New 2,9-disubstituted-1,10-phenanthroline derivatives with anticancer activity by selective targeting of telomeric G-quadruplex DNA

Design, Synthesis, Molecular Modelling and Anticancer Activities of New Fused Phenanthrolines

(2020) Cristina Maria Al Matarneh et al.   MOLECULES

Synthesis, molecular modelling and anticancer evaluation of new pyrrolo[1,2-b]pyridazine and pyrrolo[2,1-a]phthalazine derivatives

(2019) Lacramioara Popovici et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Human Telomeric G-Quadruplex Selective Fluoro-Isoquinolines Induce Apoptosis in Cancer Cells

(2018) Subhadip Maiti et al.   BIOCONJUGATE CHEMISTRY

Antimycobacterial activity of nitrogen heterocycles derivatives: 7-(pyridine-4-yl)-indolizine derivatives. Part VII8–12

(2017) Anda-Mihaela Olaru et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

New Disubstituted Quindoline Derivatives Inhibiting Burkitt’s Lymphoma Cell Proliferation by Impeding c-MYC Transcription

(2017) Hui-Yun Liu et al.   JOURNAL OF MEDICINAL CHEMISTRY

Development of squaraine based G-quadruplex ligands using click chemistry

(2017) Xin Zhang et al.   Scientific Reports

A Bis(methylpiperazinylstyryl)phenanthroline as a Fluorescent Ligand for G-Quadruplexes

(2016) Shangrong Wu et al.   CHEMISTRY-A EUROPEAN JOURNAL

Toward the Development of Specific G-Quadruplex Binders: Synthesis, Biophysical, and Biological Studies of New Hydrazone Derivatives

(2016) Jussara Amato et al.   JOURNAL OF MEDICINAL CHEMISTRY

A 4:1 stoichiometric binding and stabilization of mitoxantrone-parallel stranded G-quadruplex complex established by spectroscopy techniques

(2016) Tarikere Palakashan Pradeep et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY

Fluorometric determination of Simian virus 40 based on strand displacement amplification and triplex DNA using a molecular beacon probe with a guanine-rich fragment of the stem region

(2016) Yubin Li et al.   MICROCHIMICA ACTA

Atomic Force Microscopy and Voltammetric Investigation of Quadruplex Formation between a Triazole-Acridine Conjugate and Guanine-Containing Repeat DNA Sequences

(2015) Ana-Maria Chiorcea-Paquim et al.   ANALYTICAL CHEMISTRY

New indolizines with phenanthroline skeleton: Synthesis, structure, antimycobacterial and anticancer evaluation

(2015) Ramona Danac et al.   BIOORGANIC & MEDICINAL CHEMISTRY

New triazole appended tert-butyl calix[4]arene conjugates: synthesis, Hg2+ binding studies

(2015) Raluca Rusu et al.   TETRAHEDRON

Small-molecule quadruplex-targeted drug discovery

(2014) Stephan A. Ohnmacht et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Recent advances in small organic molecules as DNA intercalating agents: Synthesis, activity, and modeling

(2014) Antonio Rescifina et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Solution Structure of a G-quadruplex Bound to the Bisquinolinium Compound Phen-DC3

(2013) Wan Jun Chung et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Phenanthroline-2,9-bistriazoles as selective G-quadruplex ligands

(2013) Mads Corvinius Nielsen et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and binding studies of novel di-substituted phenanthroline compounds with genomic promoter and human telomeric DNA G-quadruplexes

(2013) Chunying Wei et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Tetrasubstituted Phenanthrolines as Highly Potent, Water-Soluble, and Selective G-Quadruplex Ligands

(2012) Anders Foller Larsen et al.   CHEMISTRY-A EUROPEAN JOURNAL

12-N-Methylated 5,6-dihydrobenzo[c]acridine derivatives: A new class of highly selective ligands for c-myc G-quadruplex DNA

(2012) Sheng-Rong Liao et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Molecular Dynamics Simulations of DNA/PEI Complexes: Effect of PEI Branching and Protonation State

(2011) Chongbo Sun et al.   BIOPHYSICAL JOURNAL

Synthesis and Binding Studies of Novel Diethynyl-Pyridine Amides with Genomic Promoter DNA G-Quadruplexes

(2011) Jyotirmayee Dash et al.   CHEMISTRY-A EUROPEAN JOURNAL

Selective G-quadruplex DNA Stabilizing Agents Based on Bisquinolinium and Bispyridinium Derivatives of 1,8-Naphthyridine

(2011) V. Dhamodharan et al.   JOURNAL OF ORGANIC CHEMISTRY

Highly Efficient Separation of Actinides from Lanthanides by a Phenanthroline-Derived Bis-triazine Ligand

(2011) Frank W. Lewis et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Targeting G-quadruplexes in gene promoters: a novel anticancer strategy?

(2011) Shankar Balasubramanian et al.   NATURE REVIEWS DRUG DISCOVERY

Impact of planarity of unfused aromatic molecules on G-quadruplex binding: Learning from isaindigotone derivatives

(2011) Jin-Qiang Hou et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Promoting the formation and stabilization of human telomeric G-quadruplex DNA, inhibition of telomerase and cytotoxicity by phenanthroline derivatives

(2011) Lihua Wang et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

A click chemistry approach to C3 symmetric, G-quadruplex stabilising ligands

(2010) John E. Moses et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Molecular Dynamics Simulations of DNA-Polycation Complex Formation

(2009) Jesse Ziebarth et al.   BIOPHYSICAL JOURNAL

The Importance of Negative Superhelicity in Inducing the Formation of G-Quadruplex and i-Motif Structures in the c-Myc Promoter: Implications for Drug Targeting and Control of Gene Expression

(2009) Daekyu Sun et al.   JOURNAL OF MEDICINAL CHEMISTRY

Improving physical realism, stereochemistry, and side-chain accuracy in homology modeling: Four approaches that performed well in CASP8

(2009) Elmar Krieger et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

A Metal-Mediated Conformational Switch Controls G-Quadruplex Binding Affinity

(2008) David Monchaud et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Structures, folding patterns, and functions of intramolecular DNA G-quadruplexes found in eukaryotic promoter regions

(2008) Yong Qin et al.   BIOCHIMIE

Rational Design of Novel Benzimidazole-Based Sensor Molecules that Display Positive and Negative Fluorescence Responses to Anions

(2008) Jie Shao et al.   JOURNAL OF FLUORESCENCE

Targeting telomerase and telomeres: a click chemistry approach towards highly selective G-quadruplex ligands

(2008) Adam D. Moorhouse et al.   Molecular BioSystems