Damage-induced chromatome dynamics link Ubiquitin ligase and proteasome recruitment to histone loss and efficient DNA repair

A Cycle of Ubiquitination Regulates Adaptor Function of the Nedd4-Family Ubiquitin Ligase Rsp5

(2020) Chris MacDonald et al.   CURRENT BIOLOGY

The Ubiquitin Ligase TRIP12 Limits PARP1 Trapping and Constrains PARP Inhibitor Efficiency

(2020) Marco Gatti et al.   Cell Reports

DNA Damage-Induced Nucleosome Depletion Enhances Homology Search Independently of Local Break Movement

(2020) Anaïs Cheblal et al.   MOLECULAR CELL

Systematic analysis of linker histone PTM hotspots reveals phosphorylation sites that modulate homologous recombination and DSB repair

(2019) Kuntal Mukherjee et al.   DNA REPAIR

Rpb9-deficient cells are defective in DNA damage response and require histone H3 acetylation for survival

(2018) Henel Sein et al.   Scientific Reports

Chromosome Dynamics in Response to DNA Damage

(2018) Andrew Seeber et al.   Annual Review of Genetics

Increased chromosomal mobility after DNA damage is controlled by interactions between the recombination machinery and the checkpoint

(2018) Michael J. Smith et al.   GENES & DEVELOPMENT

Cell cycle-resolved chromatin proteomics reveals the extent of mitotic preservation of the genomic regulatory landscape

(2018) Paul Adrian Ginno et al.   Nature Communications

Asymmetric Processing of DNA Ends at a Double-Strand Break Leads to Unconstrained Dynamics and Ectopic Translocation

(2018) Isabella Marcomini et al.   Cell Reports

The PRIDE database and related tools and resources in 2019: improving support for quantification data

(2018) Yasset Perez-Riverol et al.   NUCLEIC ACIDS RESEARCH

Bre1-dependent H2B ubiquitination promotes homologous recombination by stimulating histone eviction at DNA breaks

(2018) Sihao Zheng et al.   NUCLEIC ACIDS RESEARCH

Emerging roles of linker histones in regulating chromatin structure and function

(2017) Dmitry V. Fyodorov et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Histone degradation in response to DNA damage enhances chromatin dynamics and recombination rates

(2017) Michael H Hauer et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The INO80 remodeller in transcription, replication and repair

(2017) Jérôme Poli et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Histone degradation in response to DNA damage enhances chromatin dynamics and recombination rates

(2017) Michael H Hauer et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Visualization of Chromatin Decompaction and Break Site Extrusion as Predicted by Statistical Polymer Modeling of Single-Locus Trajectories

(2017) Assaf Amitai et al.   Cell Reports

Asf1 facilitates dephosphorylation of Rad53 after DNA double-strand break repair

(2016) Michael Tsabar et al.   GENES & DEVELOPMENT

Mec1, INO80, and the PAF1 complex cooperate to limit transcription replication conflicts through RNAPII removal during replication stress

(2016) Jérôme Poli et al.   GENES & DEVELOPMENT

Regulation of DNA double-strand break repair by ubiquitin and ubiquitin-like modifiers

(2016) Petra Schwertman et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Recombinational DNA repair is regulated by compartmentalization of DNA lesions at the nuclear pore complex

(2015) Vincent Géli et al.   BIOESSAYS

53BP1 and the LINC Complex Promote Microtubule-Dependent DSB Mobility and DNA Repair

(2015) Francisca Lottersberger et al.   CELL

Chromatin dynamics after DNA damage: The legacy of the access–repair–restore model

(2015) Sophie E. Polo et al.   DNA REPAIR

Rad25 Protein Is Targeted for Degradation by the Ubc4-Ufd4 Pathway

(2015) Xin Bao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

INO80-C and SWR-C: Guardians of the Genome

(2015) Christian-Benedikt Gerhold et al.   JOURNAL OF MOLECULAR BIOLOGY

INO80 Chromatin Remodeler Facilitates Release of RNA Polymerase II from Chromatin for Ubiquitin-Mediated Proteasomal Degradation

(2015) Anne Lafon et al.   MOLECULAR CELL

Histone H1 couples initiation and amplification of ubiquitin signalling after DNA damage

