Hot melt extrusion: An emerging manufacturing method for slow and sustained protein delivery
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Title
Hot melt extrusion: An emerging manufacturing method for slow and sustained protein delivery
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Keywords
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Journal
Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology
Volume -, Issue -, Pages -
Publisher
Wiley
Online
2021-03-11
DOI
10.1002/wnan.1712
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Note: Only part of the references are listed.- Cryopolymerization of 1,2-Dithiolanes for the Facile and Reversible Grafting-from Synthesis of Protein–Polydisulfide Conjugates
- (2020) Jianhua Lu et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- All wrapped up: Stabilization of enzymes within single enzyme nanoparticles
- (2019) Robert Chapman et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Baroplastics with Robust Mechanical Properties and Reserved Processability through Hydrogen-Bonded Interactions
- (2019) Zhi Lv et al. ACS Applied Materials & Interfaces
- Recent Perspectives in Hot Melt Extrusion-Based Polymeric Formulations for Drug Delivery: Applications and Innovations
- (2019) Yangmei Ren et al. AAPS PHARMSCITECH
- Self-powered, on-demand transdermal drug delivery system driven by triboelectric nanogenerator
- (2019) Qingling Ouyang et al. Nano Energy
- Direct powder extrusion 3D printing: Fabrication of drug products using a novel single-step process
- (2019) Alvaro Goyanes et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Design and fabrication of a low-cost pilot-scale melt-processing system
- (2019) David M. Wirth et al. POLYMER
- Micro/nanofabrication of brittle hydrogels using 3D printed soft ultrafine fiber molds for damage-free demolding
- (2019) Shang Lv et al. Biofabrication
- Polycation-telodendrimer nanocomplexes for intracellular protein delivery
- (2018) Xu Wang et al. COLLOIDS AND SURFACES B-BIOINTERFACES
- Additive manufacturing (3D printing): A review of materials, methods, applications and challenges
- (2018) Tuan D. Ngo et al. COMPOSITES PART B-ENGINEERING
- Improving release completeness from PLGA-based implants for the acid-labile model protein ovalbumin
- (2018) Luisa Duque et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Selection of Solid-State Plasticizers as Processing Aids for Hot-Melt Extrusion
- (2018) Dipen Desai et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Hot Melt Extrusion as Solvent-Free Technique for a Continuous Manufacturing of Drug-Loaded Mesoporous Silica
- (2018) Natalja Genina et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- 3D Printing Pharmaceuticals: Drug Development to Frontline Care
- (2018) Sarah J. Trenfield et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Continuous manufacturing of co-crystals: challenges and prospects
- (2018) Rahul B. Chavan et al. Drug Delivery and Translational Research
- Drying Technologies for the Stability and Bioavailability of Biopharmaceuticals
- (2018) Fakhrossadat Emami et al. Pharmaceutics
- Poly(2‐oxazoline)s terminated with 2,2′‐imino diacetic acid form noncovalent polymer–enzyme conjugates that are highly active in organic solvents
- (2018) Montasser Hijazi et al. BIOTECHNOLOGY AND BIOENGINEERING
- Trehalose Limits Fragment Antibody Aggregation and Influences Charge Variant Formation in Spray-Dried Formulations at Elevated Temperatures
- (2018) Karthikan Rajagopal et al. MOLECULAR PHARMACEUTICS
- Biopharmaceutical benchmarks 2018
- (2018) Gary Walsh NATURE BIOTECHNOLOGY
- Implantable Polymeric Drug Delivery Devices: Classification, Manufacture, Materials, and Clinical Applications
- (2018) Sarah Stewart et al. Polymers
- Identifying critical process steps to protein stability during spray drying using a vibrating mesh or a two-fluid nozzle
- (2018) Niels Grasmeijer et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Milling solid proteins to enhance activity after melt-encapsulation
- (2017) Parker W. Lee et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- 3D printed oral solid dosage forms containing hydrochlorothiazide for controlled drug delivery
- (2017) Christos I. Gioumouxouzis et al. JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
- Enzyme stabilization via computationally guided protein stapling
- (2017) Eric J. Moore et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Synthesis, properties and biomedical applications of hydrolytically degradable materials based on aliphatic polyesters and polycarbonates
- (2017) Ruairí P. Brannigan et al. Biomaterials Science
- The Development of a Melt-Extruded Shellac Carrier for the Targeted Delivery of Probiotics to the Colon
