Systematic review and meta-analysis of human transcriptomics reveals neuroinflammation, deficient energy metabolism, and proteostasis failure across neurodegeneration
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Systematic review and meta-analysis of human transcriptomics reveals neuroinflammation, deficient energy metabolism, and proteostasis failure across neurodegeneration
Authors
Keywords
Alzheimer's disease, Amyotrophic lateral sclerosis, Frontotemporal dementia, Lewy body diseases, Meta-analysis, Mitochondrial energy metabolism, Neurodegeneration, Neuroinflammation, Proteostasis, Transcriptomics
Journal
NEUROBIOLOGY OF DISEASE
Volume 149, Issue -, Pages 105225
Publisher
Elsevier BV
Online
2020-12-19
DOI
10.1016/j.nbd.2020.105225
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- An atlas of the protein-coding genes in the human, pig, and mouse brain
- (2020) Evelina Sjöstedt et al. SCIENCE
- Large-scale proteomic analysis of Alzheimer’s disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and astrocyte activation
- (2020) Erik C. B. Johnson et al. NATURE MEDICINE
- Meta-analysis of mouse transcriptomic studies supports a context-dependent astrocyte reaction in acute CNS injury versus neurodegeneration
- (2020) Sudeshna Das et al. Journal of Neuroinflammation
- Meta-Analysis of the Alzheimer’s Disease Human Brain Transcriptome and Functional Dissection in Mouse Models
- (2020) Ying-Wooi Wan et al. Cell Reports
- Astrocytes and microglia play orchestrated roles and respect phagocytic territories during neuronal corpse removal in vivo
- (2020) Eyiyemisi C. Damisah et al. Science Advances
- Tau PTM Profiles Identify Patient Heterogeneity and Stages of Alzheimer’s Disease
- (2020) Hendrik Wesseling et al. CELL
- Gene expression meta-analysis of Parkinson’s disease and its relationship with Alzheimer’s disease
- (2019) Jack Kelly et al. Molecular Brain
- A Meta-Analysis of Alzheimer’s Disease Brain Transcriptomic Data
- (2019) Hamel Patel et al. JOURNAL OF ALZHEIMERS DISEASE
- Single-cell transcriptomic analysis of Alzheimer’s disease
- (2019) Hansruedi Mathys et al. NATURE
- Characterization of the 18 kDa translocator protein (TSPO) expression in post‐mortem normal and Alzheimer's disease brains
- (2019) Yaxing Gui et al. BRAIN PATHOLOGY
- The landscape of multiscale transcriptomic networks and key regulators in Parkinson’s disease
- (2019) Qian Wang et al. Nature Communications
- Integrated MRI and [11 C]-PBR28 PET Imaging in Amyotrophic Lateral sclerosis
- (2018) Mohamad J. Alshikho et al. ANNALS OF NEUROLOGY
- Evidence for a Pan-Neurodegenerative Disease Response in Huntington's and Parkinson's Disease Expression Profiles
- (2018) Adam Labadorf et al. Frontiers in Molecular Neuroscience
- Selective autophagy as a potential therapeutic target for neurodegenerative disorders
- (2018) Aurora Scrivo et al. LANCET NEUROLOGY
- STRING v11: protein–protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets
- (2018) Damian Szklarczyk et al. NUCLEIC ACIDS RESEARCH
- The Gene Ontology Resource: 20 years and still GOing strong
- (2018) NUCLEIC ACIDS RESEARCH
- Diagnosis and management of dementia with Lewy bodies
- (2017) Ian G. McKeith et al. NEUROLOGY
- ATP as a biological hydrotrope
- (2017) Avinash Patel et al. SCIENCE
- Robust hyperparameter estimation protects against hypervariable genes and improves power to detect differential expression
- (2016) Belinda Phipson et al. Annals of Applied Statistics
- Structured States of Disordered Proteins from Genomic Sequences
- (2016) Agnes Toth-Petroczy et al. CELL
- Purification and Characterization of Progenitor and Mature Human Astrocytes Reveals Transcriptional and Functional Differences with Mouse
- (2016) Ye Zhang et al. NEURON
- A transcriptional signature of Alzheimer’s disease is associated with a metastable subproteome at risk for aggregation
- (2016) Prajwal Ciryam et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Influence of microglial activation on neuronal function in Alzheimer's and Parkinson's disease dementia
- (2015) Zhen Fan et al. Alzheimers & Dementia
- limma powers differential expression analyses for RNA-sequencing and microarray studies
- (2015) Matthew E. Ritchie et al. NUCLEIC ACIDS RESEARCH
- The role of protein clearance mechanisms in organismal ageing and age-related diseases
- (2014) David Vilchez et al. Nature Communications
- Integrated multi-cohort transcriptional meta-analysis of neurodegenerative diseases
- (2014) Matthew D Li et al. Acta Neuropathologica Communications
- The Hallmarks of Aging
- (2013) Carlos López-Otín et al. CELL
- The C9orf72 GGGGCC Repeat Is Translated into Aggregating Dipeptide-Repeat Proteins in FTLD/ALS
- (2013) K. Mori et al. SCIENCE
- The sva package for removing batch effects and other unwanted variation in high-throughput experiments
- (2012) Jeffrey T. Leek et al. BIOINFORMATICS
- Detecting disease-associated genes with confounding variable adjustment and the impact on genomic meta-analysis: With application to major depressive disorder
- (2012) Xingbin Wang et al. BMC BIOINFORMATICS
- The diagnosis of dementia due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer's disease
- (2011) Guy M. McKhann et al. Alzheimers & Dementia
- Molecular signatures database (MSigDB) 3.0
- (2011) A. Liberzon et al. BIOINFORMATICS
- Sensitivity of revised diagnostic criteria for the behavioural variant of frontotemporal dementia
- (2011) Katya Rascovsky et al. BRAIN
- Optimally weighted Z-test is a powerful method for combining probabilities in meta-analysis
- (2011) D. V. ZAYKIN JOURNAL OF EVOLUTIONARY BIOLOGY
- A framework for oligonucleotide microarray preprocessing
- (2010) Benilton S. Carvalho et al. BIOINFORMATICS
- Microarray data quality control improves the detection of differentially expressed genes
- (2010) Audrey Kauffmann et al. GENOMICS
- Microglial Cx3cr1 knockout prevents neuron loss in a mouse model of Alzheimer's disease
- (2010) Martin Fuhrmann et al. NATURE NEUROSCIENCE
- PGC-1 , A Potential Therapeutic Target for Early Intervention in Parkinson's Disease
- (2010) B. Zheng et al. Science Translational Medicine
- Mutations in the FUS/TLS Gene on Chromosome 16 Cause Familial Amyotrophic Lateral Sclerosis
- (2009) T. J. Kwiatkowski et al. SCIENCE
- arrayQualityMetrics—a bioconductor package for quality assessment of microarray data
- (2008) Audrey Kauffmann et al. BIOINFORMATICS
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started