In vivo NIR-II structured-illumination light-sheet microscopy

Advancing nanomedicine with cross‐link functionalized nanoparticles for rapid excretion

(2020) Hongjie Dai et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cortical column and whole-brain imaging with molecular contrast and nanoscale resolution

(2019) Ruixuan Gao et al.   SCIENCE

Prophylactic TLR9 stimulation reduces brain metastasis through microglia activation

(2019) Amit Benbenishty et al.   PLOS BIOLOGY

Molecular Imaging in the Second Near‐Infrared Window

(2019) Hao Wan et al.   ADVANCED FUNCTIONAL MATERIALS

Light-sheet microscopy in the near-infrared II window

(2019) Feifei Wang et al.   NATURE METHODS

Light-Sheet Microscopy in Neuroscience

(2019) Elizabeth M.C. Hillman et al.   Annual Review of Neuroscience

Intravital 2-photon imaging reveals distinct morphology and infiltrative properties of glioblastoma-associated macrophages

(2019) Zhihong Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

In vivo molecular imaging for immunotherapy using ultra-bright near-infrared-IIb rare-earth nanoparticles

(2019) Yeteng Zhong et al.   NATURE BIOTECHNOLOGY

Real-time volumetric microscopy of in vivo dynamics and large-scale samples with SCAPE 2.0

(2019) Venkatakaushik Voleti et al.   NATURE METHODS

Oblique-plane single-molecule localization microscopy for tissues and small intact animals

(2019) Jeongmin Kim et al.   NATURE METHODS

ERK Activation Modulates Cancer Stemness and Motility of a Novel Mouse Oral Squamous Cell Carcinoma Cell Line

(2019) Chen et al.   Cancers

3D NIR-II Molecular Imaging Distinguishes Targeted Organs with High-Performance NIR-II Bioconjugates

(2018) Shoujun Zhu et al.   ADVANCED MATERIALS

Bright quantum dots emitting at ∼1,600 nm in the NIR-IIb window for deep tissue fluorescence imaging

(2018) Mingxi Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Observing the cell in its native state: Imaging subcellular dynamics in multicellular organisms

(2018) Tsung-Li Liu et al.   SCIENCE

Eradication of spontaneous malignancy by local immunotherapy

(2018) Idit Sagiv-Barfi et al.   Science Translational Medicine

3D single-molecule super-resolution microscopy with a tilted light sheet

(2018) Anna-Karin Gustavsson et al.   Nature Communications

A bright organic NIR-II nanofluorophore for three-dimensional imaging into biological tissues

(2018) Hao Wan et al.   Nature Communications

Light-sheet microscopy with attenuation-compensated propagation-invariant beams

(2018) Jonathan Nylk et al.   Science Advances

Near-Infrared IIb Fluorescence Imaging of Vascular Regeneration with Dynamic Tissue Perfusion Measurement and High Spatial Resolution

(2018) Zhuoran Ma et al.   ADVANCED FUNCTIONAL MATERIALS

Three-photon imaging of mouse brain structure and function through the intact skull

(2018) Tianyu Wang et al.   NATURE METHODS

Intravital microscopy of osteolytic progression and therapy response of cancer lesions in the bone

(2018) Eleonora Dondossola et al.   Science Translational Medicine

Imaging Depths of Near-Infrared Quantum Dots in First and Second Optical Windows

(2018) Nayoun Won et al.   Molecular Imaging

Developing a Bright NIR‐II Fluorophore with Fast Renal Excretion and Its Application in Molecular Imaging of Immune Checkpoint PD‐L1

(2018) Hao Wan et al.   ADVANCED FUNCTIONAL MATERIALS

Three-photon light-sheet fluorescence microscopy

(2018) Adrià Escobet-Montalbán et al.   OPTICS LETTERS

In vivo three-photon imaging of activity of GCaMP6-labeled neurons deep in intact mouse brain

(2017) Dimitre G Ouzounov et al.   NATURE METHODS

Three-dimensional live multi-label light-sheet imaging with synchronous excitation-multiplexed structured illumination

(2017) Dongli Xu et al.   OPTICS EXPRESS

Combined OX40L and mTOR blockade controls effector T cell activation while preserving T reg reconstitution after transplant

(2017) Victor Tkachev et al.   Science Translational Medicine

In vivo imaging reveals a tumor-associated macrophage–mediated resistance pathway in anti–PD-1 therapy

(2017) Sean P. Arlauckas et al.   Science Translational Medicine

Boosting the down-shifting luminescence of rare-earth nanocrystals for biological imaging beyond 1500 nm

(2017) Yeteng Zhong et al.   Nature Communications

Next-generation in vivo optical imaging with short-wave infrared quantum dots

(2017) Oliver T. Bruns et al.   Nature Biomedical Engineering

Traumatic Brain Injury Imaging in the Second Near-Infrared Window with a Molecular Fluorophore

(2016) Xiao-Dong Zhang et al.   ADVANCED MATERIALS

Blocking Indolamine-2,3-Dioxygenase Rebound Immune Suppression Boosts Antitumor Effects of Radio-Immunotherapy in Murine Models and Spontaneous Canine Malignancies