- (2017) Noel Gately et al. Pharmaceutics
- Escherichia coli-derived virus-like particles in vaccine development
- (2017) Xiaofen Huang et al. npj Vaccines
- Hot Melt Extrusion for Sustained Protein Release: Matrix Erosion and In Vitro Release of PLGA-Based Implants
- (2016) Anne Cossé et al. AAPS PHARMSCITECH
- Nanosizing a Metal–Organic Framework Enzyme Carrier for Accelerating Nerve Agent Hydrolysis
- (2016) Peng Li et al. ACS Nano
- Low-Temperature Processable Block Copolymers That Preserve the Function of Blended Proteins
- (2016) Yasuhiko Iwasaki et al. BIOMACROMOLECULES
- “Graft-to” Protein/Polymer Conjugates Using Polynorbornene Block Copolymers
- (2016) Sergey A. Isarov et al. BIOMACROMOLECULES
- Investigating the Impact of Polymer Functional Groups on the Stability and Activity of Lysozyme–Polymer Conjugates
- (2016) Melissa Lucius et al. BIOMACROMOLECULES
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- (2016) Hiren G. Moradiya et al. CRYSTAL GROWTH & DESIGN
- Delivery of Therapeutic Proteins: Challenges and Strategies
- (2016) Kanwal Rehman et al. CURRENT DRUG TARGETS
- Fused-filament 3D printing of drug products: Microstructure analysis and drug release characteristics of PVA-based caplets
- (2016) Alvaro Goyanes et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Polyanions effectively prevent protein conjugation and activity loss during hydrogel cross-linking
- (2016) Manuel Gregoritza et al. JOURNAL OF CONTROLLED RELEASE
- Materials technology in drug eluting balloons: Current and future perspectives
- (2016) Gordon Minru Xiong et al. JOURNAL OF CONTROLLED RELEASE
- Nanotechnology for protein delivery: Overview and perspectives
- (2016) Mikyung Yu et al. JOURNAL OF CONTROLLED RELEASE
- Hot melt extrusion as an approach to improve solubility, permeability and oral absorption of a psychoactive natural product, piperine
- (2016) Eman A. Ashour et al. JOURNAL OF PHARMACY AND PHARMACOLOGY
- Dual Functionalized Bacteriophage Qβ as a Photocaged Drug Carrier
- (2016) Zhuo Chen et al. Small
- Three-dimensional printing: review of application in medicine and hepatic surgery
- (2016) Yao Rui et al. Cancer Biology & Medicine
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- (2015) Hemlata Patil et al. AAPS PHARMSCITECH
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- (2015) Marcus T. Cicerone et al. ADVANCED DRUG DELIVERY REVIEWS
- Therapeutic outcomes, assessments, risk factors and mitigation efforts of immunogenicity of therapeutic protein products
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- A flexible-dose dispenser for immediate and extended release 3D printed tablets
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- Contribution of hot-melt extrusion technology to advance drug delivery in the 21st century
- (2015) Roshan V. Tiwari et al. Expert Opinion on Drug Delivery
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- Downstream processing of polymer-based amorphous solid dispersions to generate tablet formulations
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- PEGylation to Improve Protein Stability During Melt Processing
- (2015) Parker Lee et al. MACROMOLECULAR BIOSCIENCE
- Advanced protein formulations
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- Active drug release systems: current status, applications and perspectives
- (2014) Maxim V Kiryukhin CURRENT OPINION IN PHARMACOLOGY
- Hot-melt co-extrusion for the production of fixed-dose combination products with a controlled release ethylcellulose matrix core
- (2014) A.-K. Vynckier et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Effect of storage temperature and antibiotic impregnation on the quantity of bone morphogenetic protein seven in human bone grafts
- (2014) Alexander Wurm et al. INTERNATIONAL ORTHOPAEDICS
- Low temperature extruded implants based on novel hydrophilic multiblock copolymer for long-term protein delivery
- (2013) Milica Stanković et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Co-extrusion as manufacturing technique for multilayer mini-matrices with dual drug release
- (2013) L. Dierickx et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Is the pre-Tg DSC endotherm observed with solid state proteins associated with the protein internal dynamics? Investigation of bovine serum albumin by solid state hydrogen/deuterium exchange
- (2013) Masayasu Mizuno et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- PAT tools for the control of co-extrusion implants manufacturing process
- (2013) Fabrice Krier et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Trehalose Limits BSA Aggregation in Spray-Dried Formulations at High Temperatures: Implications in Preparing Polymer Implants for Long-Term Protein Delivery