(2015) Tina Thorslund et al.   NATURE

Minimal, encapsulated proteomic-sample processing applied to copy-number estimation in eukaryotic cells

(2014) Nils A Kulak et al.   NATURE METHODS

Nucleosome remodelers in double-strand break repair

(2013) Andrew Seeber et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Checkpoint kinases and the INO80 nucleosome remodeling complex enhance global chromatin mobility in response to DNA damage

(2013) A. Seeber et al.   GENES & DEVELOPMENT

Break-induced replication occurs by conservative DNA synthesis

(2013) R. A. Donnianni et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RNF168 Ubiquitinates K13-15 on H2A/H2AX to Drive DNA Damage Signaling

(2012) Francesca Mattiroli et al.   CELL

Targeted INO80 enhances subnuclear chromatin movement and ectopic homologous recombination

(2012) F. R. Neumann et al.   GENES & DEVELOPMENT

The Ubiquitin-Proteasome System of Saccharomyces cerevisiae

(2012) D. Finley et al.   GENETICS

Chromatin mobility is increased at sites of DNA double-strand breaks

(2012) P. M. Krawczyk et al.   JOURNAL OF CELL SCIENCE

Increased chromosome mobility facilitates homology search during recombination

(2012) Judith Miné-Hattab et al.   NATURE CELL BIOLOGY

Increased mobility of double-strand breaks requires Mec1, Rad9 and the homologous recombination machinery

(2012) Vincent Dion et al.   NATURE CELL BIOLOGY

Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress

(2012) Johnny M. Tkach et al.   NATURE CELL BIOLOGY

Novel E3 Ubiquitin Ligases That Regulate Histone Protein Levels in the Budding Yeast Saccharomyces cerevisiae

(2012) Rakesh Kumar Singh et al.   PLoS One

Global Regulation of H2A.Z Localization by the INO80 Chromatin-Remodeling Enzyme Is Essential for Genome Integrity

(2011) Manolis Papamichos-Chronakis et al.   CELL

Characterization of a Highly Conserved Histone Related Protein, Ydl156w, and Its Functional Associations Using Quantitative Proteomic Analyses

(2011) Joshua M. Gilmore et al.   MOLECULAR & CELLULAR PROTEOMICS

Substantial Histone Reduction Modulates Genomewide Nucleosomal Occupancy and Global Transcriptional Output

(2011) Barbara Celona et al.   PLOS BIOLOGY

Nhp6: A small but powerful effector of chromatin structure in Saccharomyces cerevisiae

(2010) David J. Stillman   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

The SWR1 Histone Replacement Complex Causes Genetic Instability and Genome-Wide Transcription Misregulation in the Absence of H2A.Z

(2010) Macarena Morillo-Huesca et al.   PLoS One

RNF168 Binds and Amplifies Ubiquitin Conjugates on Damaged Chromosomes to Allow Accumulation of Repair Proteins

(2009) Carsten Doil et al.   CELL

Generation and management of excess histones during the cell cycle

(2009) Rakesh Kumar Singh   Frontiers in Bioscience-Landmark

Chromosome-wide Rad51 Spreading and SUMO-H2A.Z-Dependent Chromosome Fixation in Response to a Persistent DNA Double-Strand Break

(2009) Marian Kalocsay et al.   MOLECULAR CELL

Distinct ubiquitin ligases act sequentially for RNA polymerase II polyubiquitylation

(2009) M. Harreman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Histones: Annotating Chromatin

(2008) Eric I. Campos et al.   Annual Review of Genetics

Break dosage, cell cycle stage and DNA replication influence DNA double strand break response

(2008) Christian Zierhut et al.   EMBO JOURNAL

53BP1 promotes non-homologous end joining of telomeres by increasing chromatin mobility

(2008) Nadya Dimitrova et al.   NATURE

Functional Targeting of DNA Damage to a Nuclear Pore-Associated SUMO-Dependent Ubiquitin Ligase

(2008) S. Nagai et al.   SCIENCE

The INO80 chromatin remodeling complex in transcription, replication and repair

(2008) Ronald C. Conaway et al.   TRENDS IN BIOCHEMICAL SCIENCES