(2016) A. M. Monjazeb et al.   CLINICAL CANCER RESEARCH

Rationale for anti-OX40 cancer immunotherapy

(2016) Sandrine Aspeslagh et al.   EUROPEAN JOURNAL OF CANCER

Long-term intravital imaging of the multicolor-coded tumor microenvironment during combination immunotherapy

(2016) Shuhong Qi et al.   eLife

Fluorescence Imaging In Vivo at Wavelengths beyond 1500 nm

(2015) Shuo Diao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

An Effective Immuno-PET Imaging Method to Monitor CD8-Dependent Responses to Immunotherapy

(2015) R. Tavare et al.   CANCER RESEARCH

Biological imaging without autofluorescence in the second near-infrared region

(2015) Shuo Diao et al.   Nano Research

A small-molecule dye for NIR-II imaging

(2015) Alexander L. Antaris et al.   NATURE MATERIALS

Swept confocally-aligned planar excitation (SCAPE) microscopy for high-speed volumetric imaging of behaving organisms

(2015) Matthew B. Bouchard et al.   Nature Photonics

Selective targeting of Toll-like receptors and OX40 inhibit regulatory T-cell function in follicular lymphoma

(2014) Kui Shin Voo et al.   INTERNATIONAL JOURNAL OF CANCER

IL-12 Is Required for Anti-OX40-Mediated CD4 T Cell Survival

(2014) C. E. Ruby et al.   JOURNAL OF IMMUNOLOGY

Through-skull fluorescence imaging of the brain in a new near-infrared window

(2014) Guosong Hong et al.   Nature Photonics

3D live fluorescence imaging of cellular dynamics using Bessel beam plane illumination microscopy

(2014) Liang Gao et al.   Nature Protocols

Advanced CLARITY for rapid and high-resolution imaging of intact tissues

(2014) Raju Tomer et al.   Nature Protocols

Cancer Systems Biology: a peek into the future of patient care?

(2014) Henrica M. J. Werner et al.   Nature Reviews Clinical Oncology

Lattice light-sheet microscopy: Imaging molecules to embryos at high spatiotemporal resolution

(2014) Bi-Chang Chen et al.   SCIENCE

Six-color intravital two-photon imaging of brain tumors and their dynamic microenvironment

(2014) Clément Ricard et al.   Frontiers in Cellular Neuroscience

Ultrafast fluorescence imaging in vivo with conjugated polymer fluorophores in the second near-infrared window

(2014) Guosong Hong et al.   Nature Communications

Cellular imaging of deep organ using two-photon Bessel light-sheet nonlinear structured illumination microscopy

(2014) Ming Zhao et al.   Biomedical Optics Express

OX40 Is a Potent Immune-Stimulating Target in Late-Stage Cancer Patients

(2013) B. D. Curti et al.   CANCER RESEARCH

Depleting tumor-specific Tregs at a single site eradicates disseminated tumors

(2013) Aurélien Marabelle et al.   JOURNAL OF CLINICAL INVESTIGATION

Structural and molecular interrogation of intact biological systems

(2013) Kwanghun Chung et al.   NATURE

In vivo three-photon microscopy of subcortical structures within an intact mouse brain

(2013) Nicholas G. Horton et al.   Nature Photonics

T cell-activation in neuromyelitis optica lesions plays a role in their formation

(2013) Maria Pohl et al.   Acta Neuropathologica Communications

Noninvasive Imaging beyond the Diffraction Limit of 3D Dynamics in Thickly Fluorescent Specimens

(2012) Liang Gao et al.   CELL

In Vivo Optical Imaging of Tumor and Microvascular Response to Ionizing Radiation

(2012) Azusa Maeda et al.   PLoS One

Image formation by linear and nonlinear digital scanned light-sheet fluorescence microscopy with Gaussian and Bessel beam profiles

(2012) Omar E. Olarte et al.   Biomedical Optics Express

Active vaccination with Dickkopf-1 induces protective and therapeutic antitumor immunity in murine multiple myeloma

(2011) J. Qian et al.   BLOOD

Intravital Imaging

(2011) Mikael J. Pittet et al.   CELL

Deep and fast live imaging with two-photon scanned light-sheet microscopy

(2011) Thai V Truong et al.   NATURE METHODS

Rapid three-dimensional isotropic imaging of living cells using Bessel beam plane illumination

(2011) Thomas A Planchon et al.   NATURE METHODS

Blockade of CCL1 Inhibits T Regulatory Cell Suppressive Function Enhancing Tumor Immunity without Affecting T Effector Responses

(2010) D. B. Hoelzinger et al.   JOURNAL OF IMMUNOLOGY

Fast, high-contrast imaging of animal development with scanned light sheet–based structured-illumination microscopy

(2010) Philipp J Keller et al.   NATURE METHODS

Microscopy with self-reconstructing beams

(2010) Florian O. Fahrbach et al.   Nature Photonics

Thinned-skull cranial window technique for long-term imaging of the cortex in live mice

(2010) Guang Yang et al.   Nature Protocols

The immunogenicity of CpG-antigen conjugates

(2009) Hermann Wagner   ADVANCED DRUG DELIVERY REVIEWS

Fast Three-Dimensional Fluorescence Imaging of Activity in Neural Populations by Objective-Coupled Planar Illumination Microscopy

(2008) Terrence F. Holekamp et al.   NEURON

Optically sectioned imaging by oblique plane microscopy

(2008) C. Dunsby   OPTICS EXPRESS