- (2013) Karthikan Rajagopal et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Introduction to protein crystallization
- (2013) Alexander McPherson et al. Acta Crystallographica Section F-Structural Biology Communications
- Prediction of quality attributes of continuously produced granules using complementary pat tools
- (2012) Margot Fonteyne et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Protein release from poly(lactide-co-glycolide) implants prepared by hot-melt extrusion: Thioester formation as a reason for incomplete release
- (2012) Zahra Ghalanbor et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Well-defined cross-linked antioxidant nanozymes for treatment of ischemic brain injury
- (2012) Devika S. Manickam et al. JOURNAL OF CONTROLLED RELEASE
- Hartree analysis of χ for a pressure-responsive diblock copolymer: Temperature-pressure superposition
- (2012) Junhan Cho MACROMOLECULAR RESEARCH
- Low-Temperature Processable Degradable Polyesters
- (2012) Ikuo Taniguchi et al. MACROMOLECULES
- Effects of Thermal Denaturation on the Solid-State Structure and Molecular Mobility of Glycinin
- (2011) Mickey G. Huson et al. BIOMACROMOLECULES
- Applications of viral nanoparticles in medicine
- (2011) Ibrahim Yildiz et al. CURRENT OPINION IN BIOTECHNOLOGY
- Biomedical applications of biodegradable polymers
- (2011) Bret D. Ulery et al. JOURNAL OF POLYMER SCIENCE PART B-POLYMER PHYSICS
- FDA-approved poly(ethylene glycol)–protein conjugate drugs
- (2011) Steevens N. S. Alconcel et al. Polymer Chemistry
- Volume Exclusion and Soft Interaction Effects on Protein Stability under Crowded Conditions
- (2010) Andrew C. Miklos et al. BIOCHEMISTRY
- Technosphere® Insulin
- (2010) Joshua J. Neumiller et al. BIODRUGS
- Ethylene vinyl acetate as matrix for oral sustained release dosage forms produced via hot-melt extrusion
- (2010) A. Almeida et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Drug release kinetics and transport mechanisms of non-degradable and degradable polymeric delivery systems
- (2010) Yao Fu et al. Expert Opinion on Drug Delivery
- Biochemical and biophysical characterization of lysozyme modified by PEGylation
- (2010) Débora da Silva Freitas et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Nano spray drying: A novel method for preparing protein nanoparticles for protein therapy
- (2010) Sie Huey Lee et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Cocrystalization and Simultaneous Agglomeration Using Hot Melt Extrusion
- (2010) Ravindra S. Dhumal et al. PHARMACEUTICAL RESEARCH
- PLGA Erosion: Solubility- or Diffusion-Controlled?
- (2010) Martin Körber PHARMACEUTICAL RESEARCH
- Polymers for Drug Delivery Systems
- (2010) William B. Liechty et al. Annual Review of Chemical and Biomolecular Engineering
- Examining the efficacy, safety, and patient acceptability of the etonogestrel implantable contraceptive
- (2010) Heather Hohmann Patient Preference and Adherence
- Viruses and their potential in bioimaging and biosensing applications
- (2009) Kai Li et al. ANALYST
- Hard and soft micro- and nanofabrication: An integrated approach to hydrogel-based biosensing and drug delivery
- (2009) Ronald A. Siegel et al. JOURNAL OF CONTROLLED RELEASE
- Mechanisms of protein stabilization in the solid state
- (2009) Liuquan (Lucy) Chang et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Synthesis and bioactivity of poly(HPMA)–lysozyme conjugates: the use of novel thiazolidine-2-thione coupling chemistry
- (2009) Lei Tao et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Improved Lysozyme Stability and Release Properties of Poly(lactide-co-glycolide) Implants Prepared by Hot-Melt Extrusion
- (2009) Zahra Ghalanbor et al. PHARMACEUTICAL RESEARCH
- Effect of trehalose on protein structure
- (2009) Nishant Kumar Jain et al. PROTEIN SCIENCE
- Guiding Protein Aggregation with Macromolecular Crowding†
- (2008) Larissa A. Munishkina et al. BIOCHEMISTRY
- Solid state stability of proteins III: Calorimetric (DSC) and spectroscopic (FTIR) characterization of thermal denaturation in freeze dried human growth hormone (hGH)
- (2008) Michael J. Pikal et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Secondary Structural Change of Bovine Serum Albumin in Thermal Denaturation up to 130 °C and Protective Effect of Sodium Dodecyl Sulfate on the Change
- (2008) Yoshiko Moriyama et al. JOURNAL OF PHYSICAL CHEMISTRY B
- Transdermal drug delivery
- (2008) Mark R Prausnitz et al. NATURE BIOTECHNOLOGY
- Pharmaceutical Quality by Design: Product and Process Development, Understanding, and Control
- (2008) Lawrence X. Yu PHARMACEUTICAL RESEARCH
- Protein therapeutics: a summary and pharmacological classification
- (2007) Benjamin Leader et al. NATURE REVIEWS DRUG DISCOVERY
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