Ultrasound activates mechanosensitive TRAAK K+ channels through the lipid membrane

Ultrasound Neuromodulation: A Review of Results, Mechanisms and Safety

(2019) Joseph Blackmore et al.   ULTRASOUND IN MEDICINE AND BIOLOGY

Ultrasound Stimulation Modulates Voltage-Gated Potassium Currents Associated With Action Potential Shape in Hippocampal CA1 Pyramidal Neurons

(2019) Zhengrong Lin et al.   Frontiers in Pharmacology

Mammalian Mechanoelectrical Transduction: Structure and Function of Force-Gated Ion Channels

(2019) Dominique Douguet et al.   CELL

Ultrasonic Neuromodulation via Astrocytic TRPA1

(2019) Soo-Jin Oh et al.   CURRENT BIOLOGY

The mechanosensitive ion channel TRAAK is localized to the mammalian node of Ranvier

(2019) Stephen G Brohawn et al.   eLife

TREK-1 and TRAAK Are Principal K+ Channels at the Nodes of Ranvier for Rapid Action Potential Conduction on Mammalian Myelinated Afferent Nerves

(2019) Hirosato Kanda et al.   NEURON

Ultrasound Elicits Behavioral Responses through Mechanical Effects on Neurons and Ion Channels in a Simple Nervous System

(2018) Jan Kubanek et al.   JOURNAL OF NEUROSCIENCE

Ultrasonic Control of Neural Activity through Activation of the Mechanosensitive Channel MscL

(2018) Jia Ye et al.   NANO LETTERS

Precise multimodal optical control of neural ensemble activity

(2018) Alan R. Mardinly et al.   NATURE NEUROSCIENCE

Ultrasonic Neuromodulation Causes Widespread Cortical Activation via an Indirect Auditory Mechanism

(2018) Tomokazu Sato et al.   NEURON

Ultrasound Produces Extensive Brain Activation via a Cochlear Pathway

(2018) Hongsun Guo et al.   NEURON

Mechanogenetics for the remote and noninvasive control of cancer immunotherapy

(2018) Yijia Pan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Activation of Piezo1 but Not Na V 1.2 Channels by Ultrasound at 43 MHz

(2018) Martin Loynaz Prieto et al.   ULTRASOUND IN MEDICINE AND BIOLOGY

Biomolecular Ultrasound and Sonogenetics

(2018) David Maresca et al.   Annual Review of Chemical and Biomolecular Engineering

The form and function of channelrhodopsin

(2017) Karl Deisseroth et al.   SCIENCE

A Non-canonical Voltage-Sensing Mechanism Controls Gating in K2P K+ Channels

(2016) Marcus Schewe et al.   CELL

Ultrasonic neuromodulation

(2016) Omer Naor et al.   Journal of Neural Engineering

Focused ultrasound neuromodulation of cortical and subcortical brain structures using 1.9 MHz

(2016) Hermes A. S. Kamimura et al.   MEDICAL PHYSICS

Targeted in vivo genetic manipulation of the mouse or rat brain by in utero electroporation with a triple-electrode probe

(2016) Joanna Szczurkowska et al.   Nature Protocols

Kinetic disruption of lipid rafts is a mechanosensor for phospholipase D

(2016) E. Nicholas Petersen et al.   Nature Communications

Ultrasound modulates ion channel currents

(2016) Jan Kubanek et al.   Scientific Reports

Timing of CFTR Pore Opening and Structure of Its Transition State

(2015) Ben Sorum et al.   CELL

Much more than a leak: structure and function of K2P-channels

(2015) Vijay Renigunta et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Sonogenetics is a non-invasive approach to activating neurons in Caenorhabditis elegans

(2015) Stuart Ibsen et al.   Nature Communications

Activation of a Bacterial Mechanosensitive Channel in Mammalian Cells by Cytoskeletal Stress

(2014) Johanna Heureaux et al.   Cellular and Molecular Bioengineering

Physical mechanism for gating and mechanosensitivity of the human TRAAK K+ channel

(2014) Stephen G. Brohawn et al.   NATURE

Electrical brain stimulation for epilepsy

(2014) Robert S. Fisher et al.   Nature Reviews Neurology

The force-from-lipid (FFL) principle of mechanosensitivity, at large and in elements

(2014) Jinfeng Teng et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Mechanosensitivity is mediated directly by the lipid membrane in TRAAK and TREK1 K+channels

(2014) Stephen G. Brohawn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Crystal Structure of the Human K2P TRAAK, a Lipid- and Mechano-Sensitive K+ Ion Channel

(2012) S. G. Brohawn et al.   SCIENCE

Ultrasonic neuromodulation by brain stimulation with transcranial ultrasound

(2011) Yusuf Tufail et al.   Nature Protocols

Deep Brain Stimulation for Parkinson Disease

(2010) Jeff M. Bronstein et al.   ARCHIVES OF NEUROLOGY

Lateral competition for cortical space by layer-specific horizontal circuits

(2010) Hillel Adesnik et al.   NATURE

Transcranial Pulsed Ultrasound Stimulates Intact Brain Circuits

(2010) Yusuf Tufail et al.   NEURON

Molecular Background of Leak K+ Currents: Two-Pore Domain Potassium Channels

(2010) Péter Enyedi et al.   PHYSIOLOGICAL REVIEWS

Remote Excitation of Neuronal Circuits Using Low-Intensity, Low-Frequency Ultrasound

(2008) William J. Tyler et al.   PLoS One