Therapeutic effect of the injectable thermosensitive hydrogel loaded with SHP099 on intervertebral disc degeneration

MiRNA-495-3p Attenuates TNF-α Induced Apoptosis and Inflammation in Human Nucleus Pulposus Cells by Targeting IL5RA

(2020) Xi Lin et al.   INFLAMMATION

LINC01121 induced intervertebral disc degeneration via modulating miR‐150‐5p/MMP16 axis

(2020) Xin Chen et al.   JOURNAL OF GENE MEDICINE

Exosomal miR-532–5p from bone marrow mesenchymal stem cells reduce intervertebral disc degeneration by targeting RASSF5

(2020) Guangduo Zhu et al.   EXPERIMENTAL CELL RESEARCH

IVD progenitor cells: a new horizon for understanding disc homeostasis and repair

(2019) Feng-Juan Lyu et al.   Nature Reviews Rheumatology

Intervertebral disc tissue engineering: A brief review

(2019) Janja Stergar et al.   Bosnian Journal of Basic Medical Sciences

Supervised physical therapy vs. home exercise for patients with lumbar spinal stenosis: a randomized controlled trial

(2019) Masakazu Minetama et al.   Spine Journal

Intervertebral Disc Nucleus Repair: Hype or Hope?

(2019) Gauri Tendulkar et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Effect of curcumin on the inflammatory reaction and functional recovery after spinal cord injury in a hyperglycemic rat model

(2019) Young-Seok Lee et al.   Spine Journal

Pathologic Features of the Intervertebral Disc in Young Nova Scotia Duck Tolling Retrievers Confirms Chondrodystrophy Degenerative Phenotype Associated With Genotype

(2019) Brian G. Murphy et al.   VETERINARY PATHOLOGY

Expanded skeletal stem and progenitor cells promote and participate in induced bone regeneration at subcritical BMP-2 dose

(2019) Panagiota Papageorgiou et al.   BIOMATERIALS

Spatiotemporal Expression of 3-B-3(−) and 7-D-4 Chondroitin Sulfation, Tissue Remodeling, and Attempted Repair in an Ovine Model of Intervertebral Disc Degeneration

(2019) Brooke Farrugia et al.   Cartilage

Therapeutic effects of gefitinib-encapsulated thermosensitive injectable hydrogel in intervertebral disc degeneration

(2018) Zongyou Pan et al.   BIOMATERIALS

Strengthening injectable thermo-sensitive NIPAAm- g -chitosan hydrogels using chemical cross-linking of disulfide bonds as scaffolds for tissue engineering

(2018) Shu-Wei Wu et al.   CARBOHYDRATE POLYMERS

Shp2 deletion in hepatocytes suppresses hepatocarcinogenesis driven by oncogenic β-Catenin, PIK3CA and MET

(2018) Jacey J. Liu et al.   JOURNAL OF HEPATOLOGY

Relationships between vitamin D and paraspinal muscle: human data and experimental rat model analysis

(2018) Woo-Seok Bang et al.   Spine Journal

Effect of a bisphosphonate and selective estrogen receptor modulator on bone remodeling in streptozotocin-induced diabetes and ovariectomized rat model

(2018) Young-Seok Lee et al.   Spine Journal

SHP2-Mediated Signal Networks in Stem Cell Homeostasis and Dysfunction

(2018) Chen Kan et al.   Stem Cells International

Reactive oxygen species, aging and articular cartilage homeostasis

(2018) Jesalyn A. Bolduc et al.   FREE RADICAL BIOLOGY AND MEDICINE

RNA binding protein HuR regulates extracellular matrix gene expression and pH homeostasis independent of controlling HIF-1α signaling in nucleus pulposus cells

(2018) Hehai Pan et al.   MATRIX BIOLOGY

Incidental Durotomy in Degenerative Lumbar Spine Surgery – A register study of 64,431 operations

(2018) Fredrik Strömqvist et al.   Spine Journal

Differentiation of pluripotent stem cells into nucleus pulposus progenitor cells for intervertebral disc regeneration

(2018) Kaishun Xia et al.   Current Stem Cell Research & Therapy

Fabrication of P(NIPAAm-co-AAm) coated optical-magnetic quantum dots/silica core-shell nanocomposites for temperature triggered drug release, bioimaging and in vivo tumor inhibition

(2018) Jian Cao et al.   JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE

SHP2 regulates intramembranous ossification by modifying the TGFβ and BMP2 signaling pathway

(2018) Lijun Wang et al.   BONE

Mechanical properties of PNIPAM based hydrogels: A review

(2017) Muhammad Abdul Haq et al.   Materials Science & Engineering C-Materials for Biological Applications

Identification of critical genes in nucleus pulposus cells isolated from degenerated intervertebral discs using bioinformatics analysis

(2017) Zhuangchen Zhu et al.   Molecular Medicine Reports

Cell therapy for the degenerating intervertebral disc

(2017) Wei Tong et al.   Translational Research

Allosteric inhibition of SHP2 phosphatase inhibits cancers driven by receptor tyrosine kinases

(2016) Ying-Nan P. Chen et al.   NATURE

SHP2 sails from physiology to pathology

(2015) Mylène Tajan et al.   European Journal of Medical Genetics

Functions of Shp2 in cancer

(2015) Jie Zhang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Defining the phenotype of young healthy nucleus pulposus cells: Recommendations of the Spine Research Interest Group at the 2014 annual ORS meeting

(2015) Makarand V. Risbud et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Stem cell therapy for intervertebral disc regeneration: obstacles and solutions

(2015) Daisuke Sakai et al.   Nature Reviews Rheumatology

P(NIPAAM-co-HEMA) thermoresponsive hydrogels: an alternative approach for muscle cell sheet engineering

(2014) Chiara Villa et al.   Journal of Tissue Engineering and Regenerative Medicine

Growth differentiation factor 6 and transforming growth factor-beta differentially mediate mesenchymal stem cell differentiation, composition, and micromechanical properties of nucleus pulposus constructs

(2014) Louise E Clarke et al.   ARTHRITIS RESEARCH & THERAPY

Induction of SHP2 Deficiency in Chondrocytes Causes Severe Scoliosis and Kyphosis in Mice

(2013) Harry K. W. Kim et al.   SPINE

The effects of microenvironment in mesenchymal stem cell–based regeneration of intervertebral disc

(2013) Yong-Can Huang et al.   Spine Journal

Genetic polymorphisms associated with intervertebral disc degeneration

(2013) Jillian E. Mayer et al.   Spine Journal

Lumbar disc degeneration and genetic factors are the main risk factors for low back pain in women: the UK Twin Spine Study

(2011) G. Livshits et al.   ANNALS OF THE RHEUMATIC DISEASES

Teriparatide as a Chondroregenerative Therapy for Injury-Induced Osteoarthritis

(2011) E. R. Sampson et al.   Science Translational Medicine

Loss-of-Function Mutations in PTPN11 Cause Metachondromatosis, but Not Ollier Disease or Maffucci Syndrome

(2011) Margot E. Bowen et al.   PLoS Genetics

Differential response of human bone marrow stromal cells to either TGF-β1 or rhGDF-5

(2010) Benjamin Gantenbein-Ritter et al.   EUROPEAN SPINE JOURNAL

Total disc replacement surgery for symptomatic degenerative lumbar disc disease: a systematic review of the literature

(2010) Karin D. van den Eerenbeemt et al.   EUROPEAN SPINE JOURNAL

A Simple Disc Degeneration Model Induced by Percutaneous Needle Puncture in the Rat Tail

(2008) Bin Han et al.   SPINE