The Roles of T cells in Bladder Pathologies

Introducing a novel experimental model of bladder transplantation in mice

(2020) Jun Wang et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Interstitial cystitis/bladder pain syndrome: The evolving landscape, animal models and future perspectives

(2020) Yoshiyuki Akiyama et al.   INTERNATIONAL JOURNAL OF UROLOGY

A highly polarized TH2 bladder response to infection promotes epithelial repair at the expense of preventing new infections

(2020) Jianxuan Wu et al.   NATURE IMMUNOLOGY

Inhibition of Histone Deacetylase (HDAC) Enhances Checkpoint Blockade Efficacy by Rendering Bladder Cancer Cells Visible for T Cell-Mediated Destruction

(2020) Brianna Burke et al.   Frontiers in Oncology

Intratumoral CD4+ T Cells Mediate Anti-tumor Cytotoxicity in Human Bladder Cancer

(2020) David Y. Oh et al.   CELL

Bioinformatics Approach for Identifying Novel Biomarkers and Their Signaling Pathways Involved in Interstitial Cystitis/Bladder Pain Syndrome with Hunner Lesion

(2020) Subbroto Kumar Saha et al.   Journal of Clinical Medicine

Restriction of chronic Escherichia coli urinary tract infection depends upon T cell‐derived interleukin‐17, a deficiency of which predisposes to flagella‐driven bacterial persistence

(2020) Michelle N. Chamoun et al.   FASEB JOURNAL

Cancer statistics, 2019

(2019) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Intravesical Ty21a Vaccine Promotes Dendritic Cells and T Cell–Mediated Tumor Regression in the MB49 Bladder Cancer Model

(2019) Sonia Domingos-Pereira et al.   Cancer Immunology Research

Sphingosine 1 phosphate receptor-1 (S1P1) promotes tumor-associated regulatory T cell expansion: leading to poor survival in bladder cancer

(2019) Yi-Na Liu et al.   Cell Death & Disease

Disruption of CTLA-4 expression on peripheral blood CD8 + T cell enhances anti-tumor efficacy in bladder cancer

(2019) Wei Zhang et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Pathophysiology of interstitial cystitis

(2019) Lori A Birder   INTERNATIONAL JOURNAL OF UROLOGY

CCR4 Blockade Depletes Regulatory T Cells and Prolongs Survival in a Canine Model of Bladder Cancer

(2019) Shingo Maeda et al.   Cancer Immunology Research

Adaptive Immune Resistance to Intravesical BCG in Non-Muscle Invasive Bladder Cancer: Implications for Prospective BCG Unresponsive Trials

(2019) Max Kates et al.   CLINICAL CANCER RESEARCH

Antibody-mediated targeting of TNFR2 activates CD8+ T cells in mice and promotes antitumor immunity

(2019) Eric M. Tam et al.   Science Translational Medicine

Culturing of female bladder bacteria reveals an interconnected urogenital microbiota

(2018) Krystal Thomas-White et al.   Nature Communications

Cross-reactivity of HIV vaccine responses and the microbiome

(2018) Wilton B. Williams et al.   Current Opinion in HIV and AIDS

Interferon-Gamma at the Crossroads of Tumor Immune Surveillance or Evasion

(2018) Flávia Castro et al.   Frontiers in Immunology

CD19+ tumor-infiltrating B-cells prime CD4+ T-cell immunity and predict platinum-based chemotherapy efficacy in muscle-invasive bladder cancer

(2018) Qi Jiang et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Epidemiology of Bladder Cancer: A Systematic Review and Contemporary Update of Risk Factors in 2018

(2018) Marcus George Kwesi Cumberbatch et al.   EUROPEAN UROLOGY

Contribution of regulatory T cells to cancer: A review

(2018) Masoud Najafi et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Professional and ‘Amateur’ Antigen-Presenting Cells In Type 2 Immunity

(2018) Martijn J. Schuijs et al.   TRENDS IN IMMUNOLOGY

Preoperative Th1/Th2 and related cytokines: Prediction value in postoperative febrile UTI after ureteroscopy in patients with ureteral calculi

(2018) Zhen Li et al.   Advances in Clinical and Experimental Medicine

Host restriction of Escherichia coli recurrent urinary tract infection occurs in a bacterial strain-specific manner

(2018) Valerie P. O’Brien et al.   PLoS Pathogens

Single-cell analysis of tumors: Creating new value for molecular biomarker discovery of cancer stem cells and tumor-infiltrating immune cells

(2018) Ramin Radpour et al.   World Journal of Stem Cells

Circulating and Tissue-Resident CD4 + T Cells With Reactivity to Intestinal Microbiota Are Abundant in Healthy Individuals and Function Is Altered During Inflammation

(2017) Ahmed N. Hegazy et al.   GASTROENTEROLOGY

An Immunogenic Peptide, T2 Induces Interstitial Cystitis/Painful Bladder Syndrome: an Autoimmune Mouse Model for Interstitial Cystitis/Painful Bladder Syndrome

(2017) Li Zhang et al.   INFLAMMATION

ILC2-modulated T cell–to-MDSC balance is associated with bladder cancer recurrence

(2017) Mathieu F. Chevalier et al.   JOURNAL OF CLINICAL INVESTIGATION

Diagnostic value of urinary CXCL10 as a biomarker for predicting Hunner type interstitial cystitis

(2017) Aya Niimi et al.   NEUROUROLOGY AND URODYNAMICS

Mechanisms and Dynamics of T Cell-Mediated Cytotoxicity In Vivo

(2017) Stephan Halle et al.   TRENDS IN IMMUNOLOGY

Stromal Cell-Derived Factor 1 Mediates Immune Cell Attraction upon Urinary Tract Infection

