Development of α-Selective Glycosylation for the Synthesis of Deoxyfluorinated TN Antigen Analogues

Remote Participation during Glycosylation Reactions of Galactose Building Blocks: Direct Evidence from Cryogenic Vibrational Spectroscopy

(2020) Mateusz Marianski et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Biotinylated Oligo-α-(1 → 4)-d-galactosamines and Their N-Acetylated Derivatives: α-Stereoselective Synthesis and Immunology Application

(2020) Ekaterina D. Kazakova et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Tumor-associated O-glycans of MUC1: Carriers of the glyco-code and targets for cancer vaccine design

(2020) Donella M. Beckwith et al.   SEMINARS IN IMMUNOLOGY

Influence of Functional Groups towards the β-Selective Glycosylation of 2-Azido-2-deoxy Glycosyl Thioglycosides

(2020) Arin Gucchait et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Azidophenylselenylation of glycals towards 2-azido-2-deoxy-selenoglycosides and their application in oligosaccharide synthesis

(2020) Ekaterina D. Kazakova et al.   PURE AND APPLIED CHEMISTRY

Characterization of glycosyl dioxolenium ions and their role in glycosylation reactions

(2020) Thomas Hansen et al.   Nature Communications

Carbohydrate Conjugates in Vaccine Developments

(2020) Shuyao Lang et al.   Frontiers in Chemistry

Mechanisms of Stereodirecting Participation and Ester Migration from Near and Far in Glycosylation and Related Reactions

(2020) Asiri A. Hettikankanamalage et al.   CHEMICAL REVIEWS

Aberrant glycosylation patterns on cancer cells: Therapeutic opportunities for glycodendrimers/metallodendrimers oncology

(2020) Serge Moffett et al.   Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology

A Structurally Simple Vaccine Candidate Reduces Progression and Dissemination of Triple-Negative Breast Cancer

(2020) Amedeo Amedei et al.   iScience

Chemical Strategies to Boost Cancer Vaccines

(2020) Wen-Hao Li et al.   CHEMICAL REVIEWS

The role of fluorine in glycomimetic drug design

(2020) Rachel Hevey   CHEMISTRY-A EUROPEAN JOURNAL

Conformationally Constrained Glycosyl Donors as Tools to Control Glycosylation Outcomes

(2020) Robin A. Jeanneret et al.   JOURNAL OF ORGANIC CHEMISTRY

Structure-Based Design of Potent Tumor-Associated Antigens: Modulation of Peptide Presentation by Single-Atom O/S or O/Se Substitutions at the Glycosidic Linkage

(2019) Ismael Compañón et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The Glycosylation Mechanisms of 6,3-Uronic Acid Lactones

(2019) Hidde Elferink et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Recent advances in carbohydrate-based cancer vaccines

(2019) Ke-Tao Jin et al.   BIOTECHNOLOGY LETTERS

Stereoselectivity in Glycosylation with Deoxofluorinated Glucosazide and Galactosazide Thiodonors

(2019) Martin Kurfiřt et al.   JOURNAL OF ORGANIC CHEMISTRY

Fluorine-modified sialyl-Tn-CRM197 vaccine elicits a robust immune response

(2019) Chengcheng Song et al.   GLYCOCONJUGATE JOURNAL

Mucins and Pathogenic Mucin-Like Molecules Are Immunomodulators During Infection and Targets for Diagnostics and Vaccines

(2019) Sandra Pinzón Martín et al.   Frontiers in Chemistry

The Experimental Evidence in Support of Glycosylation Mechanisms at the SN1–SN2 Interface

(2018) Philip Ouma Adero et al.   CHEMICAL REVIEWS

Synthesis, Liposomal Formulation, and Immunological Evaluation of a Minimalistic Carbohydrate-α-GalCer Vaccine Candidate

(2018) Felix Broecker et al.   JOURNAL OF MEDICINAL CHEMISTRY

Water Sculpts the Distinctive Shapes and Dynamics of the Tn Antigens: Implications for their Molecular Recognition

(2018) Iris Alicia Bermejo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Carbohydrate-based vaccines for oncotherapy

(2018) Meng-Man Wei et al.   MEDICINAL RESEARCH REVIEWS

Synthesis of α-D-GalpN3-(1-3)-D-GalpN3: α- and 3-O-selectivity using 3,4-diol acceptors

(2018) Emil Glibstrup et al.   Beilstein Journal of Organic Chemistry

Synthesis of the Staphylococcus aureus Strain M Capsular Polysaccharide Repeating Unit

