increase and thermal-tolerance in Caenorhabditis elegans, by differential effects on gene and protein expression

(2013) Saveetha Kandasamy et al.   Food & Function

p70S6 Kinase Phosphorylates AMPK on Serine 491 to Mediate Leptin's Effect on Food Intake

(2012) Yossi Dagon et al.   Cell Metabolism

Tasco®, a Product of Ascophyllum nodosum, Imparts Thermal Stress Tolerance in Caenorhabditis elegans

(2011) Saveetha Kandasamy et al.   Marine Drugs

Agarase: Review of Major Sources, Categories, Purification Method, Enzyme Characteristics and Applications

(2010) Xiao Ting Fu et al.   Marine Drugs

Extending Healthy Life Span--From Yeast to Humans

(2010) L. Fontana et al.   SCIENCE

Direct Inhibition of the Longevity-Promoting Factor SKN-1 by Insulin-like Signaling in C. elegans

(2008) Jennifer M.A. Tullet et al.   CELL