(2017) Batya Isaacson et al.   Cell Reports

Intravesical BCG Induces CD4 + T-Cell Expansion in an Immune Competent Model of Bladder Cancer

(2017) Max Kates et al.   Cancer Immunology Research

Evidence for the Role of Mast Cells in Cystitis-Associated Lower Urinary Tract Dysfunction: A Multidisciplinary Approach to the Study of Chronic Pelvic Pain Research Network Animal Model Study

(2017) Xu Wang et al.   PLoS One

Intravesical Bacillus Calmette Guerin Combined with a Cancer Vaccine Increases Local T-Cell Responses in Non-muscle–Invasive Bladder Cancer Patients

(2016) Laurent Derré et al.   CLINICAL CANCER RESEARCH

Loss of Bladder Epithelium Induced by Cytolytic Mast Cell Granules

(2016) Hae Woong Choi et al.   IMMUNITY

Bladder cancer

(2016) Ashish M Kamat et al.   LANCET

The microbiota in adaptive immune homeostasis and disease

(2016) Kenya Honda et al.   NATURE

Increased CXCR3 Expression of Infiltrating Plasma Cells in Hunner Type Interstitial Cystitis

(2016) Yoshiyuki Akiyama et al.   Scientific Reports

A mucosal imprint left by prior Escherichia coli bladder infection sensitizes to recurrent disease

(2016) Valerie P. O'Brien et al.   Nature Microbiology

Decreased microbiota diversity associated with urinary tract infection in a trial of bacterial interference

(2015) Deborah Horwitz et al.   JOURNAL OF INFECTION

Urinary tract infections: epidemiology, mechanisms of infection and treatment options

(2015) Ana L. Flores-Mireles et al.   NATURE REVIEWS MICROBIOLOGY

The microbiome of the urinary tract—a role beyond infection

(2015) Samantha A. Whiteside et al.   Nature Reviews Urology

Overcoming T cell exhaustion in infection and cancer

(2015) Kristen E. Pauken et al.   TRENDS IN IMMUNOLOGY

Macrophages Subvert Adaptive Immunity to Urinary Tract Infection

(2015) Gabriela Mora-Bau et al.   PLoS Pathogens

γδ T Lymphocytes in the Diagnosis of Human T Cell Receptor Immunodeficiencies

(2015) Beatriz Garcillán et al.   Frontiers in Immunology

The Human Agonistic CD40 Antibody ADC-1013 Eradicates Bladder Tumors and Generates T-cell-Dependent Tumor Immunity

(2014) S. M. Mangsbo et al.   CLINICAL CANCER RESEARCH

MPDL3280A (anti-PD-L1) treatment leads to clinical activity in metastatic bladder cancer

(2014) Thomas Powles et al.   NATURE

T cell mediated immunity to influenza: mechanisms of viral control

(2014) Nicole L. La Gruta et al.   TRENDS IN IMMUNOLOGY

Mast Cell Interleukin-10 Drives Localized Tolerance in Chronic Bladder Infection

(2013) Cheryl Y. Chan et al.   IMMUNITY

Urinary Tract Infection Syndromes

(2013) Betsy Foxman   INFECTIOUS DISEASE CLINICS OF NORTH AMERICA

Antitumor T cell responses in bladder cancer are directed against a limited set of antigens and are modulated by regulatory T cells and routine treatment approaches

(2013) Thomas Horn et al.   INTERNATIONAL JOURNAL OF CANCER

Local immune response in bladder pain syndrome/interstitial cystitis ESSIC type 3C

(2013) Marianne Gamper et al.   INTERNATIONAL UROGYNECOLOGY JOURNAL

Comparative Biology of γδ T Cell Function in Humans, Mice, and Domestic Animals

(2013) Jeff Holderness et al.   Annual Review of Animal Biosciences

Evidence of Uncultivated Bacteria in the Adult Female Bladder

(2012) A. J. Wolfe et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Preexisting BCG-Specific T Cells Improve Intravesical Immunotherapy for Bladder Cancer

(2012) C. Biot et al.   Science Translational Medicine

BALB/c-Fcgr2b−/−Pdcd1−/− mouse expressing anti-urothelial antibody is a novel model of autoimmune cystitis

(2012) Yoshio Sugino et al.   Scientific Reports

A mouse model for interstitial cystitis/painful bladder syndrome based on APF inhibition of bladder epithelial repair: a pilot study

(2012) Susan Keay et al.   BMC Urology

Autoimmunity to Uroplakin II Causes Cystitis in Mice: A Novel Model of Interstitial Cystitis

(2011) Cengiz Z. Altuntas et al.   EUROPEAN UROLOGY

Urothelial antigen-specific CD4+ T cells function as direct effector cells and induce bladder autoimmune inflammation independent of CD8+ T cells

(2011) W Liu et al.   Mucosal Immunology

Helicobacter pylori Recurrence in Developed and Developing Countries: Meta-Analysis of 13C-Urea Breath Test Follow-Up after Eradication

(2010) Yaron Niv et al.   HELICOBACTER

The Innate Immune Response to Uropathogenic Escherichia coli Involves IL-17A in a Murine Model of Urinary Tract Infection

(2010) Kelsey E. Sivick et al.   JOURNAL OF IMMUNOLOGY

Taking off the brakes: T cell immunity in the liver

(2010) M. Kern et al.   TRENDS IN IMMUNOLOGY

RDP58 inhibits T cell-mediated bladder inflammation in an autoimmune cystitis model

(2008) Wujiang Liu et al.   JOURNAL OF AUTOIMMUNITY