Euler-Lagrange computational fluid dynamics for (bio)reactor scale down: An analysis of organism lifelines

Characterizing bubble column bioreactor performance using computational fluid dynamics

(2016) Dale D. McClure et al.   CHEMICAL ENGINEERING SCIENCE

Plug flow versus stirred tank reactor flow characteristics in two-compartment scale-down bioreactor: Setup-specific influence on the metabolic phenotype and bioprocess performance ofCorynebacterium glutamicum

(2016) Michael H. Limberg et al.   ENGINEERING IN LIFE SCIENCES

Response ofCorynebacterium glutamicumexposed to oscillating cultivation conditions in a two- and a novel three-compartment scale-down bioreactor

(2015) Anja Lemoine et al.   BIOTECHNOLOGY AND BIOENGINEERING

Investigating the interactions between physical and biological heterogeneities in bioreactors using compartment, population balance and metabolic models

(2015) Maxime Pigou et al.   CHEMICAL ENGINEERING SCIENCE

Euler–Lagrange approach to model heterogeneities in stirred tank bioreactors – Comparison to experimental flow characterization and particle tracking

(2015) Angélique Delafosse et al.   CHEMICAL ENGINEERING SCIENCE

The development of an industrial-scale fed-batch fermentation simulation

(2015) Stephen Goldrick et al.   JOURNAL OF BIOTECHNOLOGY

Prelude to rational scale-up of penicillin production: a scale-down study

(2014) Guan Wang et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Integration of microbial kinetics and fluid dynamics toward model-driven scale-up of industrial bioprocesses

(2014) Guan Wang et al.   ENGINEERING IN LIFE SCIENCES

Experimental andin silicoinvestigation of population heterogeneity in continuousSachharomyces cerevisiaescale-down fermentation in a two-compartment setup

(2014) Anna-Lena Heins et al.   JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY

A coupled population balance model and CFD approach for the simulation of mixing issues in lab-scale and industrial bioreactors

(2013) Jérôme Morchain et al.   AICHE JOURNAL

CFD-based compartment model for description of mixing in bioreactors

(2013) Angélique Delafosse et al.   CHEMICAL ENGINEERING SCIENCE

Modeling of aerated stirred tanks with shear-thinning power law liquids

(2012) R. Sungkorn et al.   INTERNATIONAL JOURNAL OF HEAT AND FLUID FLOW

An industrial perspective on bioreactor scale-down: What we can learn from combined large-scale bioprocess and model fluid studies

(2011) Henk Noorman   Biotechnology Journal

Scale-down of penicillin production in Penicillium chrysogenum

(2011) Lodewijk P. de Jonge et al.   Biotechnology Journal

Dynamic gene expression regulation model for growth and penicillin production in Penicillium chrysogenum

(2010) Rutger D. Douma et al.   BIOTECHNOLOGY AND BIOENGINEERING

CFD prediction of fluid flow and mixing in stirred tanks: Numerical issues about the RANS simulations

(2010) M. Coroneo et al.   COMPUTERS & CHEMICAL ENGINEERING

Scale-down simulators for metabolic analysis of large-scale bioprocesses

(2010) Peter Neubauer et al.   CURRENT OPINION IN BIOTECHNOLOGY

Computational Study of Hydrodynamics of a Standard Stirred Tank Reactor and a Large-Scale Multi-Impeller Fermenter

(2009) O. Gunyol et al.   International Journal for Multiscale Computational Engineering