(2017) Bas Hagen et al.   ORGANIC LETTERS

A cancer vaccine based on fluorine-modified sialyl-Tn induces robust immune responses in a murine model

(2017) Chengcheng Song et al.   Oncotarget

Cyclopeptide scaffolds in carbohydrate-based synthetic vaccines

(2017) Carlo Pifferi et al.   Biomaterials Science

Recent Advance in Tumor-associated Carbohydrate Antigens (TACAs)-based Antitumor Vaccines

(2016) Danyang Feng et al.   ACS Chemical Biology

Synthesis and in vitro cytotoxicity of acetylated 3-fluoro, 4-fluoro and 3,4-difluoro analogs of D-glucosamine and D-galactosamine

(2016) Štěpán Horník et al.   Beilstein Journal of Organic Chemistry

Short O-GalNAc glycans: regulation and role in tumor development and clinical perspectives

(2016) Joanne Chia et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

The Origin of High Stereoselectivity in Di-tert-butylsilylene-Directed α-Galactosylation

(2016) Akihiro Imamura et al.   JOURNAL OF ORGANIC CHEMISTRY

Phenyl 2-azido-2-deoxy-1-selenogalactosides: a single type of glycosyl donor for the highly stereoselective synthesis of α- and β-2-azido-2-deoxy-d-galactopyranosides

(2016) Elena A. Khatuntseva et al.   TETRAHEDRON LETTERS

Tumor-associated antigens: Tn antigen, sTn antigen, and T antigen

(2016) C. Fu et al.   HLA

Synthesis and biological evaluation of a novel MUC1 glycopeptide conjugate vaccine candidate comprising a 4’-deoxy-4’-fluoro-Thomsen–Friedenreich epitope

(2015) Manuel Johannes et al.   Beilstein Journal of Organic Chemistry

Mucins: A biologically relevant glycan barrier in mucosal protection

(2015) Anthony P. Corfield   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Improvement of the immune efficacy of carbohydrate vaccines by chemical modification on the GM3 antigen

(2015) Xiu-Jing Zheng et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Stereoselective Synthesis of Natural and Non-natural Thomsen-nouveau Antigens and Hydrazide Derivatives

(2015) Ahmad Ali Shaik et al.   ORGANIC LETTERS

Antibody Recognition of Fluorinated Haptens and Antigens

(2014) Maximilian Reindl et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

The effect of electron withdrawing protecting groups at positions 4 and 6 on 1,2-cis galactosylation

(2013) Eva C. Lourenço et al.   TETRAHEDRON

A C-Linked Disaccharide Analogue of Thomsen-Friedenreich Epitope Induces a Strong Immune Response in Mice

(2012) Loay Awad et al.   CHEMISTRY-A EUROPEAN JOURNAL

Effect of Remote Picolinyl and Picoloyl Substituents on the Stereoselectivity of Chemical Glycosylation

(2012) Jagodige P. Yasomanee et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Antibody recognition of fluorinated MUC1 glycopeptide antigens

(2011) Thomas Oberbillig et al.   CHEMICAL COMMUNICATIONS

Sugar-based peptidomimetics inhibit amyloid β-peptide aggregation

(2011) Bertrand Dorgeret et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Study of the Stereoselectivity of 2-Azido-2-deoxygalactosyl Donors: Remote Protecting Group Effects and Temperature Dependency

(2011) Jane Kalikanda et al.   JOURNAL OF ORGANIC CHEMISTRY

Development of highly stereoselective GalN3 donors and their application in the chemical synthesis of precursors of Tn antigen

(2011) George Ngoje et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Enhancement of the Immunogenicity of Synthetic Carbohydrate Vaccines by Chemical Modifications of STn Antigen

(2010) Fan Yang et al.   ACS Chemical Biology

Synthetic Antitumor Vaccines from Tetanus Toxoid Conjugates of MUC1 Glycopeptides with the Thomsen-Friedenreich Antigen and a Fluorine-Substituted Analogue

(2010) Anja Hoffmann-Röder et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Stable GM3Lactone Mimetic Raises Antibodies Specific for the Antigens Expressed on Melanoma Cells

(2010) Annarosa Arcangeli et al.   BIOCONJUGATE CHEMISTRY

Fluorinated Glycosyl Amino Acids for Mucin-Like Glycopeptide Antigen Analogues

(2010) Sarah Wagner et al.   CHEMISTRY-A EUROPEAN JOURNAL

Does Neighboring Group Participation by Non-Vicinal Esters Play a Role in Glycosylation Reactions? Effective Probes for the Detection of Bridging Intermediates

(2008) David Crich et al.   JOURNAL OF ORGANIC CHEMISTRY