Near-Infrared Fluorescent Probe Activated by Nitroreductase for In Vitro and In Vivo Hypoxic Tumor Detection

A near-infrared fluorescent probe for observing thionitrous acid-mediated hydrogen polysulfides formation and fluctuation in cells and in vivo under hypoxia stress

(2020) Xia Zhang et al.   JOURNAL OF HAZARDOUS MATERIALS

Drug Penetration Analysis in 3D Cell Cultures Using Fiducial-Based Semiautomatic Coregistration of MALDI MSI and Immunofluorescence Images

(2019) Markéta Machálková et al.   ANALYTICAL CHEMISTRY

Dimeric BODIPY-loaded liposomes for dual hypoxia marker imaging and activatable photodynamic therapy against tumors

(2018) Huachao Chen et al.   Journal of Materials Chemistry B

Near-infrared off-on fluorescence probe activated by NTR for in vivo hypoxia imaging

(2018) Jinrong Zheng et al.   BIOSENSORS & BIOELECTRONICS

A bioreducible N-oxide-based probe for photoacoustic imaging of hypoxia

(2017) Hailey J. Knox et al.   Nature Communications

Limited Tumor Tissue Drug Penetration Contributes to Primary Resistance against Angiogenesis Inhibitors

(2017) Szilvia Torok et al.   Theranostics

Software update: the ORCA program system, version 4.0

(2017) Frank Neese   Wiley Interdisciplinary Reviews-Computational Molecular Science

Hypoxia-directed and activated theranostic agent: Imaging and treatment of solid tumor

(2016) Rajesh Kumar et al.   BIOMATERIALS

Degradable Controlled-Release Polymers and Polymeric Nanoparticles: Mechanisms of Controlling Drug Release

(2016) Nazila Kamaly et al.   CHEMICAL REVIEWS

Efficient Separation of Europium Over Americium Using Cucurbit-[5]-uril Supramolecule: A Relativistic DFT Based Investigation

(2016) Biswajit Sadhu et al.   INORGANIC CHEMISTRY

Liposomal Texaphyrin Theranostics for Metastatic Liver Cancer

(2016) Min Hee Lee et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Lysosome triggered near-infrared fluorescence imaging of cellular trafficking processes in real time

(2016) Marco Grossi et al.   Nature Communications

Synthesis and evaluation of folate-immobilized198Au@SiO2nanocomposite materials for the diagnosis of folate-receptor-overexpressed tumor

(2016) Jun Young Lee et al.   BULLETIN OF THE KOREAN CHEMICAL SOCIETY

Ultrasensitive Near-Infrared Fluorescence-Enhanced Probe for in Vivo Nitroreductase Imaging

(2015) Yuhao Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Hypoxia-specific ultrasensitive detection of tumours and cancer cells in vivo

(2015) Xianchuang Zheng et al.   Nature Communications

Imaging tumour hypoxia with positron emission tomography

(2014) I N Fleming et al.   BRITISH JOURNAL OF CANCER

“Click and go”: simple and fast folic acid conjugation

(2014) Alexandre F. Trindade et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

High selectivity imaging of nitroreductase using a near-infrared fluorescence probe in hypoxic tumor

(2013) Kehua Xu et al.   CHEMICAL COMMUNICATIONS

Quantum Chemical Challenges for the Binding of Simple Alkanes to Supramolecular Hosts

(2013) Mahesh Sundararajan   JOURNAL OF PHYSICAL CHEMISTRY B

Hypoxia Modulates Infection of Epithelial Cells by Pseudomonas aeruginosa

(2013) Bettina Schaible et al.   PLoS One

Effective peroxidase-like activity of a water-solubilized Fe-aminoclay for use inimmunoassay

(2012) Young-Chul Lee et al.   BIOSENSORS & BIOELECTRONICS

Hypoxia-Inducible Factors in Physiology and Medicine

(2012) Gregg L. Semenza   CELL

Cancer cells that survive radiation therapy acquire HIF-1 activity and translocate towards tumour blood vessels

(2012) Hiroshi Harada et al.   Nature Communications

Hypoxia and hypoxia inducible factors: Diverse roles in liver diseases

(2011) Bharath Nath et al.   HEPATOLOGY

Detailed QM/MM study of the Electron Paramagnetic Resonance Parameters of Nitrosyl Myoglobin

(2011) Mahesh Sundararajan et al.   Journal of Chemical Theory and Computation

BF2-Azadipyrromethenes: Probing the Excited-State Dynamics of a NIR Fluorophore and Photodynamic Therapy Agent

(2011) Pinar Batat et al.   JOURNAL OF PHYSICAL CHEMISTRY A

Cellular Uptake Mediated Off/On Responsive Near-Infrared Fluorescent Nanoparticles

(2011) Aniello Palma et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Folate receptor-α expression in resectable hepatic colorectal cancer metastases: patterns and significance

(2011) Michael D'Angelica et al.   MODERN PATHOLOGY

BF2-Chelated Tetraarylazadipyrromethenes as NIR Fluorochromes

(2010) Mariusz Tasior et al.   BIOCONJUGATE CHEMISTRY

Activatable Molecular Probes for Cancer Imaging

(2010) Seulki Lee et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Tumor Hypoxia Imaging

(2010) Xilin Sun et al.   MOLECULAR IMAGING AND BIOLOGY

Going deeper than microscopy: the optical imaging frontier in biology

(2010) Vasilis Ntziachristos   NATURE METHODS

Folate-targeted therapeutic and imaging agents for cancer

(2009) Philip Stewart Low et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Azide Conjugatable and pH Responsive Near-Infrared Fluorescent Imaging Probes

(2009) Julie Murtagh et al.   ORGANIC LETTERS

Emission under Hypoxia: One-Electron Reduction and Fluorescence Characteristics of an Indolequinone–Coumarin Conjugate

(2008) Kazuhito Tanabe et al.   CHEMBIOCHEM

Folate receptor alpha as a tumor target in epithelial ovarian cancer

(2008) Kimberly R. Kalli et al.   GYNECOLOGIC ONCOLOGY

Immunohistochemical expression of folate receptor α in colorectal carcinoma: patterns and biological significance

(2008) Jinru Shia et al.   HUMAN PATHOLOGY

Discovery and Development of Folic-Acid-Based Receptor Targeting for Imaging and Therapy of Cancer and Inflammatory Diseases

(2007) Philip S. Low et al.   ACCOUNTS OF CHEMICAL RESEARCH